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Ade [cytosol]
Stable Identifier
R-ALL-83951
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
6-aminopurine, adenine
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Sulfur amino acid metabolism (Bos taurus)
Methionine salvage pathway (Bos taurus)
MTA is cleaved and phosphorylated (Bos taurus)
Ade [cytosol]
Metabolism of nucleotides (Bos taurus)
Nucleotide salvage (Bos taurus)
Purine salvage (Bos taurus)
APRT catalyzes the conversion of adenine to AMP (Bos taurus)
Ade [cytosol]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of vitamins, nucleosides, and related molecules (Bos taurus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Bos taurus)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Bos taurus)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Bos taurus)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Bos taurus)
nucleosides [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Bos taurus)
nucleosides [cytosol]
Ade [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Sulfur amino acid metabolism (Caenorhabditis elegans)
Methionine salvage pathway (Caenorhabditis elegans)
MTA is cleaved and phosphorylated (Caenorhabditis elegans)
Ade [cytosol]
Metabolism of nucleotides (Caenorhabditis elegans)
Nucleotide salvage (Caenorhabditis elegans)
Purine salvage (Caenorhabditis elegans)
APRT catalyzes the conversion of adenine to AMP (Caenorhabditis elegans)
Ade [cytosol]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of vitamins, nucleosides, and related molecules (Caenorhabditis elegans)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Caenorhabditis elegans)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Caenorhabditis elegans)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Caenorhabditis elegans)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Caenorhabditis elegans)
nucleosides [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Caenorhabditis elegans)
nucleosides [cytosol]
Ade [cytosol]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Sulfur amino acid metabolism (Canis familiaris)
Methionine salvage pathway (Canis familiaris)
MTA is cleaved and phosphorylated (Canis familiaris)
Ade [cytosol]
Metabolism of nucleotides (Canis familiaris)
Nucleotide salvage (Canis familiaris)
Purine salvage (Canis familiaris)
APRT catalyzes the conversion of adenine to AMP (Canis familiaris)
Ade [cytosol]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of vitamins, nucleosides, and related molecules (Canis familiaris)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Canis familiaris)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Canis familiaris)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Canis familiaris)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Canis familiaris)
nucleosides [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Canis familiaris)
nucleosides [cytosol]
Ade [cytosol]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Sulfur amino acid metabolism (Danio rerio)
Methionine salvage pathway (Danio rerio)
MTA is cleaved and phosphorylated (Danio rerio)
Ade [cytosol]
Metabolism of nucleotides (Danio rerio)
Nucleotide salvage (Danio rerio)
Purine salvage (Danio rerio)
APRT catalyzes the conversion of adenine to AMP (Danio rerio)
Ade [cytosol]
Transport of small molecules (Dictyostelium discoideum)
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Transport of vitamins, nucleosides, and related molecules (Dictyostelium discoideum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Dictyostelium discoideum)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Dictyostelium discoideum)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Dictyostelium discoideum)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Dictyostelium discoideum)
nucleosides [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Dictyostelium discoideum)
nucleosides [cytosol]
Ade [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Sulfur amino acid metabolism (Drosophila melanogaster)
Methionine salvage pathway (Drosophila melanogaster)
MTA is cleaved and phosphorylated (Drosophila melanogaster)
Ade [cytosol]
Metabolism of nucleotides (Drosophila melanogaster)
Nucleotide salvage (Drosophila melanogaster)
Purine salvage (Drosophila melanogaster)
APRT catalyzes the conversion of adenine to AMP (Drosophila melanogaster)
