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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Editorial Calendar
Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
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DDCX [extracellular region]
Stable Identifier
R-ALL-449678
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
lauric acid, dodecanoic acid, Dodecylcarboxylate, Dodecanoate
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
Free fatty acids regulate insulin secretion (Bos taurus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Bos taurus)
FFAR1 binds fatty acids (Bos taurus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands activate Gq (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Metabolism of proteins (Bos taurus)
Peptide hormone metabolism (Bos taurus)
Incretin synthesis, secretion, and inactivation (Bos taurus)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (Bos taurus)
Glucagon-like Peptide 1 is secreted from intestinal L cells (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (Bos taurus)
Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Sensory Perception (Bos taurus)
Olfactory Signaling Pathway (Bos taurus)
odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Bos taurus)
odorant [extracellular region]
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (q) signalling events (Bos taurus)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Bos taurus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Bos taurus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Bos taurus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
GPCR ligand binding (Bos taurus)
Class A/1 (Rhodopsin-like receptors) (Bos taurus)
Free fatty acid receptors (Bos taurus)
Receptor FFAR1 binds free fatty acids (Bos taurus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of vitamins, nucleosides, and related molecules (Bos taurus)
Transport of fatty acids (Bos taurus)
SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Bos taurus)
LCFAs [extracellular region]
DDCX [extracellular region]
Signal Transduction (Caenorhabditis elegans)
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (q) signalling events (Caenorhabditis elegans)
The Ligand:GPCR:Gq complex dissociates (Caenorhabditis elegans)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Caenorhabditis elegans)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of vitamins, nucleosides, and related molecules (Caenorhabditis elegans)
Transport of fatty acids (Caenorhabditis elegans)
SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Caenorhabditis elegans)
LCFAs [extracellular region]
DDCX [extracellular region]
Metabolism (Canis familiaris)
Integration of energy metabolism (Canis familiaris)
Regulation of insulin secretion (Canis familiaris)
Free fatty acids regulate insulin secretion (Canis familiaris)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Canis familiaris)
FFAR1 binds fatty acids (Canis familiaris)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands activate Gq (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Metabolism of proteins (Canis familiaris)
Peptide hormone metabolism (Canis familiaris)
Incretin synthesis, secretion, and inactivation (Canis familiaris)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (Canis familiaris)
Glucagon-like Peptide 1 is secreted from intestinal L cells (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (Canis familiaris)
Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Sensory Perception (Canis familiaris)
Olfactory Signaling Pathway (Canis familiaris)
odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Canis familiaris)
odorant [extracellular region]
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 [plasma membrane] (Canis familiaris)
odorant:Olfactory receptor [plasma membrane] (Canis familiaris)
OR51B5:ligand [plasma membrane] (Canis familiaris)
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
Signal Transduction (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (q) signalling events (Canis familiaris)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Canis familiaris)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
GPCR ligand binding (Canis familiaris)
Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
Free fatty acid receptors (Canis familiaris)
Receptor FFAR1 binds free fatty acids (Canis familiaris)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of vitamins, nucleosides, and related molecules (Canis familiaris)
Transport of fatty acids (Canis familiaris)
SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Canis familiaris)
LCFAs [extracellular region]
DDCX [extracellular region]
Sensory Perception (Danio rerio)
Olfactory Signaling Pathway (Danio rerio)
odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Danio rerio)
odorant [extracellular region]
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 [plasma membrane] (Danio rerio)
odorant:Olfactory receptor [plasma membrane] (Danio rerio)
OR51B5:ligand [plasma membrane] (Danio rerio)
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of vitamins, nucleosides, and related molecules (Danio rerio)
