Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
PGD2 [extracellular region]
Stable Identifier
R-ALL-416911
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
prostaglandin D2
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (i) signalling events (Bos taurus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
PTGDR2:PGD2 [plasma membrane] (Bos taurus)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
PTGDR2:PGD2 [plasma membrane] (Bos taurus)
PGD2 [extracellular region]
GPCR ligand binding (Bos taurus)
Class A/1 (Rhodopsin-like receptors) (Bos taurus)
Eicosanoid ligand-binding receptors (Bos taurus)
Prostanoid ligand receptors (Bos taurus)
DP1 receptor can bind PGD2 (Bos taurus)
PGD2 [extracellular region]
PTGDR:PGD2 [plasma membrane] (Bos taurus)
PGD2 [extracellular region]
DP2 receptor can bind PGD2 (Bos taurus)
PGD2 [extracellular region]
PTGDR2:PGD2 [plasma membrane] (Bos taurus)
PGD2 [extracellular region]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of vitamins, nucleosides, and related molecules (Bos taurus)
Transport of organic anions (Bos taurus)
SLCO2A1 transports PGT substrates from extracellular region to cytosol (Bos taurus)
PGT substrates [extracellular region]
PGD2 [extracellular region]
Signal Transduction (Caenorhabditis elegans)
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (i) signalling events (Caenorhabditis elegans)
Liganded Gi-activating GPCR acts as a GEF for Gi (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
PGD2 [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
PGD2 [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
PGD2 [extracellular region]
GPCR ligand binding (Caenorhabditis elegans)
Class A/1 (Rhodopsin-like receptors) (Caenorhabditis elegans)
Eicosanoid ligand-binding receptors (Caenorhabditis elegans)
Prostanoid ligand receptors (Caenorhabditis elegans)
DP2 receptor can bind PGD2 (Caenorhabditis elegans)
PGD2 [extracellular region]
PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
PGD2 [extracellular region]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of vitamins, nucleosides, and related molecules (Caenorhabditis elegans)
Transport of organic anions (Caenorhabditis elegans)
SLCO2A1 transports PGT substrates from extracellular region to cytosol (Caenorhabditis elegans)
PGT substrates [extracellular region]
PGD2 [extracellular region]
Signal Transduction (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (i) signalling events (Canis familiaris)
Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
PTGDR2:PGD2 [plasma membrane] (Canis familiaris)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
PTGDR2:PGD2 [plasma membrane] (Canis familiaris)
PGD2 [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
PTGDR2:PGD2 [plasma membrane] (Canis familiaris)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
PTGDR2:PGD2 [plasma membrane] (Canis familiaris)
PGD2 [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
PTGDR2:PGD2 [plasma membrane] (Canis familiaris)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
PTGDR2:PGD2 [plasma membrane] (Canis familiaris)
PGD2 [extracellular region]
G alpha (s) signalling events (Canis familiaris)
Liganded Gs-activating GPCR acts as a GEF for Gs (Canis familiaris)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Canis familiaris)
PTGDR:PGD2 [plasma membrane] (Canis familiaris)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Canis familiaris)
PTGDR:PGD2 [plasma membrane] (Canis familiaris)
PGD2 [extracellular region]
GPCR ligand binding (Canis familiaris)
Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
Eicosanoid ligand-binding receptors (Canis familiaris)
Prostanoid ligand receptors (Canis familiaris)
DP1 receptor can bind PGD2 (Canis familiaris)
PGD2 [extracellular region]
PTGDR:PGD2 [plasma membrane] (Canis familiaris)
PGD2 [extracellular region]
DP2 receptor can bind PGD2 (Canis familiaris)
PGD2 [extracellular region]
PTGDR2:PGD2 [plasma membrane] (Canis familiaris)
PGD2 [extracellular region]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of vitamins, nucleosides, and related molecules (Canis familiaris)
Transport of organic anions (Canis familiaris)
SLCO2A1 transports PGT substrates from extracellular region to cytosol (Canis familiaris)
PGT substrates [extracellular region]
PGD2 [extracellular region]
Signal Transduction (Danio rerio)
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (i) signalling events (Danio rerio)
Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
PTGDR2:PGD2 [plasma membrane] (Danio rerio)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
PTGDR2:PGD2 [plasma membrane] (Danio rerio)
PGD2 [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
PTGDR2:PGD2 [plasma membrane] (Danio rerio)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
PTGDR2:PGD2 [plasma membrane] (Danio rerio)
PGD2 [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
PTGDR2:PGD2 [plasma membrane] (Danio rerio)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
