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About
What is Reactome ?
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Digital Preservation
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PI(3,4)P2 [plasma membrane]
Stable Identifier
R-ALL-202247
Type
Chemical Compound [SimpleEntity]
Compartment
plasma membrane
Synonyms
1-phosphatidyl-1D-myo-inositol 3,4-bisphosphates, 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
TCR signaling (Bos taurus)
Downstream TCR signaling (Bos taurus)
Activation of IKK complex (Bos taurus)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Bos taurus)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Bos taurus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Bos taurus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Bos taurus)
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Activation of TAK1-TAB2 complex (Bos taurus)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Bos taurus)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Bos taurus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Bos taurus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Bos taurus)
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Bos taurus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Bos taurus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Bos taurus)
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Hydrolysis of PIP3 to PI(3,4)P2 (Bos taurus)
PI(3,4)P2 [plasma membrane]
Interaction and oligomerization of MALT1 to Bcl10 (Bos taurus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Bos taurus)
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Bos taurus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Bos taurus)
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Interaction of Bcl10 to CARMA1 (Bos taurus)
Bcl10 bound to CARMA1 [plasma membrane] (Bos taurus)
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of Bcl10 (Bos taurus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Bos taurus)
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Bos taurus)
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of CARMA1 (Bos taurus)
Activated CARMA1 [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of Bcl10 (Bos taurus)
Bcl10 bound to CARMA1 [plasma membrane] (Bos taurus)
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Bos taurus)
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of CARMA1 (Bos taurus)
Activated CARMA1 [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 bound to PDK1 [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of PKC theta (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of CARMA1 to Plasma membrane (Bos taurus)
CARMA1 bound to PDK1 [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of PDK1 to Plasma membrane (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of TRAF6 to CBM complex (Bos taurus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Bos taurus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Bos taurus)
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
TRAF6 trimer bound to CBM complex [plasma membrane] (Bos taurus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Bos taurus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Bos taurus)
CARMA1 trimer [plasma membrane] (Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Bos taurus)
Fc epsilon receptor (FCERI) signaling (Bos taurus)
Role of LAT2/NTAL/LAB on calcium mobilization (Bos taurus)
Translocation of PDK1 to Plasma membrane (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Bos taurus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Fcgamma receptor (FCGR) dependent phagocytosis (Bos taurus)
Regulation of actin dynamics for phagocytic cup formation (Bos taurus)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Bos taurus)
PI(3,4)P2 [plasma membrane]
Actin filament bound Myosin-X [plasma membrane] (Bos taurus)
PI(3,4)P2 [plasma membrane]
Metabolism (Bos taurus)
Metabolism of lipids (Bos taurus)
Phospholipid metabolism (Bos taurus)
PI Metabolism (Bos taurus)
Synthesis of PIPs at the plasma membrane (Bos taurus)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Bos taurus)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Bos taurus)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Bos taurus)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Bos taurus)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Bos taurus)
PI(3,4)P2 [plasma membrane]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Bos taurus)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Bos taurus)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Bos taurus)
PI(3,4)P2 [plasma membrane]
Vesicle-mediated transport (Bos taurus)
Membrane Trafficking (Bos taurus)
Clathrin-mediated endocytosis (Bos taurus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Bos taurus)
PI(3,4)P2 [plasma membrane]
F- and N- BAR domain proteins bind the clathrin-coated pit (Bos taurus)
PI(3,4)P2 [plasma membrane]
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
TCR signaling (Caenorhabditis elegans)
Downstream TCR signaling (Caenorhabditis elegans)
Phosphorylation of PKC theta (Caenorhabditis elegans)
PDK1:PIP2,PIP3 [plasma membrane] (Caenorhabditis elegans)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of PDK1 to Plasma membrane (Caenorhabditis elegans)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Caenorhabditis elegans)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Caenorhabditis elegans)
Fc epsilon receptor (FCERI) signaling (Caenorhabditis elegans)
Role of LAT2/NTAL/LAB on calcium mobilization (Caenorhabditis elegans)
Translocation of PDK1 to Plasma membrane (Caenorhabditis elegans)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Caenorhabditis elegans)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Metabolism (Caenorhabditis elegans)
Metabolism of lipids (Caenorhabditis elegans)
Phospholipid metabolism (Caenorhabditis elegans)
PI Metabolism (Caenorhabditis elegans)
Synthesis of PIPs at the plasma membrane (Caenorhabditis elegans)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Caenorhabditis elegans)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Caenorhabditis elegans)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Caenorhabditis elegans)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Caenorhabditis elegans)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Caenorhabditis elegans)
PI(3,4)P2 [plasma membrane]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Caenorhabditis elegans)
PI(3,4)P2 [plasma membrane]
Vesicle-mediated transport (Caenorhabditis elegans)
Membrane Trafficking (Caenorhabditis elegans)
Clathrin-mediated endocytosis (Caenorhabditis elegans)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Caenorhabditis elegans)
PI(3,4)P2 [plasma membrane]
Extracellular matrix organization (Canis familiaris)
Invadopodia formation (Canis familiaris)
SH3PXD2A binds ADAM12,ADAM15,ADAM19 (Canis familiaris)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Canis familiaris)
PI(3,4)P2 [plasma membrane]
SH3PXD2A:PI(3,4)P2:ADAM12,ADAM15,ADAM19 [plasma membrane] (Canis familiaris)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Canis familiaris)
PI(3,4)P2 [plasma membrane]
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
TCR signaling (Canis familiaris)
Downstream TCR signaling (Canis familiaris)
