masitinib [cytosol]

Stable Identifier
R-ALL-2077524
Type
ChemicalDrug
Compartment
cytosol
Synonyms
AB1010
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General

Masitinib is a multi-kinase inhibitor that targets mutant and wild-type FGFR3, PDGFR and c-KIT (Dubreuil, 2009). It is currently in Phase II clinical trials for multiple myeloma (NCT00866138).

Literature References
PubMed ID Title Journal Year
19789626 Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT

Gros, L, Hajem, B, Hermine, O, Humbert, M, Lermet, A, Letard, S, Leventhal, PS, Mansfield, CD, Arock, M, Voisset, E, Sippl, W, Auclair, C, Moussy, A, Borge, L, Castéran, N, Ciufolini, M, Dubreuil, P

PLoS One 2009
External Reference Information
External Reference
masitinib [Guide to Pharmacology:5656]
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Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
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