PTGDR2:PGD2 [plasma membrane] (Danio rerio)
PGD2 [extracellular region]
GPCR ligand binding (Danio rerio)
Class A/1 (Rhodopsin-like receptors) (Danio rerio)
Eicosanoid ligand-binding receptors (Danio rerio)
Prostanoid ligand receptors (Danio rerio)
DP2 receptor can bind PGD2 (Danio rerio)
PGD2 [extracellular region]
PTGDR2:PGD2 [plasma membrane] (Danio rerio)
PGD2 [extracellular region]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of vitamins, nucleosides, and related molecules (Danio rerio)
Transport of organic anions (Danio rerio)
SLCO2A1 transports PGT substrates from extracellular region to cytosol (Danio rerio)
PGT substrates [extracellular region]
PGD2 [extracellular region]
Signal Transduction (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (i) signalling events (Drosophila melanogaster)
Liganded Gi-activating GPCR acts as a GEF for Gi (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
PTGDR2:PGD2 [plasma membrane] (Drosophila melanogaster)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
PTGDR2:PGD2 [plasma membrane] (Drosophila melanogaster)
PGD2 [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
PTGDR2:PGD2 [plasma membrane] (Drosophila melanogaster)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
PTGDR2:PGD2 [plasma membrane] (Drosophila melanogaster)
PGD2 [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
PTGDR2:PGD2 [plasma membrane] (Drosophila melanogaster)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
PTGDR2:PGD2 [plasma membrane] (Drosophila melanogaster)
PGD2 [extracellular region]
G alpha (s) signalling events (Drosophila melanogaster)
Liganded Gs-activating GPCR acts as a GEF for Gs (Drosophila melanogaster)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Drosophila melanogaster)
PTGDR:PGD2 [plasma membrane] (Drosophila melanogaster)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Drosophila melanogaster)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Drosophila melanogaster)
PTGDR:PGD2 [plasma membrane] (Drosophila melanogaster)
PGD2 [extracellular region]
GPCR ligand binding (Drosophila melanogaster)
Class A/1 (Rhodopsin-like receptors) (Drosophila melanogaster)
Eicosanoid ligand-binding receptors (Drosophila melanogaster)
Prostanoid ligand receptors (Drosophila melanogaster)
DP1 receptor can bind PGD2 (Drosophila melanogaster)
PGD2 [extracellular region]
PTGDR:PGD2 [plasma membrane] (Drosophila melanogaster)
PGD2 [extracellular region]
DP2 receptor can bind PGD2 (Drosophila melanogaster)
PGD2 [extracellular region]
PTGDR2:PGD2 [plasma membrane] (Drosophila melanogaster)
PGD2 [extracellular region]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of vitamins, nucleosides, and related molecules (Drosophila melanogaster)
Transport of organic anions (Drosophila melanogaster)
SLCO2A1 transports PGT substrates from extracellular region to cytosol (Drosophila melanogaster)
PGT substrates [extracellular region]
PGD2 [extracellular region]
Signal Transduction (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (i) signalling events (Gallus gallus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Gallus gallus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
PTGDR2:PGD2 [plasma membrane] (Gallus gallus)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
PTGDR2:PGD2 [plasma membrane] (Gallus gallus)
PGD2 [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
PTGDR2:PGD2 [plasma membrane] (Gallus gallus)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
PTGDR2:PGD2 [plasma membrane] (Gallus gallus)
PGD2 [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
PTGDR2:PGD2 [plasma membrane] (Gallus gallus)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
PTGDR2:PGD2 [plasma membrane] (Gallus gallus)
PGD2 [extracellular region]
G alpha (s) signalling events (Gallus gallus)
Liganded Gs-activating GPCR acts as a GEF for Gs (Gallus gallus)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Gallus gallus)
PTGDR:PGD2 [plasma membrane] (Gallus gallus)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Gallus gallus)
PTGDR:PGD2 [plasma membrane] (Gallus gallus)
PGD2 [extracellular region]
GPCR ligand binding (Gallus gallus)
Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
Eicosanoid ligand-binding receptors (Gallus gallus)
Prostanoid ligand receptors (Gallus gallus)
DP1 receptor can bind PGD2 (Gallus gallus)
PGD2 [extracellular region]
PTGDR:PGD2 [plasma membrane] (Gallus gallus)
PGD2 [extracellular region]
DP2 receptor can bind PGD2 (Gallus gallus)
PGD2 [extracellular region]
PTGDR2:PGD2 [plasma membrane] (Gallus gallus)
PGD2 [extracellular region]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of vitamins, nucleosides, and related molecules (Gallus gallus)
Transport of organic anions (Gallus gallus)
SLCO2A1 transports PGT substrates from extracellular region to cytosol (Gallus gallus)
PGT substrates [extracellular region]
PGD2 [extracellular region]