Activation of IKK complex (Canis familiaris)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Canis familiaris)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Canis familiaris)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Canis familiaris)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Activation of TAK1-TAB2 complex (Canis familiaris)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Canis familiaris)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Canis familiaris)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Canis familiaris)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Canis familiaris)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Canis familiaris)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Auto-ubiquitination of TRAF6 (Canis familiaris)
TRAF6 trimer bound to CBM complex [plasma membrane] (Canis familiaris)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Canis familiaris)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Canis familiaris)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Canis familiaris)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Hydrolysis of PIP3 to PI(3,4)P2 (Canis familiaris)
PI(3,4)P2 [plasma membrane]
Interaction and oligomerization of MALT1 to Bcl10 (Canis familiaris)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Canis familiaris)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Interaction of Bcl10 to CARMA1 (Canis familiaris)
Bcl10 bound to CARMA1 [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of Bcl10 (Canis familiaris)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of CARMA1 (Canis familiaris)
Activated CARMA1 [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of Bcl10 (Canis familiaris)
Bcl10 bound to CARMA1 [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of CARMA1 (Canis familiaris)
Activated CARMA1 [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 bound to PDK1 [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of PKC theta (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of CARMA1 to Plasma membrane (Canis familiaris)
CARMA1 bound to PDK1 [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of PDK1 to Plasma membrane (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of TRAF6 to CBM complex (Canis familiaris)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Canis familiaris)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
TRAF6 trimer bound to CBM complex [plasma membrane] (Canis familiaris)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Canis familiaris)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ubiquitination of NEMO by TRAF6 (Canis familiaris)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Canis familiaris)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Canis familiaris)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Canis familiaris)
C-type lectin receptors (CLRs) (Canis familiaris)
CLEC7A (Dectin-1) signaling (Canis familiaris)
Ubiquitination of NEMO by TRAF6 (Canis familiaris)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Canis familiaris)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Canis familiaris)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Fc epsilon receptor (FCERI) signaling (Canis familiaris)
FCERI mediated NF-kB activation (Canis familiaris)
Ubiquitination of NEMO by TRAF6 (Canis familiaris)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Canis familiaris)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Canis familiaris)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Canis familiaris)
CARMA1 trimer [plasma membrane] (Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Role of LAT2/NTAL/LAB on calcium mobilization (Canis familiaris)
Translocation of PDK1 to Plasma membrane (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Canis familiaris)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Fcgamma receptor (FCGR) dependent phagocytosis (Canis familiaris)
Regulation of actin dynamics for phagocytic cup formation (Canis familiaris)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Canis familiaris)
PI(3,4)P2 [plasma membrane]
Actin filament bound Myosin-X [plasma membrane] (Canis familiaris)
PI(3,4)P2 [plasma membrane]
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Phospholipid metabolism (Canis familiaris)
PI Metabolism (Canis familiaris)
Synthesis of PIPs at the plasma membrane (Canis familiaris)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Canis familiaris)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Canis familiaris)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Canis familiaris)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Canis familiaris)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Canis familiaris)
PI(3,4)P2 [plasma membrane]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Canis familiaris)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Canis familiaris)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Canis familiaris)
PI(3,4)P2 [plasma membrane]
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
Clathrin-mediated endocytosis (Canis familiaris)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Canis familiaris)
PI(3,4)P2 [plasma membrane]
F- and N- BAR domain proteins bind the clathrin-coated pit (Canis familiaris)
PI(3,4)P2 [plasma membrane]
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
TCR signaling (Danio rerio)
Downstream TCR signaling (Danio rerio)
Translocation of PDK1 to Plasma membrane (Danio rerio)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Danio rerio)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Danio rerio)
Fc epsilon receptor (FCERI) signaling (Danio rerio)
Role of LAT2/NTAL/LAB on calcium mobilization (Danio rerio)
Translocation of PDK1 to Plasma membrane (Danio rerio)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Danio rerio)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Metabolism (Danio rerio)
Metabolism of lipids (Danio rerio)
Phospholipid metabolism (Danio rerio)
PI Metabolism (Danio rerio)
Synthesis of PIPs at the plasma membrane (Danio rerio)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Danio rerio)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Danio rerio)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Danio rerio)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Danio rerio)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Danio rerio)
PI(3,4)P2 [plasma membrane]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Danio rerio)
PI(3,4)P2 [plasma membrane]
Immune System (Dictyostelium discoideum)
Adaptive Immune System (Dictyostelium discoideum)
TCR signaling (Dictyostelium discoideum)
Downstream TCR signaling (Dictyostelium discoideum)
Phosphorylation of PKC theta (Dictyostelium discoideum)
PDK1:PIP2,PIP3 [plasma membrane] (Dictyostelium discoideum)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of PDK1 to Plasma membrane (Dictyostelium discoideum)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Dictyostelium discoideum)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Dictyostelium discoideum)
Fc epsilon receptor (FCERI) signaling (Dictyostelium discoideum)
Role of LAT2/NTAL/LAB on calcium mobilization (Dictyostelium discoideum)