Ade [cytosol]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of vitamins, nucleosides, and related molecules (Drosophila melanogaster)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Drosophila melanogaster)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Drosophila melanogaster)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Drosophila melanogaster)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Drosophila melanogaster)
nucleosides [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Drosophila melanogaster)
nucleosides [cytosol]
Ade [cytosol]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Sulfur amino acid metabolism (Gallus gallus)
Methionine salvage pathway (Gallus gallus)
MTA is cleaved and phosphorylated (Gallus gallus)
Ade [cytosol]
Metabolism of nucleotides (Gallus gallus)
Nucleotide salvage (Gallus gallus)
Purine salvage (Gallus gallus)
APRT catalyzes the conversion of adenine to AMP (Gallus gallus)
Ade [cytosol]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of vitamins, nucleosides, and related molecules (Gallus gallus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Gallus gallus)
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Gallus gallus)
nucleosides [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Gallus gallus)
nucleosides [cytosol]
Ade [cytosol]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of nucleotide metabolism (Homo sapiens)
Nucleotide salvage defects (Homo sapiens)
Defective APRT disrupts adenine salvage (Homo sapiens)
Defective APRT does not convert adenine to AMP (Homo sapiens)
Ade [cytosol]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Sulfur amino acid metabolism (Homo sapiens)
Methionine salvage pathway (Homo sapiens)
MTA is cleaved and phosphorylated (Homo sapiens)
Ade [cytosol]
Metabolism of nucleotides (Homo sapiens)
Nucleotide salvage (Homo sapiens)
Purine salvage (Homo sapiens)
APRT catalyzes the conversion of adenine to AMP (Homo sapiens)
Ade [cytosol]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Homo sapiens)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Homo sapiens)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Homo sapiens)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Homo sapiens)
nucleosides [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Homo sapiens)
nucleosides [cytosol]
Ade [cytosol]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Sulfur amino acid metabolism (Mus musculus)
Methionine salvage pathway (Mus musculus)
MTA is cleaved and phosphorylated (Mus musculus)
Ade [cytosol]
Metabolism of nucleotides (Mus musculus)
Nucleotide salvage (Mus musculus)
Purine salvage (Mus musculus)
APRT catalyzes the conversion of adenine to AMP (Mus musculus)
Ade [cytosol]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of vitamins, nucleosides, and related molecules (Mus musculus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Mus musculus)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Mus musculus)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Mus musculus)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Mus musculus)
nucleosides [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Mus musculus)
nucleosides [cytosol]
Ade [cytosol]
Transport of small molecules (Plasmodium falciparum)
SLC-mediated transmembrane transport (Plasmodium falciparum)
Transport of vitamins, nucleosides, and related molecules (Plasmodium falciparum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Plasmodium falciparum)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Plasmodium falciparum)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Plasmodium falciparum)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Plasmodium falciparum)
nucleosides [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Plasmodium falciparum)
nucleosides [cytosol]
Ade [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Sulfur amino acid metabolism (Rattus norvegicus)
Methionine salvage pathway (Rattus norvegicus)
MTA is cleaved and phosphorylated (Rattus norvegicus)
Ade [cytosol]
Metabolism of nucleotides (Rattus norvegicus)
Nucleotide salvage (Rattus norvegicus)
Purine salvage (Rattus norvegicus)
APRT catalyzes the conversion of adenine to AMP (Rattus norvegicus)
Ade [cytosol]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of vitamins, nucleosides, and related molecules (Rattus norvegicus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Rattus norvegicus)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Rattus norvegicus)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Rattus norvegicus)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Rattus norvegicus)
