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What is Reactome ?
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Digital Preservation
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ADR [cytosol]
Stable Identifier
R-ALL-209794
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
(R)-adrenaline(1+), Adrenaline, (R)-adrenaline, Epinephrine
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Metabolism of amine-derived hormones (Bos taurus)
Catecholamine biosynthesis (Bos taurus)
Noradrenaline is converted to adrenaline (Bos taurus)
ADR [cytosol]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of bile salts and organic acids, metal ions and amine compounds (Bos taurus)
Na+/Cl- dependent neurotransmitter transporters (Bos taurus)
VMAT1/2 can mediate the transport of biogenic amines (Bos taurus)
Biogenic amines transported by VMAT1/2 [cytosol]
ADR [cytosol]
Organic cation/anion/zwitterion transport (Bos taurus)
Organic cation transport (Bos taurus)
OCT1 transports organic cations into hepatic cells (Bos taurus)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT1 transports organic cations out of hepatic cells (Bos taurus)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Bos taurus)
OCT2 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Bos taurus)
OCT2 substrates [cytosol]
ADR [cytosol]
Transport of vitamins, nucleosides, and related molecules (Bos taurus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Bos taurus)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Bos taurus)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Bos taurus)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Metabolism of amine-derived hormones (Caenorhabditis elegans)
Catecholamine biosynthesis (Caenorhabditis elegans)
Noradrenaline is converted to adrenaline (Caenorhabditis elegans)
ADR [cytosol]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of bile salts and organic acids, metal ions and amine compounds (Caenorhabditis elegans)
Na+/Cl- dependent neurotransmitter transporters (Caenorhabditis elegans)
VMAT1/2 can mediate the transport of biogenic amines (Caenorhabditis elegans)
Biogenic amines transported by VMAT1/2 [cytosol]
ADR [cytosol]
Organic cation/anion/zwitterion transport (Caenorhabditis elegans)
Organic cation transport (Caenorhabditis elegans)
OCT1 transports organic cations into hepatic cells (Caenorhabditis elegans)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT1 transports organic cations out of hepatic cells (Caenorhabditis elegans)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Caenorhabditis elegans)
OCT2 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Caenorhabditis elegans)
OCT2 substrates [cytosol]
ADR [cytosol]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Metabolism of amine-derived hormones (Canis familiaris)
Catecholamine biosynthesis (Canis familiaris)
Noradrenaline is converted to adrenaline (Canis familiaris)
ADR [cytosol]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of bile salts and organic acids, metal ions and amine compounds (Canis familiaris)
Na+/Cl- dependent neurotransmitter transporters (Canis familiaris)
VMAT1/2 can mediate the transport of biogenic amines (Canis familiaris)
Biogenic amines transported by VMAT1/2 [cytosol]
ADR [cytosol]
Organic cation/anion/zwitterion transport (Canis familiaris)
Organic cation transport (Canis familiaris)
OCT1 transports organic cations into hepatic cells (Canis familiaris)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT1 transports organic cations out of hepatic cells (Canis familiaris)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Canis familiaris)
OCT2 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Canis familiaris)
OCT2 substrates [cytosol]
ADR [cytosol]
Transport of vitamins, nucleosides, and related molecules (Canis familiaris)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Canis familiaris)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Canis familiaris)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Canis familiaris)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of bile salts and organic acids, metal ions and amine compounds (Danio rerio)
Organic cation/anion/zwitterion transport (Danio rerio)
Organic cation transport (Danio rerio)
OCT1 transports organic cations into hepatic cells (Danio rerio)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT1 transports organic cations out of hepatic cells (Danio rerio)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Danio rerio)
OCT2 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Danio rerio)
OCT2 substrates [cytosol]
ADR [cytosol]
Transport of vitamins, nucleosides, and related molecules (Danio rerio)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Danio rerio)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Danio rerio)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Danio rerio)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Transport of small molecules (Dictyostelium discoideum)