Translocation of PDK1 to Plasma membrane (Dictyostelium discoideum)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Dictyostelium discoideum)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Metabolism (Dictyostelium discoideum)
Metabolism of lipids (Dictyostelium discoideum)
Phospholipid metabolism (Dictyostelium discoideum)
PI Metabolism (Dictyostelium discoideum)
Synthesis of PIPs at the plasma membrane (Dictyostelium discoideum)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Dictyostelium discoideum)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Dictyostelium discoideum)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Dictyostelium discoideum)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Dictyostelium discoideum)
PI(3,4)P2 [plasma membrane]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Dictyostelium discoideum)
PI(3,4)P2 [plasma membrane]
Vesicle-mediated transport (Dictyostelium discoideum)
Membrane Trafficking (Dictyostelium discoideum)
Clathrin-mediated endocytosis (Dictyostelium discoideum)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Dictyostelium discoideum)
PI(3,4)P2 [plasma membrane]
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
TCR signaling (Drosophila melanogaster)
Downstream TCR signaling (Drosophila melanogaster)
Phosphorylation of PKC theta (Drosophila melanogaster)
PDK1:PIP2,PIP3 [plasma membrane] (Drosophila melanogaster)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of PDK1 to Plasma membrane (Drosophila melanogaster)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Drosophila melanogaster)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Drosophila melanogaster)
Fc epsilon receptor (FCERI) signaling (Drosophila melanogaster)
Role of LAT2/NTAL/LAB on calcium mobilization (Drosophila melanogaster)
Translocation of PDK1 to Plasma membrane (Drosophila melanogaster)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Drosophila melanogaster)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Metabolism (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Phospholipid metabolism (Drosophila melanogaster)
PI Metabolism (Drosophila melanogaster)
Synthesis of PIPs at the plasma membrane (Drosophila melanogaster)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Drosophila melanogaster)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Drosophila melanogaster)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Drosophila melanogaster)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Drosophila melanogaster)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Drosophila melanogaster)
PI(3,4)P2 [plasma membrane]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Drosophila melanogaster)
PI(3,4)P2 [plasma membrane]
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
Clathrin-mediated endocytosis (Drosophila melanogaster)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Drosophila melanogaster)
PI(3,4)P2 [plasma membrane]
F- and N- BAR domain proteins bind the clathrin-coated pit (Drosophila melanogaster)
PI(3,4)P2 [plasma membrane]
Extracellular matrix organization (Gallus gallus)
Invadopodia formation (Gallus gallus)
SH3PXD2A binds ADAM12,ADAM15,ADAM19 (Gallus gallus)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Gallus gallus)
PI(3,4)P2 [plasma membrane]
SH3PXD2A:PI(3,4)P2:ADAM12,ADAM15,ADAM19 [plasma membrane] (Gallus gallus)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Gallus gallus)
PI(3,4)P2 [plasma membrane]
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
TCR signaling (Gallus gallus)
Downstream TCR signaling (Gallus gallus)
Activation of TAK1-TAB2 complex (Gallus gallus)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Gallus gallus)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Gallus gallus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Gallus gallus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Gallus gallus)
CARMA1 trimer [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Gallus gallus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Gallus gallus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Gallus gallus)
CARMA1 trimer [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Hydrolysis of PIP3 to PI(3,4)P2 (Gallus gallus)
PI(3,4)P2 [plasma membrane]
Interaction and oligomerization of MALT1 to Bcl10 (Gallus gallus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Gallus gallus)
CARMA1 trimer [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Gallus gallus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Gallus gallus)
CARMA1 trimer [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Interaction of Bcl10 to CARMA1 (Gallus gallus)
Bcl10 bound to CARMA1 [plasma membrane] (Gallus gallus)
CARMA1 trimer [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of Bcl10 (Gallus gallus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Gallus gallus)
CARMA1 trimer [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Gallus gallus)
CARMA1 trimer [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of CARMA1 (Gallus gallus)
Activated CARMA1 [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of Bcl10 (Gallus gallus)
Bcl10 bound to CARMA1 [plasma membrane] (Gallus gallus)
CARMA1 trimer [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Gallus gallus)
CARMA1 trimer [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of CARMA1 to Plasma membrane (Gallus gallus)
CARMA1 bound to PDK1 [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of PDK1 to Plasma membrane (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of TRAF6 to CBM complex (Gallus gallus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Gallus gallus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Gallus gallus)
CARMA1 trimer [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
TRAF6 trimer bound to CBM complex [plasma membrane] (Gallus gallus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Gallus gallus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Gallus gallus)
CARMA1 trimer [plasma membrane] (Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Gallus gallus)
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
Role of LAT2/NTAL/LAB on calcium mobilization (Gallus gallus)
Translocation of PDK1 to Plasma membrane (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Gallus gallus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Metabolism (Gallus gallus)
Metabolism of lipids (Gallus gallus)
Phospholipid metabolism (Gallus gallus)
PI Metabolism (Gallus gallus)
Synthesis of PIPs at the plasma membrane (Gallus gallus)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Gallus gallus)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Gallus gallus)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Gallus gallus)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Gallus gallus)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Gallus gallus)
PI(3,4)P2 [plasma membrane]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Gallus gallus)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Gallus gallus)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Gallus gallus)
PI(3,4)P2 [plasma membrane]
Vesicle-mediated transport (Gallus gallus)
Membrane Trafficking (Gallus gallus)
Clathrin-mediated endocytosis (Gallus gallus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Gallus gallus)
PI(3,4)P2 [plasma membrane]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Parasite infection (Homo sapiens)
