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AdoCbl [mitochondrial matrix]
Stable Identifier
R-ALL-3159297
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
adenosylcobalamin, cobamamide
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of lipids (Bos taurus)
Fatty acid metabolism (Bos taurus)
Mitochondrial Fatty Acid Beta-Oxidation (Bos taurus)
Propionyl-CoA catabolism (Bos taurus)
MUT isomerises L-MM-CoA to SUCC-CoA (Bos taurus)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Bos taurus)
AdoCbl [mitochondrial matrix]
2xMUT:AdoCbl [mitochondrial matrix] (Bos taurus)
AdoCbl [mitochondrial matrix]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Bos taurus)
Cobalamin (Cbl) metabolism (Bos taurus)
MMAA:MUT binds AdoCbl (Bos taurus)
AdoCbl [mitochondrial matrix]
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Bos taurus)
AdoCbl [mitochondrial matrix]
MMAB adenosylates cob(I)alamin (Bos taurus)
AdoCbl [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Metabolism of lipids (Caenorhabditis elegans)
Fatty acid metabolism (Caenorhabditis elegans)
Mitochondrial Fatty Acid Beta-Oxidation (Caenorhabditis elegans)
Propionyl-CoA catabolism (Caenorhabditis elegans)
MUT isomerises L-MM-CoA to SUCC-CoA (Caenorhabditis elegans)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Caenorhabditis elegans)
AdoCbl [mitochondrial matrix]
2xMUT:AdoCbl [mitochondrial matrix] (Caenorhabditis elegans)
AdoCbl [mitochondrial matrix]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Caenorhabditis elegans)
Cobalamin (Cbl) metabolism (Caenorhabditis elegans)
MMAA:MUT binds AdoCbl (Caenorhabditis elegans)
AdoCbl [mitochondrial matrix]
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Caenorhabditis elegans)
AdoCbl [mitochondrial matrix]
MMAB adenosylates cob(I)alamin (Caenorhabditis elegans)
AdoCbl [mitochondrial matrix]
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Mitochondrial Fatty Acid Beta-Oxidation (Canis familiaris)
Propionyl-CoA catabolism (Canis familiaris)
MUT isomerises L-MM-CoA to SUCC-CoA (Canis familiaris)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Canis familiaris)
AdoCbl [mitochondrial matrix]
2xMUT:AdoCbl [mitochondrial matrix] (Canis familiaris)
AdoCbl [mitochondrial matrix]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Canis familiaris)
Cobalamin (Cbl) metabolism (Canis familiaris)
MMAA:MUT binds AdoCbl (Canis familiaris)
AdoCbl [mitochondrial matrix]
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Canis familiaris)
AdoCbl [mitochondrial matrix]
MMAB adenosylates cob(I)alamin (Canis familiaris)
AdoCbl [mitochondrial matrix]
Metabolism (Danio rerio)
Metabolism of lipids (Danio rerio)
Fatty acid metabolism (Danio rerio)
Mitochondrial Fatty Acid Beta-Oxidation (Danio rerio)
Propionyl-CoA catabolism (Danio rerio)
MUT isomerises L-MM-CoA to SUCC-CoA (Danio rerio)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Danio rerio)
AdoCbl [mitochondrial matrix]
2xMUT:AdoCbl [mitochondrial matrix] (Danio rerio)
AdoCbl [mitochondrial matrix]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Danio rerio)
Cobalamin (Cbl) metabolism (Danio rerio)
MMAA:MUT binds AdoCbl (Danio rerio)
AdoCbl [mitochondrial matrix]
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Danio rerio)
AdoCbl [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Dictyostelium discoideum)
Cobalamin (Cbl) metabolism (Dictyostelium discoideum)
MMAB adenosylates cob(I)alamin (Dictyostelium discoideum)
AdoCbl [mitochondrial matrix]