nucleosides [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Rattus norvegicus)
nucleosides [cytosol]
Ade [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Sulfur amino acid metabolism (Saccharomyces cerevisiae)
Methionine salvage pathway (Saccharomyces cerevisiae)
MTA is cleaved and phosphorylated (Saccharomyces cerevisiae)
Ade [cytosol]
Metabolism of nucleotides (Saccharomyces cerevisiae)
Nucleotide salvage (Saccharomyces cerevisiae)
Purine salvage (Saccharomyces cerevisiae)
APRT catalyzes the conversion of adenine to AMP (Saccharomyces cerevisiae)
Ade [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Sulfur amino acid metabolism (Schizosaccharomyces pombe)
Methionine salvage pathway (Schizosaccharomyces pombe)
MTA is cleaved and phosphorylated (Schizosaccharomyces pombe)
Ade [cytosol]
Metabolism of nucleotides (Schizosaccharomyces pombe)
Nucleotide salvage (Schizosaccharomyces pombe)
Purine salvage (Schizosaccharomyces pombe)
APRT catalyzes the conversion of adenine to AMP (Schizosaccharomyces pombe)
Ade [cytosol]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Sulfur amino acid metabolism (Sus scrofa)
Methionine salvage pathway (Sus scrofa)
MTA is cleaved and phosphorylated (Sus scrofa)
Ade [cytosol]
Metabolism of nucleotides (Sus scrofa)
Nucleotide salvage (Sus scrofa)
Purine salvage (Sus scrofa)
APRT catalyzes the conversion of adenine to AMP (Sus scrofa)
Ade [cytosol]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of vitamins, nucleosides, and related molecules (Sus scrofa)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Sus scrofa)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Sus scrofa)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Sus scrofa)
ligands of SLC29A2 [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Sus scrofa)
nucleosides [cytosol]
Ade [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Sus scrofa)
nucleosides [cytosol]
Ade [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Sulfur amino acid metabolism (Xenopus tropicalis)
Methionine salvage pathway (Xenopus tropicalis)
MTA is cleaved and phosphorylated (Xenopus tropicalis)
Ade [cytosol]
Metabolism of nucleotides (Xenopus tropicalis)
Nucleotide salvage (Xenopus tropicalis)
Purine salvage (Xenopus tropicalis)
APRT catalyzes the conversion of adenine to AMP (Xenopus tropicalis)
Ade [cytosol]
External Reference Information
External Reference
adenine [ChEBI:16708]
Participates
as an input of
Defective APRT does not convert adenine to AMP (Homo sapiens)
APRT catalyzes the conversion of adenine to AMP (Saccharomyces cerevisiae)
APRT catalyzes the conversion of adenine to AMP (Schizosaccharomyces pombe)
APRT catalyzes the conversion of adenine to AMP (Caenorhabditis elegans)
APRT catalyzes the conversion of adenine to AMP (Drosophila melanogaster)
APRT catalyzes the conversion of adenine to AMP (Gallus gallus)
APRT catalyzes the conversion of adenine to AMP (Xenopus tropicalis)
APRT catalyzes the conversion of adenine to AMP (Danio rerio)
APRT catalyzes the conversion of adenine to AMP (Sus scrofa)
APRT catalyzes the conversion of adenine to AMP (Bos taurus)
APRT catalyzes the conversion of adenine to AMP (Canis familiaris)
APRT catalyzes the conversion of adenine to AMP (Rattus norvegicus)
APRT catalyzes the conversion of adenine to AMP (Mus musculus)
APRT catalyzes the conversion of adenine to AMP (Homo sapiens)
as a member of
ligands of SLC29A2 [cytosol]
nucleosides [cytosol]
as an output of
MTA is cleaved and phosphorylated (Saccharomyces cerevisiae)
MTA is cleaved and phosphorylated (Schizosaccharomyces pombe)
MTA is cleaved and phosphorylated (Caenorhabditis elegans)
MTA is cleaved and phosphorylated (Drosophila melanogaster)
MTA is cleaved and phosphorylated (Gallus gallus)
MTA is cleaved and phosphorylated (Xenopus tropicalis)
MTA is cleaved and phosphorylated (Danio rerio)
MTA is cleaved and phosphorylated (Sus scrofa)
MTA is cleaved and phosphorylated (Canis familiaris)
MTA is cleaved and phosphorylated (Rattus norvegicus)
MTA is cleaved and phosphorylated (Mus musculus)
MTA is cleaved and phosphorylated (Homo sapiens)
MTA is cleaved and phosphorylated (Bos taurus)
Other forms of this molecule
Ade [nucleoplasm]
Ade [extracellular region]
Ade [lysosomal lumen]
Cross References
Guide to Pharmacology - Ligands
4788
COMPOUND
C00147
PubChem Substance
8144939
HMDB Metabolite
HMDB0000034
ZINC
ZINC000000000882
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![Ade [cytosol] icon](/icon/R-ICO-014543.svg){kind=icon}