Leishmania phagocytosis (Homo sapiens)
FCGR3A-mediated phagocytosis (Homo sapiens)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)
PI(3,4)P2 [plasma membrane]
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
PI(3,4)P2 [plasma membrane]
Extracellular matrix organization (Homo sapiens)
Invadopodia formation (Homo sapiens)
SH3PXD2A binds ADAM12,ADAM15,ADAM19 (Homo sapiens)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Homo sapiens)
PI(3,4)P2 [plasma membrane]
SH3PXD2A:PI(3,4)P2:ADAM12,ADAM15,ADAM19 [plasma membrane] (Homo sapiens)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Homo sapiens)
PI(3,4)P2 [plasma membrane]
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
TCR signaling (Homo sapiens)
Downstream TCR signaling (Homo sapiens)
Activation of IKK complex (Homo sapiens)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Homo sapiens)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Activation of TAK1-TAB2 complex (Homo sapiens)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Homo sapiens)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Auto-ubiquitination of TRAF6 (Homo sapiens)
TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Hydrolysis of PIP3 to PI(3,4)P2 (Homo sapiens)
PI(3,4)P2 [plasma membrane]
Interaction and oligomerization of MALT1 to Bcl10 (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Interaction of Bcl10 to CARMA1 (Homo sapiens)
Bcl10 bound to CARMA1 [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of Bcl10 (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of CARMA1 (Homo sapiens)
Activated CARMA1 [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of Bcl10 (Homo sapiens)
Bcl10 bound to CARMA1 [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of CARMA1 (Homo sapiens)
Activated CARMA1 [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 bound to PDK1 [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of PKC theta (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of CARMA1 to Plasma membrane (Homo sapiens)
CARMA1 bound to PDK1 [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of PDK1 to Plasma membrane (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of TRAF6 to CBM complex (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ubiquitination of NEMO by TRAF6 (Homo sapiens)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Homo sapiens)
C-type lectin receptors (CLRs) (Homo sapiens)
CLEC7A (Dectin-1) signaling (Homo sapiens)
Ubiquitination of NEMO by TRAF6 (Homo sapiens)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Fc epsilon receptor (FCERI) signaling (Homo sapiens)
FCERI mediated NF-kB activation (Homo sapiens)
Ubiquitination of NEMO by TRAF6 (Homo sapiens)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Role of LAT2/NTAL/LAB on calcium mobilization (Homo sapiens)
Translocation of PDK1 to Plasma membrane (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)
PI(3,4)P2 [plasma membrane]
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
PI(3,4)P2 [plasma membrane]
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
PIPs transport between plasma and early endosome membranes (Homo sapiens)
PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane (Homo sapiens)
PI(3,4)P2 [plasma membrane]
Synthesis of PIPs at the plasma membrane (Homo sapiens)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Homo sapiens)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Homo sapiens)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Homo sapiens)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Homo sapiens)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Homo sapiens)
PI(3,4)P2 [plasma membrane]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Homo sapiens)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Homo sapiens)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Homo sapiens)
PI(3,4)P2 [plasma membrane]
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Homo sapiens)
PI(3,4)P2 [plasma membrane]
F- and N- BAR domain proteins bind the clathrin-coated pit (Homo sapiens)
PI(3,4)P2 [plasma membrane]
Extracellular matrix organization (Mus musculus)
Invadopodia formation (Mus musculus)
SH3PXD2A binds ADAM12,ADAM15,ADAM19 (Mus musculus)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Mus musculus)
PI(3,4)P2 [plasma membrane]
SH3PXD2A:PI(3,4)P2:ADAM12,ADAM15,ADAM19 [plasma membrane] (Mus musculus)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Mus musculus)
PI(3,4)P2 [plasma membrane]
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
TCR signaling (Mus musculus)
Downstream TCR signaling (Mus musculus)
Activation of IKK complex (Mus musculus)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Mus musculus)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Mus musculus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Mus musculus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Activation of TAK1-TAB2 complex (Mus musculus)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Mus musculus)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Mus musculus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Mus musculus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Mus musculus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Mus musculus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Auto-ubiquitination of TRAF6 (Mus musculus)
TRAF6 trimer bound to CBM complex [plasma membrane] (Mus musculus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Mus musculus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Mus musculus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Mus musculus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Hydrolysis of PIP3 to PI(3,4)P2 (Mus musculus)
PI(3,4)P2 [plasma membrane]
Interaction and oligomerization of MALT1 to Bcl10 (Mus musculus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Mus musculus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Interaction of Bcl10 to CARMA1 (Mus musculus)
Bcl10 bound to CARMA1 [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of Bcl10 (Mus musculus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of CARMA1 (Mus musculus)
Activated CARMA1 [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of Bcl10 (Mus musculus)
Bcl10 bound to CARMA1 [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of CARMA1 (Mus musculus)
Activated CARMA1 [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 bound to PDK1 [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of PKC theta (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of CARMA1 to Plasma membrane (Mus musculus)
CARMA1 bound to PDK1 [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of PDK1 to Plasma membrane (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of TRAF6 to CBM complex (Mus musculus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Mus musculus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
TRAF6 trimer bound to CBM complex [plasma membrane] (Mus musculus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Mus musculus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ubiquitination of NEMO by TRAF6 (Mus musculus)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Mus musculus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Mus musculus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Mus musculus)