Metabolism (Gallus gallus)
Metabolism of lipids (Gallus gallus)
Fatty acid metabolism (Gallus gallus)
Mitochondrial Fatty Acid Beta-Oxidation (Gallus gallus)
Propionyl-CoA catabolism (Gallus gallus)
MUT isomerises L-MM-CoA to SUCC-CoA (Gallus gallus)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Gallus gallus)
AdoCbl [mitochondrial matrix]
2xMUT:AdoCbl [mitochondrial matrix] (Gallus gallus)
AdoCbl [mitochondrial matrix]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Gallus gallus)
Cobalamin (Cbl) metabolism (Gallus gallus)
MMAA:MUT binds AdoCbl (Gallus gallus)
AdoCbl [mitochondrial matrix]
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Gallus gallus)
AdoCbl [mitochondrial matrix]
MMAB adenosylates cob(I)alamin (Gallus gallus)
AdoCbl [mitochondrial matrix]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Defects in vitamin and cofactor metabolism (Homo sapiens)
Defects in cobalamin (B12) metabolism (Homo sapiens)
Defective MMAA causes MMA, cblA type (Homo sapiens)
Defective MMAA does not protect MUT (Homo sapiens)
AdoCbl [mitochondrial matrix]
Diseases of mitochondrial beta oxidation (Homo sapiens)
Diseases of propionyl-CoA catabolism (Homo sapiens)
Defective MUT causes MMAM (Homo sapiens)
Defective MUT does not isomerise L-MM-CoA to SUCC-CoA (Homo sapiens)
2xMMAA:mutant MUT:AdoCbl [mitochondrial matrix] (Homo sapiens)
mutant MUT:AdoCbl [mitochondrial matrix] (Homo sapiens)
AdoCbl [mitochondrial matrix]
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Mitochondrial Fatty Acid Beta-Oxidation (Homo sapiens)
Propionyl-CoA catabolism (Homo sapiens)
MUT isomerises L-MM-CoA to SUCC-CoA (Homo sapiens)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Homo sapiens)
AdoCbl [mitochondrial matrix]
2xMUT:AdoCbl [mitochondrial matrix] (Homo sapiens)
AdoCbl [mitochondrial matrix]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Homo sapiens)
Cobalamin (Cbl) metabolism (Homo sapiens)
MMAA:MUT binds AdoCbl (Homo sapiens)
AdoCbl [mitochondrial matrix]
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Homo sapiens)
AdoCbl [mitochondrial matrix]
MMAB adenosylates cob(I)alamin (Homo sapiens)
AdoCbl [mitochondrial matrix]
Metabolism (Mus musculus)
Metabolism of lipids (Mus musculus)
Fatty acid metabolism (Mus musculus)
Mitochondrial Fatty Acid Beta-Oxidation (Mus musculus)
Propionyl-CoA catabolism (Mus musculus)
MUT isomerises L-MM-CoA to SUCC-CoA (Mus musculus)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Mus musculus)
AdoCbl [mitochondrial matrix]
2xMUT:AdoCbl [mitochondrial matrix] (Mus musculus)
AdoCbl [mitochondrial matrix]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Mus musculus)
Cobalamin (Cbl) metabolism (Mus musculus)
MMAA:MUT binds AdoCbl (Mus musculus)
AdoCbl [mitochondrial matrix]
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Mus musculus)
AdoCbl [mitochondrial matrix]
MMAB adenosylates cob(I)alamin (Mus musculus)
AdoCbl [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Mitochondrial Fatty Acid Beta-Oxidation (Rattus norvegicus)
Propionyl-CoA catabolism (Rattus norvegicus)
MUT isomerises L-MM-CoA to SUCC-CoA (Rattus norvegicus)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Rattus norvegicus)
AdoCbl [mitochondrial matrix]
2xMUT:AdoCbl [mitochondrial matrix] (Rattus norvegicus)
AdoCbl [mitochondrial matrix]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Rattus norvegicus)
Cobalamin (Cbl) metabolism (Rattus norvegicus)
MMAA:MUT binds AdoCbl (Rattus norvegicus)
AdoCbl [mitochondrial matrix]
