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b-Ala [extracellular region]
Stable Identifier
R-ALL-352021
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
3-aminopropionic acid, beta-alanine, 3-Aminopropanoate
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter release cycle (Bos taurus)
GABA synthesis, release, reuptake and degradation (Bos taurus)
Reuptake of GABA (Bos taurus)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Bos taurus)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of bile salts and organic acids, metal ions and amine compounds (Bos taurus)
Na+/Cl- dependent neurotransmitter transporters (Bos taurus)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Bos taurus)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Bos taurus)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Bos taurus)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Bos taurus)
Amino acid transport across the plasma membrane (Bos taurus)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Bos taurus)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Bos taurus)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Bos taurus)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of bile salts and organic acids, metal ions and amine compounds (Caenorhabditis elegans)
Na+/Cl- dependent neurotransmitter transporters (Caenorhabditis elegans)
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Caenorhabditis elegans)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Caenorhabditis elegans)
Amino acid transport across the plasma membrane (Caenorhabditis elegans)
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Caenorhabditis elegans)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
Neuronal System (Canis familiaris)
Transmission across Chemical Synapses (Canis familiaris)
Neurotransmitter release cycle (Canis familiaris)
GABA synthesis, release, reuptake and degradation (Canis familiaris)
Reuptake of GABA (Canis familiaris)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Canis familiaris)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of bile salts and organic acids, metal ions and amine compounds (Canis familiaris)
Na+/Cl- dependent neurotransmitter transporters (Canis familiaris)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Canis familiaris)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Canis familiaris)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Canis familiaris)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Canis familiaris)
Amino acid transport across the plasma membrane (Canis familiaris)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Canis familiaris)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Canis familiaris)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Canis familiaris)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Neuronal System (Danio rerio)
Transmission across Chemical Synapses (Danio rerio)
Neurotransmitter release cycle (Danio rerio)
GABA synthesis, release, reuptake and degradation (Danio rerio)
Reuptake of GABA (Danio rerio)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Danio rerio)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of bile salts and organic acids, metal ions and amine compounds (Danio rerio)
Na+/Cl- dependent neurotransmitter transporters (Danio rerio)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Danio rerio)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Danio rerio)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Danio rerio)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Danio rerio)
Amino acid transport across the plasma membrane (Danio rerio)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Danio rerio)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Danio rerio)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Danio rerio)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of bile salts and organic acids, metal ions and amine compounds (Drosophila melanogaster)
Na+/Cl- dependent neurotransmitter transporters (Drosophila melanogaster)
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Drosophila melanogaster)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Drosophila melanogaster)
Amino acid transport across the plasma membrane (Drosophila melanogaster)
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Drosophila melanogaster)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
Neuronal System (Gallus gallus)
Transmission across Chemical Synapses (Gallus gallus)
Neurotransmitter release cycle (Gallus gallus)
GABA synthesis, release, reuptake and degradation (Gallus gallus)
Reuptake of GABA (Gallus gallus)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Gallus gallus)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of bile salts and organic acids, metal ions and amine compounds (Gallus gallus)
Na+/Cl- dependent neurotransmitter transporters (Gallus gallus)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Gallus gallus)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Gallus gallus)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Gallus gallus)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Gallus gallus)
Amino acid transport across the plasma membrane (Gallus gallus)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Gallus gallus)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Gallus gallus)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Gallus gallus)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Disease (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
SLC transporter disorders (Homo sapiens)
Variant SLC6A14 may confer susceptibility towards obesity (Homo sapiens)
Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Homo sapiens)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter release cycle (Homo sapiens)
GABA synthesis, release, reuptake and degradation (Homo sapiens)
Reuptake of GABA (Homo sapiens)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Homo sapiens)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Na+/Cl- dependent neurotransmitter transporters (Homo sapiens)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Homo sapiens)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Homo sapiens)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Homo sapiens)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Amino acid transport across the plasma membrane (Homo sapiens)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Homo sapiens)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Homo sapiens)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Homo sapiens)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Neuronal System (Mus musculus)
