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amiloride [extracellular region]
Stable Identifier
R-ALL-2672379
Type
ChemicalDrug
Compartment
extracellular region
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Sensory Perception (Bos taurus)
Sensory perception of taste (Bos taurus)
Sensory perception of salty taste (Bos taurus)
SCNN channels transport extracellular Na+ to cytosol (Bos taurus)
amiloride [extracellular region]
Transport of small molecules (Bos taurus)
Ion channel transport (Bos taurus)
Stimuli-sensing channels (Bos taurus)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Bos taurus)
amiloride [extracellular region]
ASIC3 channel blockers bind ASIC3 trimer (Bos taurus)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
ASIC3 trimer:ASIC3 channel blockers [plasma membrane] (Bos taurus)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
SCNN channels transport extracellular Na+ to cytosol (Bos taurus)
amiloride [extracellular region]
Sensory Perception (Caenorhabditis elegans)
Sensory perception of taste (Caenorhabditis elegans)
Sensory perception of salty taste (Caenorhabditis elegans)
SCNN channels transport extracellular Na+ to cytosol (Caenorhabditis elegans)
amiloride [extracellular region]
Transport of small molecules (Caenorhabditis elegans)
Ion channel transport (Caenorhabditis elegans)
Stimuli-sensing channels (Caenorhabditis elegans)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Caenorhabditis elegans)
amiloride [extracellular region]
ASIC3 channel blockers bind ASIC3 trimer (Caenorhabditis elegans)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
ASIC3 trimer:ASIC3 channel blockers [plasma membrane] (Caenorhabditis elegans)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
SCNN channels transport extracellular Na+ to cytosol (Caenorhabditis elegans)
amiloride [extracellular region]
Sensory Perception (Canis familiaris)
Sensory perception of taste (Canis familiaris)
Sensory perception of salty taste (Canis familiaris)
SCNN channels transport extracellular Na+ to cytosol (Canis familiaris)
amiloride [extracellular region]
Transport of small molecules (Canis familiaris)
Ion channel transport (Canis familiaris)
Stimuli-sensing channels (Canis familiaris)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Canis familiaris)
amiloride [extracellular region]
ASIC3 channel blockers bind ASIC3 trimer (Canis familiaris)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
ASIC3 trimer:ASIC3 channel blockers [plasma membrane] (Canis familiaris)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
SCNN channels transport extracellular Na+ to cytosol (Canis familiaris)
amiloride [extracellular region]
Transport of small molecules (Danio rerio)
Ion channel transport (Danio rerio)
Stimuli-sensing channels (Danio rerio)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Danio rerio)
amiloride [extracellular region]
ASIC3 channel blockers bind ASIC3 trimer (Danio rerio)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
ASIC3 trimer:ASIC3 channel blockers [plasma membrane] (Danio rerio)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
Transport of small molecules (Drosophila melanogaster)
Ion channel transport (Drosophila melanogaster)
Stimuli-sensing channels (Drosophila melanogaster)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Drosophila melanogaster)
amiloride [extracellular region]
ASIC3 channel blockers bind ASIC3 trimer (Drosophila melanogaster)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
ASIC3 trimer:ASIC3 channel blockers [plasma membrane] (Drosophila melanogaster)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
Sensory Perception (Gallus gallus)
Sensory perception of taste (Gallus gallus)
Sensory perception of salty taste (Gallus gallus)
SCNN channels transport extracellular Na+ to cytosol (Gallus gallus)
amiloride [extracellular region]
Transport of small molecules (Gallus gallus)
Ion channel transport (Gallus gallus)
Stimuli-sensing channels (Gallus gallus)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Gallus gallus)
amiloride [extracellular region]
ASIC3 channel blockers bind ASIC3 trimer (Gallus gallus)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
ASIC3 trimer:ASIC3 channel blockers [plasma membrane] (Gallus gallus)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
SCNN channels transport extracellular Na+ to cytosol (Gallus gallus)
amiloride [extracellular region]
Sensory Perception (Homo sapiens)
Sensory perception of taste (Homo sapiens)
Sensory perception of salty taste (Homo sapiens)
SCNN channels transport extracellular Na+ to cytosol (Homo sapiens)
amiloride [extracellular region]
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Stimuli-sensing channels (Homo sapiens)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Homo sapiens)
amiloride [extracellular region]
ASIC3 channel blockers bind ASIC3 trimer (Homo sapiens)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
ASIC3 trimer:ASIC3 channel blockers [plasma membrane] (Homo sapiens)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
SCNN channels transport extracellular Na+ to cytosol (Homo sapiens)
amiloride [extracellular region]
Sensory Perception (Mus musculus)