Disease (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
SLC transporter disorders (Homo sapiens)
Defective SLCO2A1 causes primary, autosomal recessive hypertrophic osteoarthropathy 2 (PHOAR2) (Homo sapiens)
Defective SLCO2A1 does not transport PGT substrates from extracellular region to cytosol (Homo sapiens)
PGT substrates [extracellular region]
PGD2 [extracellular region]
Infectious disease (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)
ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTGDR:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
PTGDR2:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
PTGDR2:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
PTGDR2:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
PTGDR2:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
PTGDR2:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
PTGDR2:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTGDR:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTGDR:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTGDR:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTGDR:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTGDR:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
Ligands of GPCRs that activate Gs [extracellular region] (Homo sapiens)
PGD2 [extracellular region]
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Eicosanoid ligand-binding receptors (Homo sapiens)
Prostanoid ligand receptors (Homo sapiens)
DP1 receptor can bind PGD2 (Homo sapiens)
PGD2 [extracellular region]
PTGDR:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
DP2 receptor can bind PGD2 (Homo sapiens)
PGD2 [extracellular region]
PTGDR2:PGD2 [plasma membrane] (Homo sapiens)
PGD2 [extracellular region]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of organic anions (Homo sapiens)
SLCO2A1 transports PGT substrates from extracellular region to cytosol (Homo sapiens)
PGT substrates [extracellular region]
PGD2 [extracellular region]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (i) signalling events (Mus musculus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
PTGDR2:PGD2 [plasma membrane] (Mus musculus)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
PTGDR2:PGD2 [plasma membrane] (Mus musculus)
PGD2 [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
PTGDR2:PGD2 [plasma membrane] (Mus musculus)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
PTGDR2:PGD2 [plasma membrane] (Mus musculus)
PGD2 [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
PTGDR2:PGD2 [plasma membrane] (Mus musculus)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
PTGDR2:PGD2 [plasma membrane] (Mus musculus)
PGD2 [extracellular region]
G alpha (s) signalling events (Mus musculus)
Liganded Gs-activating GPCR acts as a GEF for Gs (Mus musculus)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Mus musculus)
PTGDR:PGD2 [plasma membrane] (Mus musculus)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Mus musculus)
PTGDR:PGD2 [plasma membrane] (Mus musculus)
PGD2 [extracellular region]
GPCR ligand binding (Mus musculus)
Class A/1 (Rhodopsin-like receptors) (Mus musculus)
Eicosanoid ligand-binding receptors (Mus musculus)
Prostanoid ligand receptors (Mus musculus)
DP1 receptor can bind PGD2 (Mus musculus)
PGD2 [extracellular region]
PTGDR:PGD2 [plasma membrane] (Mus musculus)
PGD2 [extracellular region]
DP2 receptor can bind PGD2 (Mus musculus)
PGD2 [extracellular region]
PTGDR2:PGD2 [plasma membrane] (Mus musculus)
PGD2 [extracellular region]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of vitamins, nucleosides, and related molecules (Mus musculus)
Transport of organic anions (Mus musculus)
SLCO2A1 transports PGT substrates from extracellular region to cytosol (Mus musculus)
PGT substrates [extracellular region]
PGD2 [extracellular region]
Signal Transduction (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (i) signalling events (Rattus norvegicus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
PTGDR2:PGD2 [plasma membrane] (Rattus norvegicus)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
PTGDR2:PGD2 [plasma membrane] (Rattus norvegicus)
PGD2 [extracellular region]
GPCR ligand binding (Rattus norvegicus)
Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
Eicosanoid ligand-binding receptors (Rattus norvegicus)
Prostanoid ligand receptors (Rattus norvegicus)
DP1 receptor can bind PGD2 (Rattus norvegicus)
PGD2 [extracellular region]
PTGDR:PGD2 [plasma membrane] (Rattus norvegicus)
PGD2 [extracellular region]
DP2 receptor can bind PGD2 (Rattus norvegicus)
PGD2 [extracellular region]
PTGDR2:PGD2 [plasma membrane] (Rattus norvegicus)
PGD2 [extracellular region]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of vitamins, nucleosides, and related molecules (Rattus norvegicus)
Transport of organic anions (Rattus norvegicus)
SLCO2A1 transports PGT substrates from extracellular region to cytosol (Rattus norvegicus)
