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GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
Stable Identifier
R-ALL-2104995
Type
Chemical Compound [SimpleEntity]
Compartment
lysosomal lumen
Synonyms
beta-D-GlcpNAc6S-(1->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc6S-(1->3)-D-Galp
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of carbohydrates (Bos taurus)
Glycosaminoglycan metabolism (Bos taurus)
Keratan sulfate/keratin metabolism (Bos taurus)
Keratan sulfate degradation (Bos taurus)
GLB1 hydrolyses a glycosaminoglycan (Bos taurus)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Bos taurus)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
Metabolism (Caenorhabditis elegans)
Metabolism of carbohydrates (Caenorhabditis elegans)
Glycosaminoglycan metabolism (Caenorhabditis elegans)
Keratan sulfate/keratin metabolism (Caenorhabditis elegans)
Keratan sulfate degradation (Caenorhabditis elegans)
GLB1 hydrolyses a glycosaminoglycan (Caenorhabditis elegans)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
Metabolism (Canis familiaris)
Metabolism of carbohydrates (Canis familiaris)
Glycosaminoglycan metabolism (Canis familiaris)
Keratan sulfate/keratin metabolism (Canis familiaris)
Keratan sulfate degradation (Canis familiaris)
GLB1 hydrolyses a glycosaminoglycan (Canis familiaris)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Canis familiaris)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
Metabolism (Danio rerio)
Metabolism of carbohydrates (Danio rerio)
Glycosaminoglycan metabolism (Danio rerio)
Keratan sulfate/keratin metabolism (Danio rerio)
Keratan sulfate degradation (Danio rerio)
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Danio rerio)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
Metabolism (Dictyostelium discoideum)
Metabolism of carbohydrates (Dictyostelium discoideum)
Glycosaminoglycan metabolism (Dictyostelium discoideum)
Keratan sulfate/keratin metabolism (Dictyostelium discoideum)
Keratan sulfate degradation (Dictyostelium discoideum)
GLB1 hydrolyses a glycosaminoglycan (Dictyostelium discoideum)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
Metabolism (Drosophila melanogaster)
Metabolism of carbohydrates (Drosophila melanogaster)
Glycosaminoglycan metabolism (Drosophila melanogaster)
Keratan sulfate/keratin metabolism (Drosophila melanogaster)
Keratan sulfate degradation (Drosophila melanogaster)
GLB1 hydrolyses a glycosaminoglycan (Drosophila melanogaster)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Drosophila melanogaster)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
Metabolism (Gallus gallus)
Metabolism of carbohydrates (Gallus gallus)
Glycosaminoglycan metabolism (Gallus gallus)
Keratan sulfate/keratin metabolism (Gallus gallus)
Keratan sulfate degradation (Gallus gallus)
GLB1 hydrolyses a glycosaminoglycan (Gallus gallus)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Gallus gallus)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of carbohydrate metabolism (Homo sapiens)
Mucopolysaccharidoses (Homo sapiens)
MPS IIID - Sanfilippo syndrome D (Homo sapiens)
Defective GNS does not hydrolyse 6-sulfate from GlcNAc6S (Homo sapiens)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Keratan sulfate/keratin metabolism (Homo sapiens)
Keratan sulfate degradation (Homo sapiens)
GLB1 hydrolyses a glycosaminoglycan (Homo sapiens)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Homo sapiens)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
Metabolism (Mus musculus)
Metabolism of carbohydrates (Mus musculus)
Glycosaminoglycan metabolism (Mus musculus)
Keratan sulfate/keratin metabolism (Mus musculus)
Keratan sulfate degradation (Mus musculus)
GLB1 hydrolyses a glycosaminoglycan (Mus musculus)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Mus musculus)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
Metabolism (Rattus norvegicus)
Metabolism of carbohydrates (Rattus norvegicus)
Glycosaminoglycan metabolism (Rattus norvegicus)
Keratan sulfate/keratin metabolism (Rattus norvegicus)
Keratan sulfate degradation (Rattus norvegicus)
GLB1 hydrolyses a glycosaminoglycan (Rattus norvegicus)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Rattus norvegicus)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
Metabolism (Sus scrofa)
Metabolism of carbohydrates (Sus scrofa)
Glycosaminoglycan metabolism (Sus scrofa)
Keratan sulfate/keratin metabolism (Sus scrofa)
Keratan sulfate degradation (Sus scrofa)
GLB1 hydrolyses a glycosaminoglycan (Sus scrofa)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Sus scrofa)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
Metabolism (Xenopus tropicalis)
Metabolism of carbohydrates (Xenopus tropicalis)
Glycosaminoglycan metabolism (Xenopus tropicalis)
Keratan sulfate/keratin metabolism (Xenopus tropicalis)
Keratan sulfate degradation (Xenopus tropicalis)
GLB1 hydrolyses a glycosaminoglycan (Xenopus tropicalis)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Xenopus tropicalis)
GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]
External Reference Information
External Reference
beta-D-GlcpNAc6S-(1->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc6S-(1->3)-D-Galp [ChEBI:63851]
Participates
as an input of
Defective GNS does not hydrolyse 6-sulfate from GlcNAc6S (Homo sapiens)
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Drosophila melanogaster)
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Xenopus tropicalis)
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Danio rerio)
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Sus scrofa)
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Bos taurus)
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Canis familiaris)
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Rattus norvegicus)
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Mus musculus)
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Homo sapiens)
N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Gallus gallus)
as an output of
GLB1 hydrolyses a glycosaminoglycan (Dictyostelium discoideum)
GLB1 hydrolyses a glycosaminoglycan (Caenorhabditis elegans)
GLB1 hydrolyses a glycosaminoglycan (Drosophila melanogaster)
GLB1 hydrolyses a glycosaminoglycan (Xenopus tropicalis)
GLB1 hydrolyses a glycosaminoglycan (Sus scrofa)
GLB1 hydrolyses a glycosaminoglycan (Bos taurus)
GLB1 hydrolyses a glycosaminoglycan (Canis familiaris)
GLB1 hydrolyses a glycosaminoglycan (Rattus norvegicus)
GLB1 hydrolyses a glycosaminoglycan (Mus musculus)
GLB1 hydrolyses a glycosaminoglycan (Homo sapiens)
GLB1 hydrolyses a glycosaminoglycan (Gallus gallus)
Cross References
KEGG Glycan
G06780
ZINC
000096085297
,
000096085298
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