Transport of fatty acids (Danio rerio)
SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Danio rerio)
LCFAs [extracellular region]
DDCX [extracellular region]
Signal Transduction (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (q) signalling events (Drosophila melanogaster)
The Ligand:GPCR:Gq complex dissociates (Drosophila melanogaster)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Drosophila melanogaster)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of vitamins, nucleosides, and related molecules (Drosophila melanogaster)
Transport of fatty acids (Drosophila melanogaster)
SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Drosophila melanogaster)
LCFAs [extracellular region]
DDCX [extracellular region]
Sensory Perception (Gallus gallus)
Olfactory Signaling Pathway (Gallus gallus)
odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Gallus gallus)
odorant [extracellular region]
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 [plasma membrane] (Gallus gallus)
odorant:Olfactory receptor [plasma membrane] (Gallus gallus)
OR51B5:ligand [plasma membrane] (Gallus gallus)
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
Signal Transduction (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (q) signalling events (Gallus gallus)
The Ligand:GPCR:Gq complex dissociates (Gallus gallus)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Gallus gallus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of vitamins, nucleosides, and related molecules (Gallus gallus)
Transport of fatty acids (Gallus gallus)
SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Gallus gallus)
LCFAs [extracellular region]
DDCX [extracellular region]
Disease (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
SLC transporter disorders (Homo sapiens)
Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS) (Homo sapiens)
Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol (Homo sapiens)
LCFAs [extracellular region]
DDCX [extracellular region]
Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
Regulation of insulin secretion (Homo sapiens)
Free fatty acids regulate insulin secretion (Homo sapiens)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Homo sapiens)
FFAR1 binds fatty acids (Homo sapiens)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands activate Gq (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Metabolism of proteins (Homo sapiens)
Peptide hormone metabolism (Homo sapiens)
Incretin synthesis, secretion, and inactivation (Homo sapiens)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (Homo sapiens)
Glucagon-like Peptide 1 is secreted from intestinal L cells (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (Homo sapiens)
Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Sensory Perception (Homo sapiens)
Olfactory Signaling Pathway (Homo sapiens)
GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 (Homo sapiens)
odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 [plasma membrane] (Homo sapiens)
odorant:Olfactory receptor [plasma membrane] (Homo sapiens)
OR51B5:ligand [plasma membrane] (Homo sapiens)
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 [plasma membrane] (Homo sapiens)
odorant:Olfactory receptor [plasma membrane] (Homo sapiens)
OR51B5:ligand [plasma membrane] (Homo sapiens)
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Homo sapiens)
odorant [extracellular region]
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 [plasma membrane] (Homo sapiens)
odorant:Olfactory receptor [plasma membrane] (Homo sapiens)
OR51B5:ligand [plasma membrane] (Homo sapiens)
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 (Homo sapiens)
odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 [plasma membrane] (Homo sapiens)
odorant:Olfactory receptor [plasma membrane] (Homo sapiens)
OR51B5:ligand [plasma membrane] (Homo sapiens)
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
odorant:Olfactory receptor [plasma membrane] (Homo sapiens)
OR51B5:ligand [plasma membrane] (Homo sapiens)
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Free fatty acid receptors (Homo sapiens)
Receptor FFAR1 binds free fatty acids (Homo sapiens)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of fatty acids (Homo sapiens)
SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Homo sapiens)
LCFAs [extracellular region]
DDCX [extracellular region]
Metabolism (Mus musculus)
Integration of energy metabolism (Mus musculus)
Regulation of insulin secretion (Mus musculus)
Free fatty acids regulate insulin secretion (Mus musculus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Mus musculus)
FFAR1 binds fatty acids (Mus musculus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands activate Gq (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Metabolism of proteins (Mus musculus)
Peptide hormone metabolism (Mus musculus)
Incretin synthesis, secretion, and inactivation (Mus musculus)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (Mus musculus)
Glucagon-like Peptide 1 is secreted from intestinal L cells (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (Mus musculus)
Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Sensory Perception (Mus musculus)
Olfactory Signaling Pathway (Mus musculus)
odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Mus musculus)
odorant [extracellular region]
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 [plasma membrane] (Mus musculus)
odorant:Olfactory receptor [plasma membrane] (Mus musculus)
OR51B5:ligand [plasma membrane] (Mus musculus)
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (q) signalling events (Mus musculus)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Mus musculus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Mus musculus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
GPCR ligand binding (Mus musculus)
Class A/1 (Rhodopsin-like receptors) (Mus musculus)
Free fatty acid receptors (Mus musculus)
Receptor FFAR1 binds free fatty acids (Mus musculus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of vitamins, nucleosides, and related molecules (Mus musculus)
Transport of fatty acids (Mus musculus)
SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Mus musculus)
LCFAs [extracellular region]
DDCX [extracellular region]
Metabolism (Rattus norvegicus)
Integration of energy metabolism (Rattus norvegicus)
Regulation of insulin secretion (Rattus norvegicus)
Free fatty acids regulate insulin secretion (Rattus norvegicus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Rattus norvegicus)
FFAR1 binds fatty acids (Rattus norvegicus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands activate Gq (Rattus norvegicus)
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Metabolism of proteins (Rattus norvegicus)
Peptide hormone metabolism (Rattus norvegicus)
Incretin synthesis, secretion, and inactivation (Rattus norvegicus)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (Rattus norvegicus)
Glucagon-like Peptide 1 is secreted from intestinal L cells (Rattus norvegicus)
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (Rattus norvegicus)
Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Rattus norvegicus)
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Signal Transduction (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (q) signalling events (Rattus norvegicus)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
GPCR ligand binding (Rattus norvegicus)
Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
Free fatty acid receptors (Rattus norvegicus)
Receptor FFAR1 binds free fatty acids (Rattus norvegicus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of vitamins, nucleosides, and related molecules (Rattus norvegicus)
Transport of fatty acids (Rattus norvegicus)
SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Rattus norvegicus)
LCFAs [extracellular region]
DDCX [extracellular region]
Transport of small molecules (Saccharomyces cerevisiae)
SLC-mediated transmembrane transport (Saccharomyces cerevisiae)
Transport of vitamins, nucleosides, and related molecules (Saccharomyces cerevisiae)
Transport of fatty acids (Saccharomyces cerevisiae)
SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Saccharomyces cerevisiae)
LCFAs [extracellular region]
DDCX [extracellular region]
Sensory Perception (Sus scrofa)
Olfactory Signaling Pathway (Sus scrofa)
odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Sus scrofa)
odorant [extracellular region]
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 [plasma membrane] (Sus scrofa)
odorant:Olfactory receptor [plasma membrane] (Sus scrofa)
OR51B5:ligand [plasma membrane] (Sus scrofa)
Ligand of OR51B5 [extracellular region]
DDCX [extracellular region]
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (q) signalling events (Sus scrofa)
The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Sus scrofa)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of vitamins, nucleosides, and related molecules (Sus scrofa)
Transport of fatty acids (Sus scrofa)
SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Sus scrofa)
LCFAs [extracellular region]
DDCX [extracellular region]
Signal Transduction (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (q) signalling events (Xenopus tropicalis)
The Ligand:GPCR:Gq complex dissociates (Xenopus tropicalis)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Xenopus tropicalis)
FFAR1 ligands [extracellular region]
DDCX [extracellular region]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of vitamins, nucleosides, and related molecules (Xenopus tropicalis)
Transport of fatty acids (Xenopus tropicalis)
SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Xenopus tropicalis)
LCFAs [extracellular region]
DDCX [extracellular region]
External Reference Information
External Reference
dodecanoic acid [ChEBI:30805]
Participates
as a member of
Ligand of OR51B5 [extracellular region]
FFAR1 ligands [extracellular region]
as a candidate of
LCFAs [extracellular region]
Other forms of this molecule
DDCX [endoplasmic reticulum lumen]
DDCX [cytosol]
DDCX [lysosomal lumen]
Cross References
Guide to Pharmacology - Ligands
5534
COMPOUND
C02679
PubChem Substance
8145220
HMDB Metabolite
HMDB0000638
ZINC
000001529498
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