C-type lectin receptors (CLRs) (Mus musculus)
CLEC7A (Dectin-1) signaling (Mus musculus)
Ubiquitination of NEMO by TRAF6 (Mus musculus)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Mus musculus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Mus musculus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Fc epsilon receptor (FCERI) signaling (Mus musculus)
FCERI mediated NF-kB activation (Mus musculus)
Ubiquitination of NEMO by TRAF6 (Mus musculus)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Mus musculus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Mus musculus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Mus musculus)
CARMA1 trimer [plasma membrane] (Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Role of LAT2/NTAL/LAB on calcium mobilization (Mus musculus)
Translocation of PDK1 to Plasma membrane (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Mus musculus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Fcgamma receptor (FCGR) dependent phagocytosis (Mus musculus)
Regulation of actin dynamics for phagocytic cup formation (Mus musculus)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Mus musculus)
PI(3,4)P2 [plasma membrane]
Actin filament bound Myosin-X [plasma membrane] (Mus musculus)
PI(3,4)P2 [plasma membrane]
Metabolism (Mus musculus)
Metabolism of lipids (Mus musculus)
Phospholipid metabolism (Mus musculus)
PI Metabolism (Mus musculus)
Synthesis of PIPs at the plasma membrane (Mus musculus)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Mus musculus)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Mus musculus)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Mus musculus)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Mus musculus)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Mus musculus)
PI(3,4)P2 [plasma membrane]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Mus musculus)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Mus musculus)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Mus musculus)
PI(3,4)P2 [plasma membrane]
Vesicle-mediated transport (Mus musculus)
Membrane Trafficking (Mus musculus)
Clathrin-mediated endocytosis (Mus musculus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Mus musculus)
PI(3,4)P2 [plasma membrane]
F- and N- BAR domain proteins bind the clathrin-coated pit (Mus musculus)
PI(3,4)P2 [plasma membrane]
Immune System (Plasmodium falciparum)
Adaptive Immune System (Plasmodium falciparum)
TCR signaling (Plasmodium falciparum)
Downstream TCR signaling (Plasmodium falciparum)
Translocation of PDK1 to Plasma membrane (Plasmodium falciparum)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Plasmodium falciparum)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Plasmodium falciparum)
Fc epsilon receptor (FCERI) signaling (Plasmodium falciparum)
Role of LAT2/NTAL/LAB on calcium mobilization (Plasmodium falciparum)
Translocation of PDK1 to Plasma membrane (Plasmodium falciparum)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Plasmodium falciparum)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Metabolism (Plasmodium falciparum)
Metabolism of lipids (Plasmodium falciparum)
Phospholipid metabolism (Plasmodium falciparum)
PI Metabolism (Plasmodium falciparum)
Synthesis of PIPs at the plasma membrane (Plasmodium falciparum)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Plasmodium falciparum)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Plasmodium falciparum)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Plasmodium falciparum)
PI(3,4)P2 [plasma membrane]
Extracellular matrix organization (Rattus norvegicus)
Invadopodia formation (Rattus norvegicus)
SH3PXD2A binds ADAM12,ADAM15,ADAM19 (Rattus norvegicus)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
SH3PXD2A:PI(3,4)P2:ADAM12,ADAM15,ADAM19 [plasma membrane] (Rattus norvegicus)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
TCR signaling (Rattus norvegicus)
Downstream TCR signaling (Rattus norvegicus)
Activation of IKK complex (Rattus norvegicus)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Rattus norvegicus)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Rattus norvegicus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Rattus norvegicus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Rattus norvegicus)
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Activation of TAK1-TAB2 complex (Rattus norvegicus)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Rattus norvegicus)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Rattus norvegicus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Rattus norvegicus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Rattus norvegicus)
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Rattus norvegicus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Rattus norvegicus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Rattus norvegicus)
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Hydrolysis of PIP3 to PI(3,4)P2 (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
Interaction and oligomerization of MALT1 to Bcl10 (Rattus norvegicus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Rattus norvegicus)
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Rattus norvegicus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Rattus norvegicus)
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Interaction of Bcl10 to CARMA1 (Rattus norvegicus)
Bcl10 bound to CARMA1 [plasma membrane] (Rattus norvegicus)
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of Bcl10 (Rattus norvegicus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Rattus norvegicus)
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Rattus norvegicus)
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of CARMA1 (Rattus norvegicus)
Activated CARMA1 [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of Bcl10 (Rattus norvegicus)
Bcl10 bound to CARMA1 [plasma membrane] (Rattus norvegicus)
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Rattus norvegicus)
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of CARMA1 (Rattus norvegicus)
Activated CARMA1 [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 bound to PDK1 [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of PKC theta (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of CARMA1 to Plasma membrane (Rattus norvegicus)
CARMA1 bound to PDK1 [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of PDK1 to Plasma membrane (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of TRAF6 to CBM complex (Rattus norvegicus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Rattus norvegicus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Rattus norvegicus)
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
TRAF6 trimer bound to CBM complex [plasma membrane] (Rattus norvegicus)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Rattus norvegicus)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Rattus norvegicus)
CARMA1 trimer [plasma membrane] (Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Rattus norvegicus)
Fc epsilon receptor (FCERI) signaling (Rattus norvegicus)
Role of LAT2/NTAL/LAB on calcium mobilization (Rattus norvegicus)
Translocation of PDK1 to Plasma membrane (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Rattus norvegicus)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Fcgamma receptor (FCGR) dependent phagocytosis (Rattus norvegicus)
