Reactome | CAF [endoplasmic reticulum lumen]

CAF [endoplasmic reticulum lumen]

Stable Identifier

R-ALL-40727

Type

Chemical Compound [SimpleEntity]

Compartment

endoplasmic reticulum lumen

Synonyms

caffeine

Locations in the PathwayBrowser

for Species:

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Metabolism (Bos taurus)

- Biological oxidations (Bos taurus)
  - Phase I - Functionalization of compounds (Bos taurus)
    - Cytochrome P450 - arranged by substrate type (Bos taurus)
      - Xenobiotics (Bos taurus)
        
        Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Bos taurus)
        
        N-atom dealkylation of caffeine (Bos taurus)
        
        CAF [endoplasmic reticulum lumen]

Metabolism (Danio rerio)

- Biological oxidations (Danio rerio)
  - Phase I - Functionalization of compounds (Danio rerio)
    - Cytochrome P450 - arranged by substrate type (Danio rerio)
      - Xenobiotics (Danio rerio)
        
        Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Danio rerio)
        
        N-atom dealkylation of caffeine (Danio rerio)
        
        CAF [endoplasmic reticulum lumen]

Metabolism (Gallus gallus)

- Biological oxidations (Gallus gallus)
  - Phase I - Functionalization of compounds (Gallus gallus)
    - Cytochrome P450 - arranged by substrate type (Gallus gallus)
      - Xenobiotics (Gallus gallus)
        
        Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Gallus gallus)
        
        N-atom dealkylation of caffeine (Gallus gallus)
        
        CAF [endoplasmic reticulum lumen]

Metabolism (Homo sapiens)

- Biological oxidations (Homo sapiens)
  - Phase I - Functionalization of compounds (Homo sapiens)
    - Cytochrome P450 - arranged by substrate type (Homo sapiens)
      - Xenobiotics (Homo sapiens)
        
        Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Homo sapiens)
        
        N-atom dealkylation of caffeine (Homo sapiens)
        
        CAF [endoplasmic reticulum lumen]

Metabolism (Mus musculus)

- Biological oxidations (Mus musculus)
  - Phase I - Functionalization of compounds (Mus musculus)
    - Cytochrome P450 - arranged by substrate type (Mus musculus)
      - Xenobiotics (Mus musculus)
        
        Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Mus musculus)
        
        N-atom dealkylation of caffeine (Mus musculus)
        
        CAF [endoplasmic reticulum lumen]

Metabolism (Rattus norvegicus)

- Biological oxidations (Rattus norvegicus)
  - Phase I - Functionalization of compounds (Rattus norvegicus)
    - Cytochrome P450 - arranged by substrate type (Rattus norvegicus)
      - Xenobiotics (Rattus norvegicus)
        
        Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Rattus norvegicus)
        
        N-atom dealkylation of caffeine (Rattus norvegicus)
        
        CAF [endoplasmic reticulum lumen]

Metabolism (Sus scrofa)

- Biological oxidations (Sus scrofa)
  - Phase I - Functionalization of compounds (Sus scrofa)
    - Cytochrome P450 - arranged by substrate type (Sus scrofa)
      - Xenobiotics (Sus scrofa)
        
        Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Sus scrofa)
        
        N-atom dealkylation of caffeine (Sus scrofa)
        
        CAF [endoplasmic reticulum lumen]

Metabolism (Xenopus tropicalis)

- Biological oxidations (Xenopus tropicalis)
  - Phase I - Functionalization of compounds (Xenopus tropicalis)
    - Cytochrome P450 - arranged by substrate type (Xenopus tropicalis)
      - Xenobiotics (Xenopus tropicalis)
        
        Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Xenopus tropicalis)
        
        N-atom dealkylation of caffeine (Xenopus tropicalis)
        
        CAF [endoplasmic reticulum lumen]

External Reference Information

External Reference

caffeine [ChEBI:27732]

Participates

as an input of

Other forms of this molecule

Caffeine [extracellular region]

Cross References

COMPOUND

C07481

PubChem Substance

8144467

HMDB Metabolite

HMDB0001847

ZINC

000000001084

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