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PI(4,5)P2 [endoplasmic reticulum membrane]
Stable Identifier
R-ALL-2023856
Type
Chemical Compound [SimpleEntity]
Compartment
endoplasmic reticulum membrane
Synonyms
PIP2, 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate, Phosphatidylinositol-4,5-bisphosphate, 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate
Locations in the PathwayBrowser for interactor UniProt:P21333%20FLNA
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Inositol phosphate metabolism (Bos taurus)
Synthesis of IP3 and IP4 in the cytosol (Bos taurus)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Bos taurus)
PI(4,5)P2 [endoplasmic reticulum membrane]
Metabolism (Caenorhabditis elegans)
Inositol phosphate metabolism (Caenorhabditis elegans)
Synthesis of IP3 and IP4 in the cytosol (Caenorhabditis elegans)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Caenorhabditis elegans)
PI(4,5)P2 [endoplasmic reticulum membrane]
Metabolism (Canis familiaris)
Inositol phosphate metabolism (Canis familiaris)
Synthesis of IP3 and IP4 in the cytosol (Canis familiaris)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Canis familiaris)
PI(4,5)P2 [endoplasmic reticulum membrane]
Metabolism (Dictyostelium discoideum)
Inositol phosphate metabolism (Dictyostelium discoideum)
Synthesis of IP3 and IP4 in the cytosol (Dictyostelium discoideum)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Dictyostelium discoideum)
PI(4,5)P2 [endoplasmic reticulum membrane]
Metabolism (Drosophila melanogaster)
Inositol phosphate metabolism (Drosophila melanogaster)
Synthesis of IP3 and IP4 in the cytosol (Drosophila melanogaster)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Drosophila melanogaster)
PI(4,5)P2 [endoplasmic reticulum membrane]
Metabolism (Gallus gallus)
Inositol phosphate metabolism (Gallus gallus)
Synthesis of IP3 and IP4 in the cytosol (Gallus gallus)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Gallus gallus)
PI(4,5)P2 [endoplasmic reticulum membrane]
Metabolism (Homo sapiens)
Inositol phosphate metabolism (Homo sapiens)
Synthesis of IP3 and IP4 in the cytosol (Homo sapiens)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Homo sapiens)
PI(4,5)P2 [endoplasmic reticulum membrane]
Metabolism (Mus musculus)
Inositol phosphate metabolism (Mus musculus)
Synthesis of IP3 and IP4 in the cytosol (Mus musculus)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Mus musculus)
PI(4,5)P2 [endoplasmic reticulum membrane]
Metabolism (Plasmodium falciparum)
Inositol phosphate metabolism (Plasmodium falciparum)
Synthesis of IP3 and IP4 in the cytosol (Plasmodium falciparum)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Plasmodium falciparum)
PI(4,5)P2 [endoplasmic reticulum membrane]
Metabolism (Rattus norvegicus)
Inositol phosphate metabolism (Rattus norvegicus)
Synthesis of IP3 and IP4 in the cytosol (Rattus norvegicus)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Rattus norvegicus)
PI(4,5)P2 [endoplasmic reticulum membrane]
Metabolism (Saccharomyces cerevisiae)
Inositol phosphate metabolism (Saccharomyces cerevisiae)
Synthesis of IP3 and IP4 in the cytosol (Saccharomyces cerevisiae)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Saccharomyces cerevisiae)
PI(4,5)P2 [endoplasmic reticulum membrane]
Metabolism (Schizosaccharomyces pombe)
Inositol phosphate metabolism (Schizosaccharomyces pombe)
Synthesis of IP3 and IP4 in the cytosol (Schizosaccharomyces pombe)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Schizosaccharomyces pombe)
PI(4,5)P2 [endoplasmic reticulum membrane]
Metabolism (Sus scrofa)
Inositol phosphate metabolism (Sus scrofa)
Synthesis of IP3 and IP4 in the cytosol (Sus scrofa)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Sus scrofa)
PI(4,5)P2 [endoplasmic reticulum membrane]
Metabolism (Xenopus tropicalis)
Inositol phosphate metabolism (Xenopus tropicalis)
Synthesis of IP3 and IP4 in the cytosol (Xenopus tropicalis)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Xenopus tropicalis)
PI(4,5)P2 [endoplasmic reticulum membrane]
External Reference Information
External Reference
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate(5-) [ChEBI:58456]
Participates
as an input of
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Plasmodium falciparum)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Saccharomyces cerevisiae)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Schizosaccharomyces pombe)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Dictyostelium discoideum)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Caenorhabditis elegans)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Drosophila melanogaster)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Gallus gallus)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Xenopus tropicalis)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Sus scrofa)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Bos taurus)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Canis familiaris)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Rattus norvegicus)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Mus musculus)
PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Homo sapiens)
Other forms of this molecule
PI(4,5)P2 [early endosome membrane]
PI(4,5)P2 [cytoplasmic vesicle membrane]
PI(4,5)P2 [nucleoplasm]
PI(4,5)P2 [Golgi membrane]
PI(4,5)P2 [plasma membrane]
Cross References
COMPOUND
C04637
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