Regulation of actin dynamics for phagocytic cup formation (Rattus norvegicus)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
Actin filament bound Myosin-X [plasma membrane] (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Phospholipid metabolism (Rattus norvegicus)
PI Metabolism (Rattus norvegicus)
Synthesis of PIPs at the plasma membrane (Rattus norvegicus)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
Vesicle-mediated transport (Rattus norvegicus)
Membrane Trafficking (Rattus norvegicus)
Clathrin-mediated endocytosis (Rattus norvegicus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
F- and N- BAR domain proteins bind the clathrin-coated pit (Rattus norvegicus)
PI(3,4)P2 [plasma membrane]
Immune System (Saccharomyces cerevisiae)
Adaptive Immune System (Saccharomyces cerevisiae)
TCR signaling (Saccharomyces cerevisiae)
Downstream TCR signaling (Saccharomyces cerevisiae)
Phosphorylation of PKC theta (Saccharomyces cerevisiae)
PDK1:PIP2,PIP3 [plasma membrane] (Saccharomyces cerevisiae)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of PDK1 to Plasma membrane (Saccharomyces cerevisiae)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Saccharomyces cerevisiae)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Saccharomyces cerevisiae)
Fc epsilon receptor (FCERI) signaling (Saccharomyces cerevisiae)
Role of LAT2/NTAL/LAB on calcium mobilization (Saccharomyces cerevisiae)
Translocation of PDK1 to Plasma membrane (Saccharomyces cerevisiae)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Saccharomyces cerevisiae)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Metabolism (Saccharomyces cerevisiae)
Metabolism of lipids (Saccharomyces cerevisiae)
Phospholipid metabolism (Saccharomyces cerevisiae)
PI Metabolism (Saccharomyces cerevisiae)
Synthesis of PIPs at the plasma membrane (Saccharomyces cerevisiae)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Saccharomyces cerevisiae)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Saccharomyces cerevisiae)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Saccharomyces cerevisiae)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Saccharomyces cerevisiae)
PI(3,4)P2 [plasma membrane]
Extracellular matrix organization (Schizosaccharomyces pombe)
Invadopodia formation (Schizosaccharomyces pombe)
SH3PXD2A binds ADAM12,ADAM15,ADAM19 (Schizosaccharomyces pombe)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Schizosaccharomyces pombe)
PI(3,4)P2 [plasma membrane]
SH3PXD2A:PI(3,4)P2:ADAM12,ADAM15,ADAM19 [plasma membrane] (Schizosaccharomyces pombe)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Schizosaccharomyces pombe)
PI(3,4)P2 [plasma membrane]
Immune System (Schizosaccharomyces pombe)
Adaptive Immune System (Schizosaccharomyces pombe)
TCR signaling (Schizosaccharomyces pombe)
Downstream TCR signaling (Schizosaccharomyces pombe)
Phosphorylation of PKC theta (Schizosaccharomyces pombe)
PDK1:PIP2,PIP3 [plasma membrane] (Schizosaccharomyces pombe)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of PDK1 to Plasma membrane (Schizosaccharomyces pombe)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Schizosaccharomyces pombe)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Schizosaccharomyces pombe)
Fc epsilon receptor (FCERI) signaling (Schizosaccharomyces pombe)
Role of LAT2/NTAL/LAB on calcium mobilization (Schizosaccharomyces pombe)
Translocation of PDK1 to Plasma membrane (Schizosaccharomyces pombe)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Schizosaccharomyces pombe)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Metabolism (Schizosaccharomyces pombe)
Metabolism of lipids (Schizosaccharomyces pombe)
Phospholipid metabolism (Schizosaccharomyces pombe)
PI Metabolism (Schizosaccharomyces pombe)
Synthesis of PIPs at the plasma membrane (Schizosaccharomyces pombe)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Schizosaccharomyces pombe)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Schizosaccharomyces pombe)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Schizosaccharomyces pombe)
PI(3,4)P2 [plasma membrane]
Extracellular matrix organization (Sus scrofa)
Invadopodia formation (Sus scrofa)
SH3PXD2A binds ADAM12,ADAM15,ADAM19 (Sus scrofa)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Sus scrofa)
PI(3,4)P2 [plasma membrane]
SH3PXD2A:PI(3,4)P2:ADAM12,ADAM15,ADAM19 [plasma membrane] (Sus scrofa)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Sus scrofa)
PI(3,4)P2 [plasma membrane]
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
TCR signaling (Sus scrofa)
Downstream TCR signaling (Sus scrofa)
Activation of IKK complex (Sus scrofa)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Sus scrofa)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Sus scrofa)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Sus scrofa)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Activation of TAK1-TAB2 complex (Sus scrofa)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Sus scrofa)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Sus scrofa)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Sus scrofa)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Sus scrofa)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Sus scrofa)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Auto-ubiquitination of TRAF6 (Sus scrofa)
TRAF6 trimer bound to CBM complex [plasma membrane] (Sus scrofa)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Sus scrofa)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Sus scrofa)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Sus scrofa)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Hydrolysis of PIP3 to PI(3,4)P2 (Sus scrofa)
PI(3,4)P2 [plasma membrane]
Interaction and oligomerization of MALT1 to Bcl10 (Sus scrofa)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Sus scrofa)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Interaction of Bcl10 to CARMA1 (Sus scrofa)
Bcl10 bound to CARMA1 [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of Bcl10 (Sus scrofa)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Oligomerization of CARMA1 (Sus scrofa)
Activated CARMA1 [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of Bcl10 (Sus scrofa)
Bcl10 bound to CARMA1 [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of CARMA1 (Sus scrofa)
Activated CARMA1 [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 bound to PDK1 [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Phosphorylation of PKC theta (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of CARMA1 to Plasma membrane (Sus scrofa)
CARMA1 bound to PDK1 [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of PDK1 to Plasma membrane (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of TRAF6 to CBM complex (Sus scrofa)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Sus scrofa)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
TRAF6 trimer bound to CBM complex [plasma membrane] (Sus scrofa)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Sus scrofa)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Ubiquitination of NEMO by TRAF6 (Sus scrofa)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Sus scrofa)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Sus scrofa)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Sus scrofa)
