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Fru 1-P [cytosol]
Stable Identifier
R-ALL-31221
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
D-Fructose 1-phosphate, keto-D-fructose 1-phosphate
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of carbohydrates (Bos taurus)
Fructose metabolism (Bos taurus)
Fructose catabolism (Bos taurus)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Bos taurus)
Fru 1-P [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Bos taurus)
Fru 1-P [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of carbohydrates (Caenorhabditis elegans)
Fructose metabolism (Caenorhabditis elegans)
Fructose catabolism (Caenorhabditis elegans)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Caenorhabditis elegans)
Fru 1-P [cytosol]
Metabolism (Canis familiaris)
Metabolism of carbohydrates (Canis familiaris)
Fructose metabolism (Canis familiaris)
Fructose catabolism (Canis familiaris)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Canis familiaris)
Fru 1-P [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Canis familiaris)
Fru 1-P [cytosol]
Metabolism (Danio rerio)
Metabolism of carbohydrates (Danio rerio)
Fructose metabolism (Danio rerio)
Fructose catabolism (Danio rerio)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Danio rerio)
Fru 1-P [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Danio rerio)
Fru 1-P [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of carbohydrates (Dictyostelium discoideum)
Fructose metabolism (Dictyostelium discoideum)
Fructose catabolism (Dictyostelium discoideum)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Dictyostelium discoideum)
Fru 1-P [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Dictyostelium discoideum)
Fru 1-P [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of carbohydrates (Drosophila melanogaster)
Fructose metabolism (Drosophila melanogaster)
Fructose catabolism (Drosophila melanogaster)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Drosophila melanogaster)
Fru 1-P [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Drosophila melanogaster)
Fru 1-P [cytosol]
Metabolism (Gallus gallus)
Metabolism of carbohydrates (Gallus gallus)
Fructose metabolism (Gallus gallus)
Fructose catabolism (Gallus gallus)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Gallus gallus)
Fru 1-P [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Gallus gallus)
Fru 1-P [cytosol]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of carbohydrate metabolism (Homo sapiens)
Hereditary fructose intolerance (Homo sapiens)
Defective ALDOB does not cleave Fru 1-P to GA and DHAP (Homo sapiens)
Fru 1-P [cytosol]
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Fructose metabolism (Homo sapiens)
Fructose catabolism (Homo sapiens)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Homo sapiens)
Fru 1-P [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Homo sapiens)
Fru 1-P [cytosol]
Glucose metabolism (Homo sapiens)
Glycolysis (Homo sapiens)
Regulation of Glucokinase by Glucokinase Regulatory Protein (Homo sapiens)
cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) (Homo sapiens)
Fru 1-P [cytosol]
glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex (Homo sapiens)
Fru 1-P [cytosol]
Metabolism (Mus musculus)
Metabolism of carbohydrates (Mus musculus)
Fructose metabolism (Mus musculus)
Fructose catabolism (Mus musculus)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Mus musculus)
Fru 1-P [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Mus musculus)
Fru 1-P [cytosol]
Glucose metabolism (Mus musculus)
Glycolysis (Mus musculus)
Regulation of Glucokinase by Glucokinase Regulatory Protein (Mus musculus)
cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) (Mus musculus)
Fru 1-P [cytosol]
glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex (Mus musculus)
Fru 1-P [cytosol]
Metabolism (Plasmodium falciparum)
Metabolism of carbohydrates (Plasmodium falciparum)
Fructose metabolism (Plasmodium falciparum)
Fructose catabolism (Plasmodium falciparum)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Plasmodium falciparum)
Fru 1-P [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of carbohydrates (Rattus norvegicus)
Fructose metabolism (Rattus norvegicus)
Fructose catabolism (Rattus norvegicus)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Rattus norvegicus)
Fru 1-P [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Rattus norvegicus)
Fru 1-P [cytosol]
Glucose metabolism (Rattus norvegicus)
Glycolysis (Rattus norvegicus)
Regulation of Glucokinase by Glucokinase Regulatory Protein (Rattus norvegicus)
cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) (Rattus norvegicus)
Fru 1-P [cytosol]
glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex (Rattus norvegicus)
Fru 1-P [cytosol]
Metabolism (Sus scrofa)
Metabolism of carbohydrates (Sus scrofa)
Fructose metabolism (Sus scrofa)
Fructose catabolism (Sus scrofa)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Sus scrofa)
Fru 1-P [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Sus scrofa)
Fru 1-P [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of carbohydrates (Xenopus tropicalis)
Fructose metabolism (Xenopus tropicalis)
Fructose catabolism (Xenopus tropicalis)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Xenopus tropicalis)
Fru 1-P [cytosol]
Glucose metabolism (Xenopus tropicalis)
Glycolysis (Xenopus tropicalis)
Regulation of Glucokinase by Glucokinase Regulatory Protein (Xenopus tropicalis)
cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) (Xenopus tropicalis)
Fru 1-P [cytosol]
glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex (Xenopus tropicalis)
Fru 1-P [cytosol]
External Reference Information
External Reference
keto-D-fructose 1-phosphate [ChEBI:18105]
Participates
as an input of
Defective ALDOB does not cleave Fru 1-P to GA and DHAP (Homo sapiens)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Plasmodium falciparum)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Dictyostelium discoideum)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Caenorhabditis elegans)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Drosophila melanogaster)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Gallus gallus)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Xenopus tropicalis)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Danio rerio)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Sus scrofa)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Bos taurus)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Canis familiaris)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Rattus norvegicus)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Mus musculus)
ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Homo sapiens)
as an output of
KHK dimer phosphorylates Fru to Fru 1-P (Dictyostelium discoideum)
KHK dimer phosphorylates Fru to Fru 1-P (Drosophila melanogaster)
KHK dimer phosphorylates Fru to Fru 1-P (Gallus gallus)
KHK dimer phosphorylates Fru to Fru 1-P (Danio rerio)
KHK dimer phosphorylates Fru to Fru 1-P (Sus scrofa)
KHK dimer phosphorylates Fru to Fru 1-P (Bos taurus)
KHK dimer phosphorylates Fru to Fru 1-P (Canis familiaris)
KHK dimer phosphorylates Fru to Fru 1-P (Rattus norvegicus)
KHK dimer phosphorylates Fru to Fru 1-P (Mus musculus)
KHK dimer phosphorylates Fru to Fru 1-P (Homo sapiens)
This entity regulates
Negatively
glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex
(Xenopus tropicalis)
glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex
(Rattus norvegicus)
glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex
(Mus musculus)
glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex
(Homo sapiens)
Positively
cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP)
(Xenopus tropicalis)
cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP)
(Rattus norvegicus)
cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP)
(Mus musculus)
cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP)
(Homo sapiens)
Cross References
COMPOUND
C01094
PubChem Substance
8143888
HMDB Metabolite
HMDB0060467
ZINC
000018140538
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