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Transport of vitamins, nucleosides, and related molecules (Dictyostelium discoideum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Dictyostelium discoideum)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Dictyostelium discoideum)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Dictyostelium discoideum)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of bile salts and organic acids, metal ions and amine compounds (Drosophila melanogaster)
Na+/Cl- dependent neurotransmitter transporters (Drosophila melanogaster)
VMAT1/2 can mediate the transport of biogenic amines (Drosophila melanogaster)
Biogenic amines transported by VMAT1/2 [cytosol]
ADR [cytosol]
Organic cation/anion/zwitterion transport (Drosophila melanogaster)
Organic cation transport (Drosophila melanogaster)
OCT1 transports organic cations into hepatic cells (Drosophila melanogaster)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT1 transports organic cations out of hepatic cells (Drosophila melanogaster)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Drosophila melanogaster)
OCT2 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Drosophila melanogaster)
OCT2 substrates [cytosol]
ADR [cytosol]
Transport of vitamins, nucleosides, and related molecules (Drosophila melanogaster)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Drosophila melanogaster)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Drosophila melanogaster)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Drosophila melanogaster)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Metabolism of amine-derived hormones (Gallus gallus)
Catecholamine biosynthesis (Gallus gallus)
Noradrenaline is converted to adrenaline (Gallus gallus)
ADR [cytosol]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of bile salts and organic acids, metal ions and amine compounds (Gallus gallus)
Na+/Cl- dependent neurotransmitter transporters (Gallus gallus)
VMAT1/2 can mediate the transport of biogenic amines (Gallus gallus)
Biogenic amines transported by VMAT1/2 [cytosol]
ADR [cytosol]
Organic cation/anion/zwitterion transport (Gallus gallus)
Organic cation transport (Gallus gallus)
OCT1 transports organic cations into hepatic cells (Gallus gallus)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT1 transports organic cations out of hepatic cells (Gallus gallus)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Gallus gallus)
OCT2 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Gallus gallus)
OCT2 substrates [cytosol]
ADR [cytosol]
Transport of vitamins, nucleosides, and related molecules (Gallus gallus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Gallus gallus)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Gallus gallus)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Gallus gallus)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Metabolism of amine-derived hormones (Homo sapiens)
Catecholamine biosynthesis (Homo sapiens)
Noradrenaline is converted to adrenaline (Homo sapiens)
ADR [cytosol]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Na+/Cl- dependent neurotransmitter transporters (Homo sapiens)
VMAT1/2 can mediate the transport of biogenic amines (Homo sapiens)
Biogenic amines transported by VMAT1/2 [cytosol]
ADR [cytosol]
Organic cation/anion/zwitterion transport (Homo sapiens)
Organic cation transport (Homo sapiens)
OCT1 transports organic cations into hepatic cells (Homo sapiens)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT1 transports organic cations out of hepatic cells (Homo sapiens)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Homo sapiens)
OCT2 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Homo sapiens)
OCT2 substrates [cytosol]
ADR [cytosol]
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Homo sapiens)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Homo sapiens)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Homo sapiens)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Metabolism of amine-derived hormones (Mus musculus)
Catecholamine biosynthesis (Mus musculus)
Noradrenaline is converted to adrenaline (Mus musculus)
ADR [cytosol]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of bile salts and organic acids, metal ions and amine compounds (Mus musculus)
Na+/Cl- dependent neurotransmitter transporters (Mus musculus)
VMAT1/2 can mediate the transport of biogenic amines (Mus musculus)
Biogenic amines transported by VMAT1/2 [cytosol]
ADR [cytosol]
Organic cation/anion/zwitterion transport (Mus musculus)
Organic cation transport (Mus musculus)
OCT1 transports organic cations into hepatic cells (Mus musculus)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT1 transports organic cations out of hepatic cells (Mus musculus)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Mus musculus)
OCT2 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Mus musculus)
OCT2 substrates [cytosol]
ADR [cytosol]
Transport of vitamins, nucleosides, and related molecules (Mus musculus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Mus musculus)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Mus musculus)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Mus musculus)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Transport of small molecules (Plasmodium falciparum)
SLC-mediated transmembrane transport (Plasmodium falciparum)