C-type lectin receptors (CLRs) (Sus scrofa)
CLEC7A (Dectin-1) signaling (Sus scrofa)
Ubiquitination of NEMO by TRAF6 (Sus scrofa)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Sus scrofa)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Sus scrofa)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Fc epsilon receptor (FCERI) signaling (Sus scrofa)
FCERI mediated NF-kB activation (Sus scrofa)
Ubiquitination of NEMO by TRAF6 (Sus scrofa)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Sus scrofa)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Sus scrofa)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Sus scrofa)
CARMA1 trimer [plasma membrane] (Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Role of LAT2/NTAL/LAB on calcium mobilization (Sus scrofa)
Translocation of PDK1 to Plasma membrane (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Sus scrofa)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Fcgamma receptor (FCGR) dependent phagocytosis (Sus scrofa)
Regulation of actin dynamics for phagocytic cup formation (Sus scrofa)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Sus scrofa)
PI(3,4)P2 [plasma membrane]
Actin filament bound Myosin-X [plasma membrane] (Sus scrofa)
PI(3,4)P2 [plasma membrane]
Metabolism (Sus scrofa)
Metabolism of lipids (Sus scrofa)
Phospholipid metabolism (Sus scrofa)
PI Metabolism (Sus scrofa)
Synthesis of PIPs at the plasma membrane (Sus scrofa)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Sus scrofa)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Sus scrofa)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Sus scrofa)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Sus scrofa)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Sus scrofa)
PI(3,4)P2 [plasma membrane]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Sus scrofa)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Sus scrofa)
PI(3,4)P2 [plasma membrane]
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Sus scrofa)
PI(3,4)P2 [plasma membrane]
Vesicle-mediated transport (Sus scrofa)
Membrane Trafficking (Sus scrofa)
Clathrin-mediated endocytosis (Sus scrofa)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Sus scrofa)
PI(3,4)P2 [plasma membrane]
F- and N- BAR domain proteins bind the clathrin-coated pit (Sus scrofa)
PI(3,4)P2 [plasma membrane]
Immune System (Xenopus tropicalis)
Adaptive Immune System (Xenopus tropicalis)
TCR signaling (Xenopus tropicalis)
Downstream TCR signaling (Xenopus tropicalis)
Hydrolysis of PIP3 to PI(3,4)P2 (Xenopus tropicalis)
PI(3,4)P2 [plasma membrane]
Oligomerization of CARMA1 (Xenopus tropicalis)
Activated CARMA1 [plasma membrane] (Xenopus tropicalis)
PDK1:PIP2,PIP3 [plasma membrane] (Xenopus tropicalis)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
CARMA1 trimer [plasma membrane] (Xenopus tropicalis)
PDK1:PIP2,PIP3 [plasma membrane] (Xenopus tropicalis)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of CARMA1 to Plasma membrane (Xenopus tropicalis)
CARMA1 bound to PDK1 [plasma membrane] (Xenopus tropicalis)
PDK1:PIP2,PIP3 [plasma membrane] (Xenopus tropicalis)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Xenopus tropicalis)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Translocation of PDK1 to Plasma membrane (Xenopus tropicalis)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Xenopus tropicalis)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Innate Immune System (Xenopus tropicalis)
Fc epsilon receptor (FCERI) signaling (Xenopus tropicalis)
Role of LAT2/NTAL/LAB on calcium mobilization (Xenopus tropicalis)
Translocation of PDK1 to Plasma membrane (Xenopus tropicalis)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
PDK1:PIP2,PIP3 [plasma membrane] (Xenopus tropicalis)
PIP3, PI(3,4)P2 [plasma membrane]
PI(3,4)P2 [plasma membrane]
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Phospholipid metabolism (Xenopus tropicalis)
PI Metabolism (Xenopus tropicalis)
Synthesis of PIPs at the plasma membrane (Xenopus tropicalis)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Xenopus tropicalis)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Xenopus tropicalis)
PI(3,4)P2 [plasma membrane]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Xenopus tropicalis)
PI(3,4)P2 [plasma membrane]
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Xenopus tropicalis)
PI(3,4)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Xenopus tropicalis)
PI(3,4)P2 [plasma membrane]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Xenopus tropicalis)
PI(3,4)P2 [plasma membrane]
External Reference Information
External Reference
1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate [ChEBI:16152]
Participates
as a component of
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Bos taurus)
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Mus musculus)
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Canis familiaris)
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Rattus norvegicus)
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Gallus gallus)
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Sus scrofa)
PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Homo sapiens)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Mus musculus)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Rattus norvegicus)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Schizosaccharomyces pombe)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Sus scrofa)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Saccharomyces cerevisiae)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Gallus gallus)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Danio rerio)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Canis familiaris)
SH3PXD2A:PI(3,4)P2 [plasma membrane] (Homo sapiens)
Actin filament bound Myosin-X [plasma membrane] (Canis familiaris)
Actin filament bound Myosin-X [plasma membrane] (Mus musculus)
Actin filament bound Myosin-X [plasma membrane] (Sus scrofa)
Actin filament bound Myosin-X [plasma membrane] (Rattus norvegicus)
Actin filament bound Myosin-X [plasma membrane] (Bos taurus)
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
as an input of
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Gallus gallus)
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Sus scrofa)
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Bos taurus)
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Canis familiaris)
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Rattus norvegicus)
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Mus musculus)
PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Homo sapiens)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Sus scrofa)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Bos taurus)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Canis familiaris)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Rattus norvegicus)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Mus musculus)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Plasmodium falciparum)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Canis familiaris)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Saccharomyces cerevisiae)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Saccharomyces cerevisiae)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Schizosaccharomyces pombe)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Schizosaccharomyces pombe)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Dictyostelium discoideum)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Dictyostelium discoideum)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Caenorhabditis elegans)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Caenorhabditis elegans)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Caenorhabditis elegans)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Drosophila melanogaster)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Drosophila melanogaster)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Drosophila melanogaster)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Gallus gallus)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Gallus gallus)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Gallus gallus)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Xenopus tropicalis)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Mus musculus)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Homo sapiens)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Homo sapiens)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Homo sapiens)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Mus musculus)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Rattus norvegicus)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Rattus norvegicus)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Rattus norvegicus)
PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane (Homo sapiens)
PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane (Mus musculus)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Canis familiaris)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Canis familiaris)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Bos taurus)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Bos taurus)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Bos taurus)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Mus musculus)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Sus scrofa)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Sus scrofa)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Sus scrofa)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Danio rerio)
PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Danio rerio)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Danio rerio)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Xenopus tropicalis)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Xenopus tropicalis)
as an output of
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Dictyostelium discoideum)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Caenorhabditis elegans)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Drosophila melanogaster)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Gallus gallus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Sus scrofa)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Bos taurus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Canis familiaris)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Rattus norvegicus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Mus musculus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Homo sapiens)
Hydrolysis of PIP3 to PI(3,4)P2 (Gallus gallus)
Hydrolysis of PIP3 to PI(3,4)P2 (Xenopus tropicalis)
Hydrolysis of PIP3 to PI(3,4)P2 (Sus scrofa)
Hydrolysis of PIP3 to PI(3,4)P2 (Bos taurus)
Hydrolysis of PIP3 to PI(3,4)P2 (Canis familiaris)
Hydrolysis of PIP3 to PI(3,4)P2 (Rattus norvegicus)
Hydrolysis of PIP3 to PI(3,4)P2 (Mus musculus)
Hydrolysis of PIP3 to PI(3,4)P2 (Homo sapiens)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Plasmodium falciparum)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Plasmodium falciparum)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Canis familiaris)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Saccharomyces cerevisiae)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Saccharomyces cerevisiae)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Schizosaccharomyces pombe)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Dictyostelium discoideum)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Dictyostelium discoideum)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Dictyostelium discoideum)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Caenorhabditis elegans)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Caenorhabditis elegans)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Caenorhabditis elegans)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Drosophila melanogaster)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Drosophila melanogaster)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Drosophila melanogaster)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Gallus gallus)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Gallus gallus)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Gallus gallus)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Xenopus tropicalis)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Xenopus tropicalis)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Mus musculus)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Homo sapiens)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Homo sapiens)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Homo sapiens)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Mus musculus)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Rattus norvegicus)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Rattus norvegicus)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Rattus norvegicus)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Canis familiaris)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Canis familiaris)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Bos taurus)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Bos taurus)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Bos taurus)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Mus musculus)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Sus scrofa)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Sus scrofa)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Sus scrofa)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Danio rerio)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Danio rerio)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Danio rerio)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Xenopus tropicalis)
as a member of
PIP3, PI(3,4)P2 [plasma membrane]
This entity regulates
Positively
F- and N- BAR domain proteins bind the clathrin-coated pit
(Drosophila melanogaster)
F- and N- BAR domain proteins bind the clathrin-coated pit
(Sus scrofa)
F- and N- BAR domain proteins bind the clathrin-coated pit
(Bos taurus)
F- and N- BAR domain proteins bind the clathrin-coated pit
(Canis familiaris)
F- and N- BAR domain proteins bind the clathrin-coated pit
(Rattus norvegicus)
F- and N- BAR domain proteins bind the clathrin-coated pit
(Mus musculus)
F- and N- BAR domain proteins bind the clathrin-coated pit
(Homo sapiens)
Other forms of this molecule
PI(3,4)P2 [early endosome membrane]
PI(3,4)P2 [Golgi membrane]