Transmission across Chemical Synapses (Mus musculus)
Neurotransmitter release cycle (Mus musculus)
GABA synthesis, release, reuptake and degradation (Mus musculus)
Reuptake of GABA (Mus musculus)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Mus musculus)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of bile salts and organic acids, metal ions and amine compounds (Mus musculus)
Na+/Cl- dependent neurotransmitter transporters (Mus musculus)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Mus musculus)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Mus musculus)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Mus musculus)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Mus musculus)
Amino acid transport across the plasma membrane (Mus musculus)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Mus musculus)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Mus musculus)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Mus musculus)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Neuronal System (Plasmodium falciparum)
Transmission across Chemical Synapses (Plasmodium falciparum)
Neurotransmitter release cycle (Plasmodium falciparum)
GABA synthesis, release, reuptake and degradation (Plasmodium falciparum)
Reuptake of GABA (Plasmodium falciparum)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Plasmodium falciparum)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
Transport of small molecules (Plasmodium falciparum)
SLC-mediated transmembrane transport (Plasmodium falciparum)
Transport of bile salts and organic acids, metal ions and amine compounds (Plasmodium falciparum)
Na+/Cl- dependent neurotransmitter transporters (Plasmodium falciparum)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Plasmodium falciparum)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Plasmodium falciparum)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Plasmodium falciparum)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Plasmodium falciparum)
Amino acid transport across the plasma membrane (Plasmodium falciparum)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Plasmodium falciparum)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Plasmodium falciparum)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Plasmodium falciparum)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Neuronal System (Rattus norvegicus)
Transmission across Chemical Synapses (Rattus norvegicus)
Neurotransmitter release cycle (Rattus norvegicus)
GABA synthesis, release, reuptake and degradation (Rattus norvegicus)
Reuptake of GABA (Rattus norvegicus)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Rattus norvegicus)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of bile salts and organic acids, metal ions and amine compounds (Rattus norvegicus)
Na+/Cl- dependent neurotransmitter transporters (Rattus norvegicus)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Rattus norvegicus)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Rattus norvegicus)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Rattus norvegicus)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Rattus norvegicus)
Amino acid transport across the plasma membrane (Rattus norvegicus)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Rattus norvegicus)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Rattus norvegicus)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Rattus norvegicus)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Neuronal System (Sus scrofa)
Transmission across Chemical Synapses (Sus scrofa)
Neurotransmitter release cycle (Sus scrofa)
GABA synthesis, release, reuptake and degradation (Sus scrofa)
Reuptake of GABA (Sus scrofa)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Sus scrofa)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of bile salts and organic acids, metal ions and amine compounds (Sus scrofa)
Na+/Cl- dependent neurotransmitter transporters (Sus scrofa)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Sus scrofa)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Sus scrofa)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Sus scrofa)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Sus scrofa)
Amino acid transport across the plasma membrane (Sus scrofa)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Sus scrofa)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Sus scrofa)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Sus scrofa)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Neuronal System (Xenopus tropicalis)
Transmission across Chemical Synapses (Xenopus tropicalis)
Neurotransmitter release cycle (Xenopus tropicalis)
GABA synthesis, release, reuptake and degradation (Xenopus tropicalis)
Reuptake of GABA (Xenopus tropicalis)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Xenopus tropicalis)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of bile salts and organic acids, metal ions and amine compounds (Xenopus tropicalis)
Na+/Cl- dependent neurotransmitter transporters (Xenopus tropicalis)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Xenopus tropicalis)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Xenopus tropicalis)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Xenopus tropicalis)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Xenopus tropicalis)
Amino acid transport across the plasma membrane (Xenopus tropicalis)
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Xenopus tropicalis)
ligands of SLC6A12 (BGT-1) [extracellular region]
b-Ala [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Xenopus tropicalis)
SLC6A14 ligands [extracellular region]
b-Ala [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Xenopus tropicalis)
ligands of SLC6A6 [extracellular region]
b-Ala [extracellular region]
External Reference Information
External Reference
beta-alanine [ChEBI:16958]
Participates
as a member of
SLC6A14 ligands [extracellular region]
ligands of SLC6A6 [extracellular region]
ligands of SLC6A12 (BGT-1) [extracellular region]
Cross References
COMPOUND
C00099
PubChem Substance
8144745
HMDB Metabolite
HMDB0000056
ZINC
000004658555
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