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9cRA [cytosol]
Stable Identifier
R-ALL-5362520
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
9-cis-retinoic acid
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Cytochrome P450 - arranged by substrate type (Bos taurus)
Vitamins (Bos taurus)
CYP26C1 4-hydroxylates 9cRA (Bos taurus)
9cRA [cytosol]
Signal Transduction (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
Signaling by Retinoic Acid (Bos taurus)
RA biosynthesis pathway (Bos taurus)
ALDH8A1 oxidises 9cRAL to 9cRA (Bos taurus)
9cRA [cytosol]
CYP26C1 4-hydroxylates 9cRA (Bos taurus)
9cRA [cytosol]
Signal Transduction (Caenorhabditis elegans)
Signaling by Nuclear Receptors (Caenorhabditis elegans)
Signaling by Retinoic Acid (Caenorhabditis elegans)
RA biosynthesis pathway (Caenorhabditis elegans)
ALDH8A1 oxidises 9cRAL to 9cRA (Caenorhabditis elegans)
9cRA [cytosol]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Cytochrome P450 - arranged by substrate type (Canis familiaris)
Vitamins (Canis familiaris)
CYP26C1 4-hydroxylates 9cRA (Canis familiaris)
9cRA [cytosol]
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
Signaling by Retinoic Acid (Canis familiaris)
RA biosynthesis pathway (Canis familiaris)
ALDH8A1 oxidises 9cRAL to 9cRA (Canis familiaris)
9cRA [cytosol]
CYP26C1 4-hydroxylates 9cRA (Canis familiaris)
9cRA [cytosol]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
Cytochrome P450 - arranged by substrate type (Danio rerio)
Vitamins (Danio rerio)
CYP26C1 4-hydroxylates 9cRA (Danio rerio)
9cRA [cytosol]
Signal Transduction (Danio rerio)
Signaling by Nuclear Receptors (Danio rerio)
Signaling by Retinoic Acid (Danio rerio)
RA biosynthesis pathway (Danio rerio)
ALDH8A1 oxidises 9cRAL to 9cRA (Danio rerio)
9cRA [cytosol]
CYP26C1 4-hydroxylates 9cRA (Danio rerio)
9cRA [cytosol]
Signal Transduction (Dictyostelium discoideum)
Signaling by Nuclear Receptors (Dictyostelium discoideum)
Signaling by Retinoic Acid (Dictyostelium discoideum)
RA biosynthesis pathway (Dictyostelium discoideum)
ALDH8A1 oxidises 9cRAL to 9cRA (Dictyostelium discoideum)
9cRA [cytosol]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
Cytochrome P450 - arranged by substrate type (Gallus gallus)
Vitamins (Gallus gallus)
CYP26C1 4-hydroxylates 9cRA (Gallus gallus)
9cRA [cytosol]
Signal Transduction (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
Signaling by Retinoic Acid (Gallus gallus)
RA biosynthesis pathway (Gallus gallus)
ALDH8A1 oxidises 9cRAL to 9cRA (Gallus gallus)
9cRA [cytosol]
CYP26C1 4-hydroxylates 9cRA (Gallus gallus)
9cRA [cytosol]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Metabolic disorders of biological oxidation enzymes (Homo sapiens)
Defective CYP26C1 causes FFDD4 (Homo sapiens)
Defective CYP26C1 does not 4-hydroxylate 9cRA (Homo sapiens)
9cRA [cytosol]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Vitamins (Homo sapiens)
CYP26C1 4-hydroxylates 9cRA (Homo sapiens)
9cRA [cytosol]
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
Signaling by Retinoic Acid (Homo sapiens)
RA biosynthesis pathway (Homo sapiens)
ALDH8A1 oxidises 9cRAL to 9cRA (Homo sapiens)
9cRA [cytosol]
CYP26C1 4-hydroxylates 9cRA (Homo sapiens)