Sensory perception of taste (Mus musculus)
Sensory perception of salty taste (Mus musculus)
SCNN channels transport extracellular Na+ to cytosol (Mus musculus)
amiloride [extracellular region]
Transport of small molecules (Mus musculus)
Ion channel transport (Mus musculus)
Stimuli-sensing channels (Mus musculus)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Mus musculus)
amiloride [extracellular region]
ASIC3 channel blockers bind ASIC3 trimer (Mus musculus)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
ASIC3 trimer:ASIC3 channel blockers [plasma membrane] (Mus musculus)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
SCNN channels transport extracellular Na+ to cytosol (Mus musculus)
amiloride [extracellular region]
Sensory Perception (Rattus norvegicus)
Sensory perception of taste (Rattus norvegicus)
Sensory perception of salty taste (Rattus norvegicus)
SCNN channels transport extracellular Na+ to cytosol (Rattus norvegicus)
amiloride [extracellular region]
Transport of small molecules (Rattus norvegicus)
Ion channel transport (Rattus norvegicus)
Stimuli-sensing channels (Rattus norvegicus)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Rattus norvegicus)
amiloride [extracellular region]
ASIC3 channel blockers bind ASIC3 trimer (Rattus norvegicus)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
ASIC3 trimer:ASIC3 channel blockers [plasma membrane] (Rattus norvegicus)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
SCNN channels transport extracellular Na+ to cytosol (Rattus norvegicus)
amiloride [extracellular region]
Sensory Perception (Sus scrofa)
Sensory perception of taste (Sus scrofa)
Sensory perception of salty taste (Sus scrofa)
SCNN channels transport extracellular Na+ to cytosol (Sus scrofa)
amiloride [extracellular region]
Transport of small molecules (Sus scrofa)
Ion channel transport (Sus scrofa)
Stimuli-sensing channels (Sus scrofa)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Sus scrofa)
amiloride [extracellular region]
ASIC3 channel blockers bind ASIC3 trimer (Sus scrofa)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
ASIC3 trimer:ASIC3 channel blockers [plasma membrane] (Sus scrofa)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
SCNN channels transport extracellular Na+ to cytosol (Sus scrofa)
amiloride [extracellular region]
Sensory Perception (Xenopus tropicalis)
Sensory perception of taste (Xenopus tropicalis)
Sensory perception of salty taste (Xenopus tropicalis)
SCNN channels transport extracellular Na+ to cytosol (Xenopus tropicalis)
amiloride [extracellular region]
Transport of small molecules (Xenopus tropicalis)
Ion channel transport (Xenopus tropicalis)
Stimuli-sensing channels (Xenopus tropicalis)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Xenopus tropicalis)
amiloride [extracellular region]
ASIC3 channel blockers bind ASIC3 trimer (Xenopus tropicalis)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
ASIC3 trimer:ASIC3 channel blockers [plasma membrane] (Xenopus tropicalis)
ASIC3 channel blockers [extracellular region]
amiloride [extracellular region]
SCNN channels transport extracellular Na+ to cytosol (Xenopus tropicalis)
amiloride [extracellular region]
External Reference Information
External Reference
amiloride [Guide to Pharmacology:2421]
Participates
as a member of
ASIC3 channel blockers [extracellular region]
This entity regulates
Negatively
SCNN channels transport extracellular Na+ to cytosol
(Caenorhabditis elegans)
SCNN channels transport extracellular Na+ to cytosol
(Gallus gallus)
SCNN channels transport extracellular Na+ to cytosol
(Xenopus tropicalis)
SCNN channels transport extracellular Na+ to cytosol
(Sus scrofa)
SCNN channels transport extracellular Na+ to cytosol
(Bos taurus)
SCNN channels transport extracellular Na+ to cytosol
(Canis familiaris)
SCNN channels transport extracellular Na+ to cytosol
(Rattus norvegicus)
SCNN channels transport extracellular Na+ to cytosol
(Mus musculus)
SCNN channels transport extracellular Na+ to cytosol
(Homo sapiens)
ASIC trimers:H+ transport extracellular Na+ to cytosol
(Caenorhabditis elegans)
ASIC trimers:H+ transport extracellular Na+ to cytosol
(Drosophila melanogaster)
ASIC trimers:H+ transport extracellular Na+ to cytosol
(Gallus gallus)
ASIC trimers:H+ transport extracellular Na+ to cytosol
(Xenopus tropicalis)
ASIC trimers:H+ transport extracellular Na+ to cytosol
(Danio rerio)
ASIC trimers:H+ transport extracellular Na+ to cytosol
(Sus scrofa)
ASIC trimers:H+ transport extracellular Na+ to cytosol
(Bos taurus)
ASIC trimers:H+ transport extracellular Na+ to cytosol
(Canis familiaris)
ASIC trimers:H+ transport extracellular Na+ to cytosol
(Rattus norvegicus)
ASIC trimers:H+ transport extracellular Na+ to cytosol
(Mus musculus)
ASIC trimers:H+ transport extracellular Na+ to cytosol
(Homo sapiens)
Disease
Name
Identifier
Synonyms
hypertension
DOID:10763
High blood pressure (& [essential hypertension]), HTN, hypertensive disease, hyperpiesia, vascular hypertensive disorder
congestive heart failure
DOID:6000
CHF, Cardiac Failure Congestive, Weak heart, Congestive heart disease
Cross References
Pharos - Ligands
1DKCKQ65KQGJ
PharmacoDB
PDBC00677
PubChem Compound
135649936
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