mRNA Transcript Targeted by KSRP [cytosol]

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KSRP binds AU-rich elements in the following mRNAs: IL-8, LDLR, and NOS2 (iNOS). Binding of KSRP to the mRNA encoding Beta-catenin is inferred from mouse.

Literature References
PubMed ID Title Journal Year
15514971 IL-1beta induces stabilization of IL-8 mRNA in malignant breast cancer cells via the 3' untranslated region: Involvement of divergent RNA-binding factors HuR, KSRP and TIAR

Suswam, EA, Nabors, LB, Huang, Y, Yang, X, King, PH

Int J Cancer 2005
19141871 Identification of mRNA binding proteins that regulate the stability of LDL receptor mRNA through AU-rich elements

Li, H, Chen, W, Zhou, Y, Abidi, P, Sharpe, O, Robinson, WH, Kraemer, FB, Liu, J

J Lipid Res 2009
19854161 Transcriptional and post-transcriptional regulation of iNOS expression in human chondrocytes

Schmidt, N, Pautz, A, Art, J, Rauschkolb, P, Jung, M, Erkel, G, Goldring, MB, Kleinert, H

Biochem Pharmacol 2010
17177604 The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling

Gherzi, R, Trabucchi, M, Ponassi, M, Ruggiero, T, Corte, G, Moroni, C, Chen, CY, Khabar, KS, Andersen, JS, Briata, P

PLoS Biol 2006
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