9cRA [cytosol]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Vitamins (Mus musculus)
CYP26C1 4-hydroxylates 9cRA (Mus musculus)
9cRA [cytosol]
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
Signaling by Retinoic Acid (Mus musculus)
RA biosynthesis pathway (Mus musculus)
ALDH8A1 oxidises 9cRAL to 9cRA (Mus musculus)
9cRA [cytosol]
CYP26C1 4-hydroxylates 9cRA (Mus musculus)
9cRA [cytosol]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Cytochrome P450 - arranged by substrate type (Rattus norvegicus)
Vitamins (Rattus norvegicus)
CYP26C1 4-hydroxylates 9cRA (Rattus norvegicus)
9cRA [cytosol]
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
Signaling by Retinoic Acid (Rattus norvegicus)
RA biosynthesis pathway (Rattus norvegicus)
ALDH8A1 oxidises 9cRAL to 9cRA (Rattus norvegicus)
9cRA [cytosol]
CYP26C1 4-hydroxylates 9cRA (Rattus norvegicus)
9cRA [cytosol]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Cytochrome P450 - arranged by substrate type (Sus scrofa)
Vitamins (Sus scrofa)
CYP26C1 4-hydroxylates 9cRA (Sus scrofa)
9cRA [cytosol]
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
Signaling by Retinoic Acid (Sus scrofa)
RA biosynthesis pathway (Sus scrofa)
ALDH8A1 oxidises 9cRAL to 9cRA (Sus scrofa)
9cRA [cytosol]
CYP26C1 4-hydroxylates 9cRA (Sus scrofa)
9cRA [cytosol]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase I - Functionalization of compounds (Xenopus tropicalis)
Cytochrome P450 - arranged by substrate type (Xenopus tropicalis)
Vitamins (Xenopus tropicalis)
CYP26C1 4-hydroxylates 9cRA (Xenopus tropicalis)
9cRA [cytosol]
Signal Transduction (Xenopus tropicalis)
Signaling by Nuclear Receptors (Xenopus tropicalis)
Signaling by Retinoic Acid (Xenopus tropicalis)
RA biosynthesis pathway (Xenopus tropicalis)
ALDH8A1 oxidises 9cRAL to 9cRA (Xenopus tropicalis)
9cRA [cytosol]
CYP26C1 4-hydroxylates 9cRA (Xenopus tropicalis)
9cRA [cytosol]
External Reference Information
External Reference
9-cis-retinoic acid [ChEBI:50648]
Participates
as an input of
Defective CYP26C1 does not 4-hydroxylate 9cRA (Homo sapiens)
CYP26C1 4-hydroxylates 9cRA (Gallus gallus)
CYP26C1 4-hydroxylates 9cRA (Xenopus tropicalis)
CYP26C1 4-hydroxylates 9cRA (Danio rerio)
CYP26C1 4-hydroxylates 9cRA (Sus scrofa)
CYP26C1 4-hydroxylates 9cRA (Bos taurus)
CYP26C1 4-hydroxylates 9cRA (Canis familiaris)
CYP26C1 4-hydroxylates 9cRA (Rattus norvegicus)
CYP26C1 4-hydroxylates 9cRA (Mus musculus)
CYP26C1 4-hydroxylates 9cRA (Homo sapiens)
as an output of
ALDH8A1 oxidises 9cRAL to 9cRA (Dictyostelium discoideum)
ALDH8A1 oxidises 9cRAL to 9cRA (Caenorhabditis elegans)
ALDH8A1 oxidises 9cRAL to 9cRA (Gallus gallus)
ALDH8A1 oxidises 9cRAL to 9cRA (Xenopus tropicalis)
ALDH8A1 oxidises 9cRAL to 9cRA (Danio rerio)
ALDH8A1 oxidises 9cRAL to 9cRA (Sus scrofa)
ALDH8A1 oxidises 9cRAL to 9cRA (Bos taurus)
ALDH8A1 oxidises 9cRAL to 9cRA (Canis familiaris)
ALDH8A1 oxidises 9cRAL to 9cRA (Rattus norvegicus)
ALDH8A1 oxidises 9cRAL to 9cRA (Mus musculus)
ALDH8A1 oxidises 9cRAL to 9cRA (Homo sapiens)
Other forms of this molecule
9cRA [extracellular region]
9cRA [nucleoplasm]
Cross References
Guide to Pharmacology - Ligands
2645
COMPOUND
C15493
HMDB Metabolite
HMDB0002369
ZINC
000012661824
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