Transport of vitamins, nucleosides, and related molecules (Plasmodium falciparum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Plasmodium falciparum)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Plasmodium falciparum)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Plasmodium falciparum)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Metabolism of amine-derived hormones (Rattus norvegicus)
Catecholamine biosynthesis (Rattus norvegicus)
Noradrenaline is converted to adrenaline (Rattus norvegicus)
ADR [cytosol]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of bile salts and organic acids, metal ions and amine compounds (Rattus norvegicus)
Na+/Cl- dependent neurotransmitter transporters (Rattus norvegicus)
VMAT1/2 can mediate the transport of biogenic amines (Rattus norvegicus)
Biogenic amines transported by VMAT1/2 [cytosol]
ADR [cytosol]
Organic cation/anion/zwitterion transport (Rattus norvegicus)
Organic cation transport (Rattus norvegicus)
OCT1 transports organic cations into hepatic cells (Rattus norvegicus)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT1 transports organic cations out of hepatic cells (Rattus norvegicus)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Rattus norvegicus)
OCT2 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Rattus norvegicus)
OCT2 substrates [cytosol]
ADR [cytosol]
Transport of vitamins, nucleosides, and related molecules (Rattus norvegicus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Rattus norvegicus)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Rattus norvegicus)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Rattus norvegicus)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Transport of small molecules (Schizosaccharomyces pombe)
SLC-mediated transmembrane transport (Schizosaccharomyces pombe)
Transport of bile salts and organic acids, metal ions and amine compounds (Schizosaccharomyces pombe)
Na+/Cl- dependent neurotransmitter transporters (Schizosaccharomyces pombe)
VMAT1/2 can mediate the transport of biogenic amines (Schizosaccharomyces pombe)
Biogenic amines transported by VMAT1/2 [cytosol]
ADR [cytosol]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Metabolism of amine-derived hormones (Sus scrofa)
Catecholamine biosynthesis (Sus scrofa)
Noradrenaline is converted to adrenaline (Sus scrofa)
ADR [cytosol]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of bile salts and organic acids, metal ions and amine compounds (Sus scrofa)
Na+/Cl- dependent neurotransmitter transporters (Sus scrofa)
VMAT1/2 can mediate the transport of biogenic amines (Sus scrofa)
Biogenic amines transported by VMAT1/2 [cytosol]
ADR [cytosol]
Organic cation/anion/zwitterion transport (Sus scrofa)
Organic cation transport (Sus scrofa)
OCT1 transports organic cations into hepatic cells (Sus scrofa)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT1 transports organic cations out of hepatic cells (Sus scrofa)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Sus scrofa)
OCT2 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Sus scrofa)
OCT2 substrates [cytosol]
ADR [cytosol]
Transport of vitamins, nucleosides, and related molecules (Sus scrofa)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Sus scrofa)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Sus scrofa)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Sus scrofa)
ligands of SLC29A4 [cytosol]
ADR [cytosol]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of bile salts and organic acids, metal ions and amine compounds (Xenopus tropicalis)
Na+/Cl- dependent neurotransmitter transporters (Xenopus tropicalis)
VMAT1/2 can mediate the transport of biogenic amines (Xenopus tropicalis)
Biogenic amines transported by VMAT1/2 [cytosol]
ADR [cytosol]
Organic cation/anion/zwitterion transport (Xenopus tropicalis)
Organic cation transport (Xenopus tropicalis)
OCT1 transports organic cations into hepatic cells (Xenopus tropicalis)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT1 transports organic cations out of hepatic cells (Xenopus tropicalis)
OCT1 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Xenopus tropicalis)
OCT2 substrates [cytosol]
ADR [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Xenopus tropicalis)
OCT2 substrates [cytosol]
ADR [cytosol]
External Reference Information
External Reference
(R)-adrenaline(1+) [ChEBI:71406]
Participates
as a member of
ligands of SLC29A4 [cytosol]
OCT2 substrates [cytosol]
OCT1 substrates [cytosol]
Biogenic amines transported by VMAT1/2 [cytosol]
as an output of
Noradrenaline is converted to adrenaline (Caenorhabditis elegans)
Noradrenaline is converted to adrenaline (Gallus gallus)
Noradrenaline is converted to adrenaline (Sus scrofa)
Noradrenaline is converted to adrenaline (Bos taurus)
Noradrenaline is converted to adrenaline (Canis familiaris)
Noradrenaline is converted to adrenaline (Rattus norvegicus)
Noradrenaline is converted to adrenaline (Homo sapiens)
Noradrenaline is converted to adrenaline (Mus musculus)
Other forms of this molecule
ADR [clathrin-coated endocytic vesicle membrane]
ADR [clathrin-sculpted monoamine transport vesicle lumen]
ADR [extracellular region]
Cross References
COMPOUND
C00788
ZINC
000000039089
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