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D-Trp [extracellular region]
Stable Identifier
R-ALL-444605
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
D-tryptophan
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Mus musculus
Rattus norvegicus
Sus scrofa
Expand all
Sensory Perception (Bos taurus)
Sensory perception of taste (Bos taurus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Bos taurus)
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Bos taurus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (i) signalling events (Bos taurus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
GPCR ligand binding (Bos taurus)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Bos taurus)
T1R2/T1R3 dimer is a sweet taste receptor (Bos taurus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Sensory Perception (Canis familiaris)
Sensory perception of taste (Canis familiaris)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Canis familiaris)
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Canis familiaris)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Canis familiaris)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Sensory Perception (Danio rerio)
Sensory perception of taste (Danio rerio)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Danio rerio)
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Danio rerio)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Danio rerio)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Signal Transduction (Danio rerio)
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (i) signalling events (Danio rerio)
Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Danio rerio)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Danio rerio)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
GPCR ligand binding (Danio rerio)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Danio rerio)
T1R2/T1R3 dimer is a sweet taste receptor (Danio rerio)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Danio rerio)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Sensory Perception (Homo sapiens)
Sensory perception of taste (Homo sapiens)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Homo sapiens)
GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GTP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 (Homo sapiens)
TAS1R2:TAS1R3:Sweet compound:GNAT3:GTP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
GPCR ligand binding (Homo sapiens)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Homo sapiens)
T1R2/T1R3 dimer is a sweet taste receptor (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Sensory Perception (Mus musculus)
Sensory perception of taste (Mus musculus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Mus musculus)
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Mus musculus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (i) signalling events (Mus musculus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
GPCR ligand binding (Mus musculus)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Mus musculus)
T1R2/T1R3 dimer is a sweet taste receptor (Mus musculus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Sensory Perception (Rattus norvegicus)
Sensory perception of taste (Rattus norvegicus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Rattus norvegicus)
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Rattus norvegicus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Rattus norvegicus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Rattus norvegicus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Signal Transduction (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (i) signalling events (Rattus norvegicus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Rattus norvegicus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Rattus norvegicus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
GPCR ligand binding (Rattus norvegicus)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Rattus norvegicus)
T1R2/T1R3 dimer is a sweet taste receptor (Rattus norvegicus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Rattus norvegicus)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Sensory Perception (Sus scrofa)
Sensory perception of taste (Sus scrofa)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Sus scrofa)
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Sus scrofa)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (i) signalling events (Sus scrofa)
Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
GPCR ligand binding (Sus scrofa)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Sus scrofa)
T1R2/T1R3 dimer is a sweet taste receptor (Sus scrofa)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
D-Trp [extracellular region]
External Reference Information
External Reference
D-tryptophan [ChEBI:16296]
Participates
as a member of
Sweet taste compounds [extracellular region]
Cross References
HMDB Metabolite
HMDB0013609
ZINC
000000083317
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