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VitC [endoplasmic reticulum lumen]
Stable Identifier
R-ALL-1981146
Type
Chemical Compound [SimpleEntity]
Compartment
endoplasmic reticulum lumen
Synonyms
Ascorbate, L-ascorbic acid
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Extracellular matrix organization (Bos taurus)
Collagen formation (Bos taurus)
Collagen biosynthesis and modifying enzymes (Bos taurus)
Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Bos taurus)
Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Bos taurus)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Bos taurus)
VitC [endoplasmic reticulum lumen]
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Bos taurus)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Bos taurus)
VitC [endoplasmic reticulum lumen]
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Bos taurus)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Bos taurus)
VitC [endoplasmic reticulum lumen]
Extracellular matrix organization (Caenorhabditis elegans)
Collagen formation (Caenorhabditis elegans)
Collagen biosynthesis and modifying enzymes (Caenorhabditis elegans)
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Caenorhabditis elegans)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Caenorhabditis elegans)
VitC [endoplasmic reticulum lumen]
Extracellular matrix organization (Canis familiaris)
Collagen formation (Canis familiaris)
Collagen biosynthesis and modifying enzymes (Canis familiaris)
Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Canis familiaris)
Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Canis familiaris)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Canis familiaris)
VitC [endoplasmic reticulum lumen]
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Canis familiaris)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Canis familiaris)
VitC [endoplasmic reticulum lumen]
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Canis familiaris)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Canis familiaris)
VitC [endoplasmic reticulum lumen]
Extracellular matrix organization (Danio rerio)
Collagen formation (Danio rerio)
Collagen biosynthesis and modifying enzymes (Danio rerio)
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Danio rerio)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Danio rerio)
VitC [endoplasmic reticulum lumen]
Extracellular matrix organization (Gallus gallus)
Collagen formation (Gallus gallus)
Collagen biosynthesis and modifying enzymes (Gallus gallus)
Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Gallus gallus)
Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Gallus gallus)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Gallus gallus)
VitC [endoplasmic reticulum lumen]
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Gallus gallus)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Gallus gallus)
VitC [endoplasmic reticulum lumen]
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Gallus gallus)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Gallus gallus)
VitC [endoplasmic reticulum lumen]
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Homo sapiens)
VitC [endoplasmic reticulum lumen]
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Homo sapiens)
VitC [endoplasmic reticulum lumen]
P3HB binds 4-Hyp-collagen propeptides (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Homo sapiens)
VitC [endoplasmic reticulum lumen]
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Homo sapiens)
VitC [endoplasmic reticulum lumen]
Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides dissociates (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Homo sapiens)
VitC [endoplasmic reticulum lumen]
Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Homo sapiens)
VitC [endoplasmic reticulum lumen]
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Homo sapiens)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Homo sapiens)
VitC [endoplasmic reticulum lumen]
Extracellular matrix organization (Mus musculus)
Collagen formation (Mus musculus)
Collagen biosynthesis and modifying enzymes (Mus musculus)
Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Mus musculus)
Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Mus musculus)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Mus musculus)
VitC [endoplasmic reticulum lumen]
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Mus musculus)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Mus musculus)
VitC [endoplasmic reticulum lumen]
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Mus musculus)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Mus musculus)
VitC [endoplasmic reticulum lumen]
Extracellular matrix organization (Rattus norvegicus)
Collagen formation (Rattus norvegicus)
Collagen biosynthesis and modifying enzymes (Rattus norvegicus)
Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Rattus norvegicus)
Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Rattus norvegicus)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Rattus norvegicus)
VitC [endoplasmic reticulum lumen]
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Rattus norvegicus)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Rattus norvegicus)
VitC [endoplasmic reticulum lumen]
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Rattus norvegicus)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Rattus norvegicus)
VitC [endoplasmic reticulum lumen]
Extracellular matrix organization (Sus scrofa)
Collagen formation (Sus scrofa)
Collagen biosynthesis and modifying enzymes (Sus scrofa)
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Sus scrofa)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Sus scrofa)
VitC [endoplasmic reticulum lumen]
Extracellular matrix organization (Xenopus tropicalis)
Collagen formation (Xenopus tropicalis)
Collagen biosynthesis and modifying enzymes (Xenopus tropicalis)
Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Xenopus tropicalis)
Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Xenopus tropicalis)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Xenopus tropicalis)
VitC [endoplasmic reticulum lumen]
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Xenopus tropicalis)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Xenopus tropicalis)
VitC [endoplasmic reticulum lumen]
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Xenopus tropicalis)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Xenopus tropicalis)
VitC [endoplasmic reticulum lumen]
External Reference Information
External Reference
L-ascorbic acid [ChEBI:29073]
Participates
as a component of
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Mus musculus)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Xenopus tropicalis)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Rattus norvegicus)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Gallus gallus)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Bos taurus)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Canis familiaris)
Prolyl 3-hydroxylases:Fe2+ [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Gallus gallus)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Canis familiaris)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Mus musculus)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Rattus norvegicus)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Sus scrofa)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Danio rerio)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Bos taurus)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Xenopus tropicalis)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Homo sapiens)
Cross References
Guide to Pharmacology - Ligands
4781
COMPOUND
C00072
HMDB Metabolite
HMDB0000044
ZINC
000100006770
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