Reactome | Mn2+ [lysosomal lumen]

Mn2+ [lysosomal lumen]

Stable Identifier

R-ALL-5357557

Type

Chemical Compound [SimpleEntity]

Compartment

lysosomal lumen

Synonyms

Manganese, manganese(2+), Mn(II)

Locations in the PathwayBrowser

for Species:

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Metabolism (Bos taurus)

- Metabolism of carbohydrates (Bos taurus)
  - Glycogen metabolism (Bos taurus)
    - Glycogen breakdown (glycogenolysis) (Bos taurus)
      - GAA hydrolyzes lysosomal glycogen (Bos taurus)
        
        glycogen-GYG1 dimer [lysosomal lumen] (Bos taurus)
        
        Mn2+ [lysosomal lumen]
        
        poly((1,4)-alpha-glucosyl)GYG1 dimer [lysosomal lumen] (Bos taurus)
        
        Mn2+ [lysosomal lumen]

Metabolism (Canis familiaris)

- Metabolism of carbohydrates (Canis familiaris)
  - Glycogen metabolism (Canis familiaris)
    - Glycogen breakdown (glycogenolysis) (Canis familiaris)
      - GAA hydrolyzes lysosomal glycogen (Canis familiaris)
        
        glycogen-GYG1 dimer [lysosomal lumen] (Canis familiaris)
        
        Mn2+ [lysosomal lumen]
        
        poly((1,4)-alpha-glucosyl)GYG1 dimer [lysosomal lumen] (Canis familiaris)
        
        Mn2+ [lysosomal lumen]

Metabolism (Dictyostelium discoideum)

- Metabolism of carbohydrates (Dictyostelium discoideum)
  - Glycogen metabolism (Dictyostelium discoideum)
    - Glycogen breakdown (glycogenolysis) (Dictyostelium discoideum)
      - GAA hydrolyzes lysosomal glycogen (Dictyostelium discoideum)
        
        glycogen-GYG1 dimer [lysosomal lumen] (Dictyostelium discoideum)
        
        Mn2+ [lysosomal lumen]
        
        poly((1,4)-alpha-glucosyl)GYG1 dimer [lysosomal lumen] (Dictyostelium discoideum)
        
        Mn2+ [lysosomal lumen]

Disease (Homo sapiens)

- Diseases of metabolism (Homo sapiens)
  - Diseases of carbohydrate metabolism (Homo sapiens)
    - Glycogen storage diseases (Homo sapiens)
      - Glycogen storage disease type II (GAA) (Homo sapiens)
        
        Defective GAA does not hydrolyze lysosomal glycogen (Homo sapiens)
        
        glycogen-GYG1 dimer [lysosomal lumen] (Homo sapiens)
        
        Mn2+ [lysosomal lumen]

Metabolism (Homo sapiens)

- Metabolism of carbohydrates (Homo sapiens)
  - Glycogen metabolism (Homo sapiens)
    - Glycogen breakdown (glycogenolysis) (Homo sapiens)
      - GAA hydrolyzes lysosomal glycogen (Homo sapiens)
        
        glycogen-GYG1 dimer [lysosomal lumen] (Homo sapiens)
        
        Mn2+ [lysosomal lumen]
        
        poly((1,4)-alpha-glucosyl)GYG1 dimer [lysosomal lumen] (Homo sapiens)
        
        Mn2+ [lysosomal lumen]

Metabolism (Mus musculus)

- Metabolism of carbohydrates (Mus musculus)
  - Glycogen metabolism (Mus musculus)
    - Glycogen breakdown (glycogenolysis) (Mus musculus)
      - GAA hydrolyzes lysosomal glycogen (Mus musculus)
        
        glycogen-GYG1 dimer [lysosomal lumen] (Mus musculus)
        
        Mn2+ [lysosomal lumen]
        
        poly((1,4)-alpha-glucosyl)GYG1 dimer [lysosomal lumen] (Mus musculus)
        
        Mn2+ [lysosomal lumen]

Metabolism (Rattus norvegicus)

- Metabolism of carbohydrates (Rattus norvegicus)
  - Glycogen metabolism (Rattus norvegicus)
    - Glycogen breakdown (glycogenolysis) (Rattus norvegicus)
      - GAA hydrolyzes lysosomal glycogen (Rattus norvegicus)
        
        glycogen-GYG1 dimer [lysosomal lumen] (Rattus norvegicus)
        
        Mn2+ [lysosomal lumen]
        
        poly((1,4)-alpha-glucosyl)GYG1 dimer [lysosomal lumen] (Rattus norvegicus)
        
        Mn2+ [lysosomal lumen]

Metabolism (Schizosaccharomyces pombe)

- Metabolism of carbohydrates (Schizosaccharomyces pombe)
  - Glycogen metabolism (Schizosaccharomyces pombe)
    - Glycogen breakdown (glycogenolysis) (Schizosaccharomyces pombe)
      - GAA hydrolyzes lysosomal glycogen (Schizosaccharomyces pombe)
        
        glycogen-GYG1 dimer [lysosomal lumen] (Schizosaccharomyces pombe)
        
        Mn2+ [lysosomal lumen]
        
        poly((1,4)-alpha-glucosyl)GYG1 dimer [lysosomal lumen] (Schizosaccharomyces pombe)
        
        Mn2+ [lysosomal lumen]

Metabolism (Sus scrofa)

- Metabolism of carbohydrates (Sus scrofa)
  - Glycogen metabolism (Sus scrofa)
    - Glycogen breakdown (glycogenolysis) (Sus scrofa)
      - GAA hydrolyzes lysosomal glycogen (Sus scrofa)
        
        glycogen-GYG1 dimer [lysosomal lumen] (Sus scrofa)
        
        Mn2+ [lysosomal lumen]
        
        poly((1,4)-alpha-glucosyl)GYG1 dimer [lysosomal lumen] (Sus scrofa)
        
        Mn2+ [lysosomal lumen]

External Reference Information

External Reference

manganese(2+) [ChEBI:29035]

Participates

as a component of

Other forms of this molecule

Mn2+ [nucleoplasm]

Mn2+ [endoplasmic reticulum lumen]

Mn2+ [Golgi lumen]

Mn2+ [phagocytic vesicle lumen]

Mn2+ [mitochondrial matrix]

Mn2+ [Golgi membrane]

Mn2+ [endoplasmic reticulum membrane]

Mn2+ [cytosol]

Mn2+ [extracellular region]

Cross References

AraCyc

MN+2

CAS

16397-91-4, 7439-96-5

ChEBI

29035

COMPOUND

C00034

PubChem Compound

27854

HMDB Metabolite

HMDB0001333

KEGG Gene

C19610