PGT substrates [extracellular region]
PGD2 [extracellular region]
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (i) signalling events (Sus scrofa)
Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
PTGDR2:PGD2 [plasma membrane] (Sus scrofa)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
PTGDR2:PGD2 [plasma membrane] (Sus scrofa)
PGD2 [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
PTGDR2:PGD2 [plasma membrane] (Sus scrofa)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
PTGDR2:PGD2 [plasma membrane] (Sus scrofa)
PGD2 [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
PTGDR2:PGD2 [plasma membrane] (Sus scrofa)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
PTGDR2:PGD2 [plasma membrane] (Sus scrofa)
PGD2 [extracellular region]
GPCR ligand binding (Sus scrofa)
Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
Eicosanoid ligand-binding receptors (Sus scrofa)
Prostanoid ligand receptors (Sus scrofa)
DP2 receptor can bind PGD2 (Sus scrofa)
PGD2 [extracellular region]
PTGDR2:PGD2 [plasma membrane] (Sus scrofa)
PGD2 [extracellular region]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of vitamins, nucleosides, and related molecules (Sus scrofa)
Transport of organic anions (Sus scrofa)
SLCO2A1 transports PGT substrates from extracellular region to cytosol (Sus scrofa)
PGT substrates [extracellular region]
PGD2 [extracellular region]
Signal Transduction (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (i) signalling events (Xenopus tropicalis)
Liganded Gi-activating GPCR acts as a GEF for Gi (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
PTGDR2:PGD2 [plasma membrane] (Xenopus tropicalis)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
PTGDR2:PGD2 [plasma membrane] (Xenopus tropicalis)
PGD2 [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
PTGDR2:PGD2 [plasma membrane] (Xenopus tropicalis)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
PTGDR2:PGD2 [plasma membrane] (Xenopus tropicalis)
PGD2 [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
PTGDR2:PGD2 [plasma membrane] (Xenopus tropicalis)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
PTGDR2:PGD2 [plasma membrane] (Xenopus tropicalis)
PGD2 [extracellular region]
G alpha (s) signalling events (Xenopus tropicalis)
Liganded Gs-activating GPCR acts as a GEF for Gs (Xenopus tropicalis)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Xenopus tropicalis)
PTGDR:PGD2 [plasma membrane] (Xenopus tropicalis)
PGD2 [extracellular region]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Xenopus tropicalis)
PTGDR:PGD2 [plasma membrane] (Xenopus tropicalis)
PGD2 [extracellular region]
GPCR ligand binding (Xenopus tropicalis)
Class A/1 (Rhodopsin-like receptors) (Xenopus tropicalis)
Eicosanoid ligand-binding receptors (Xenopus tropicalis)
Prostanoid ligand receptors (Xenopus tropicalis)
DP1 receptor can bind PGD2 (Xenopus tropicalis)
PGD2 [extracellular region]
PTGDR:PGD2 [plasma membrane] (Xenopus tropicalis)
PGD2 [extracellular region]
DP2 receptor can bind PGD2 (Xenopus tropicalis)
PGD2 [extracellular region]
PTGDR2:PGD2 [plasma membrane] (Xenopus tropicalis)
PGD2 [extracellular region]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of vitamins, nucleosides, and related molecules (Xenopus tropicalis)
Transport of organic anions (Xenopus tropicalis)
SLCO2A1 transports PGT substrates from extracellular region to cytosol (Xenopus tropicalis)
PGT substrates [extracellular region]
PGD2 [extracellular region]
External Reference Information
External Reference
prostaglandin D2 [ChEBI:15555]
Participant Of
hasMember
Ligands of GPCRs that activate Gs [extracellular region]
PGT substrates [extracellular region]
input
DP1 receptor can bind PGD2
DP1 receptor can bind PGD2
DP1 receptor can bind PGD2
DP1 receptor can bind PGD2
DP1 receptor can bind PGD2
DP1 receptor can bind PGD2
DP1 receptor can bind PGD2
DP1 receptor can bind PGD2
DP2 receptor can bind PGD2
DP2 receptor can bind PGD2
DP2 receptor can bind PGD2
DP2 receptor can bind PGD2
DP2 receptor can bind PGD2
DP2 receptor can bind PGD2
DP2 receptor can bind PGD2
DP2 receptor can bind PGD2
DP2 receptor can bind PGD2
DP2 receptor can bind PGD2
DP2 receptor can bind PGD2
hasComponent
PTGDR2:PGD2 [plasma membrane]
PTGDR2:PGD2 [plasma membrane]
PTGDR2:PGD2 [plasma membrane]
PTGDR2:PGD2 [plasma membrane]
PTGDR2:PGD2 [plasma membrane]
PTGDR2:PGD2 [plasma membrane]
PTGDR2:PGD2 [plasma membrane]
PTGDR2:PGD2 [plasma membrane]
PTGDR2:PGD2 [plasma membrane]
PTGDR2:PGD2 [plasma membrane]
PTGDR2:PGD2 [plasma membrane]
PTGDR:PGD2 [plasma membrane]
PTGDR:PGD2 [plasma membrane]
PTGDR:PGD2 [plasma membrane]
PTGDR:PGD2 [plasma membrane]
PTGDR:PGD2 [plasma membrane]
PTGDR:PGD2 [plasma membrane]
PTGDR:PGD2 [plasma membrane]
PTGDR:PGD2 [plasma membrane]
Other forms of this molecule
PGD2 [endoplasmic reticulum lumen]
PGD2 [cytosol]
Cross References
COMPOUND
C00696
HMDB Metabolite
HMDB0001403
© 2020
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