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Rattus norvegicus)
AdoCbl [mitochondrial matrix]
MMAB adenosylates cob(I)alamin (Rattus norvegicus)
AdoCbl [mitochondrial matrix]
Metabolism (Sus scrofa)
Metabolism of lipids (Sus scrofa)
Fatty acid metabolism (Sus scrofa)
Mitochondrial Fatty Acid Beta-Oxidation (Sus scrofa)
Propionyl-CoA catabolism (Sus scrofa)
MUT isomerises L-MM-CoA to SUCC-CoA (Sus scrofa)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Sus scrofa)
AdoCbl [mitochondrial matrix]
2xMUT:AdoCbl [mitochondrial matrix] (Sus scrofa)
AdoCbl [mitochondrial matrix]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Sus scrofa)
Cobalamin (Cbl) metabolism (Sus scrofa)
MMAA:MUT binds AdoCbl (Sus scrofa)
AdoCbl [mitochondrial matrix]
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Sus scrofa)
AdoCbl [mitochondrial matrix]
MMAB adenosylates cob(I)alamin (Sus scrofa)
AdoCbl [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of water-soluble vitamins and cofactors (Xenopus tropicalis)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Xenopus tropicalis)
Cobalamin (Cbl) metabolism (Xenopus tropicalis)
MMAB adenosylates cob(I)alamin (Xenopus tropicalis)
AdoCbl [mitochondrial matrix]
External Reference Information
External Reference
cobamamide [ChEBI:18408]
Participates
as a component of
mutant MUT:AdoCbl [mitochondrial matrix] (Homo sapiens)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Danio rerio)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Mus musculus)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Bos taurus)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Sus scrofa)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Canis familiaris)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Rattus norvegicus)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Caenorhabditis elegans)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Gallus gallus)
2xMMAA:2xMUT:AdoCbl [mitochondrial matrix] (Homo sapiens)
2xMUT:AdoCbl [mitochondrial matrix] (Canis familiaris)
2xMUT:AdoCbl [mitochondrial matrix] (Caenorhabditis elegans)
2xMUT:AdoCbl [mitochondrial matrix] (Mus musculus)
2xMUT:AdoCbl [mitochondrial matrix] (Gallus gallus)
2xMUT:AdoCbl [mitochondrial matrix] (Sus scrofa)
2xMUT:AdoCbl [mitochondrial matrix] (Rattus norvegicus)
2xMUT:AdoCbl [mitochondrial matrix] (Bos taurus)
2xMUT:AdoCbl [mitochondrial matrix] (Danio rerio)
2xMUT:AdoCbl [mitochondrial matrix] (Homo sapiens)
as an input of
Defective MMAA does not protect MUT (Homo sapiens)
MMAA:MUT binds AdoCbl (Caenorhabditis elegans)
MMAA:MUT binds AdoCbl (Gallus gallus)
MMAA:MUT binds AdoCbl (Danio rerio)
MMAA:MUT binds AdoCbl (Sus scrofa)
MMAA:MUT binds AdoCbl (Bos taurus)
MMAA:MUT binds AdoCbl (Canis familiaris)
MMAA:MUT binds AdoCbl (Rattus norvegicus)
MMAA:MUT binds AdoCbl (Mus musculus)
MMAA:MUT binds AdoCbl (Homo sapiens)
as an output of
MMAB adenosylates cob(I)alamin (Dictyostelium discoideum)
MMAB adenosylates cob(I)alamin (Caenorhabditis elegans)
MMAB adenosylates cob(I)alamin (Gallus gallus)
MMAB adenosylates cob(I)alamin (Xenopus tropicalis)
MMAB adenosylates cob(I)alamin (Sus scrofa)
MMAB adenosylates cob(I)alamin (Bos taurus)
MMAB adenosylates cob(I)alamin (Canis familiaris)
MMAB adenosylates cob(I)alamin (Rattus norvegicus)
MMAB adenosylates cob(I)alamin (Mus musculus)
MMAB adenosylates cob(I)alamin (Homo sapiens)
Cross References
COMPOUND
C00194
PubChem Substance
8143774
HMDB Metabolite
HMDB0002086
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