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FOLA [cytosol]
Stable Identifier
R-ALL-197965
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Folate, folic acid
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Metabolism of folate and pterines (Bos taurus)
Cytosolic folate export across the plasma membrane (Bos taurus)
FOLA [cytosol]
DHFR dimer reduces FOLA to DHF (Bos taurus)
FOLA [cytosol]
DHFR2 reduces FOLA to DHF (Bos taurus)
FOLA [cytosol]
FOLR2 transports FOLA from extracellular region to cytosol (Bos taurus)
FOLA [cytosol]
SLC46A1 transports FOLA from extracellular region to cytosol (Bos taurus)
FOLA [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Metabolism of folate and pterines (Caenorhabditis elegans)
Cytosolic folate export across the plasma membrane (Caenorhabditis elegans)
FOLA [cytosol]
DHFR dimer reduces FOLA to DHF (Caenorhabditis elegans)
FOLA [cytosol]
DHFR2 reduces FOLA to DHF (Caenorhabditis elegans)
FOLA [cytosol]
SLC46A1 transports FOLA from extracellular region to cytosol (Caenorhabditis elegans)
FOLA [cytosol]
Metabolism (Canis familiaris)
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Metabolism of folate and pterines (Canis familiaris)
Cytosolic folate export across the plasma membrane (Canis familiaris)
FOLA [cytosol]
DHFR dimer reduces FOLA to DHF (Canis familiaris)
FOLA [cytosol]
DHFR2 reduces FOLA to DHF (Canis familiaris)
FOLA [cytosol]
FOLR2 transports FOLA from extracellular region to cytosol (Canis familiaris)
FOLA [cytosol]
SLC46A1 transports FOLA from extracellular region to cytosol (Canis familiaris)
FOLA [cytosol]
Metabolism (Danio rerio)
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Metabolism of folate and pterines (Danio rerio)
Cytosolic folate export across the plasma membrane (Danio rerio)
FOLA [cytosol]
DHFR dimer reduces FOLA to DHF (Danio rerio)
FOLA [cytosol]
DHFR2 reduces FOLA to DHF (Danio rerio)
FOLA [cytosol]
FOLR2 transports FOLA from extracellular region to cytosol (Danio rerio)
FOLA [cytosol]
SLC46A1 transports FOLA from extracellular region to cytosol (Danio rerio)
FOLA [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Metabolism of folate and pterines (Dictyostelium discoideum)
DHFR dimer reduces FOLA to DHF (Dictyostelium discoideum)
FOLA [cytosol]
DHFR2 reduces FOLA to DHF (Dictyostelium discoideum)
FOLA [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Metabolism of folate and pterines (Drosophila melanogaster)
Cytosolic folate export across the plasma membrane (Drosophila melanogaster)
FOLA [cytosol]
DHFR dimer reduces FOLA to DHF (Drosophila melanogaster)
FOLA [cytosol]
DHFR2 reduces FOLA to DHF (Drosophila melanogaster)
FOLA [cytosol]
SLC46A1 transports FOLA from extracellular region to cytosol (Drosophila melanogaster)
FOLA [cytosol]
Metabolism (Gallus gallus)
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Metabolism of folate and pterines (Gallus gallus)
Cytosolic folate export across the plasma membrane (Gallus gallus)
FOLA [cytosol]
DHFR dimer reduces FOLA to DHF (Gallus gallus)
FOLA [cytosol]
DHFR2 reduces FOLA to DHF (Gallus gallus)
FOLA [cytosol]
FOLR2 transports FOLA from extracellular region to cytosol (Gallus gallus)
FOLA [cytosol]
SLC46A1 transports FOLA from extracellular region to cytosol (Gallus gallus)
FOLA [cytosol]
Metabolism (Homo sapiens)
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Metabolism of folate and pterines (Homo sapiens)
Cytosolic folate export across the plasma membrane (Homo sapiens)
FOLA [cytosol]
DHFR dimer reduces FOLA to DHF (Homo sapiens)
FOLA [cytosol]
DHFR2 reduces FOLA to DHF (Homo sapiens)
FOLA [cytosol]
FOLR2 transports FOLA from extracellular region to cytosol (Homo sapiens)
FOLA [cytosol]
SLC46A1 transports FOLA from extracellular region to cytosol (Homo sapiens)
FOLA [cytosol]
Metabolism (Mus musculus)
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Metabolism of folate and pterines (Mus musculus)
Cytosolic folate export across the plasma membrane (Mus musculus)
FOLA [cytosol]
DHFR dimer reduces FOLA to DHF (Mus musculus)
FOLA [cytosol]
DHFR2 reduces FOLA to DHF (Mus musculus)
FOLA [cytosol]
FOLR2 transports FOLA from extracellular region to cytosol (Mus musculus)
FOLA [cytosol]
SLC46A1 transports FOLA from extracellular region to cytosol (Mus musculus)
FOLA [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Metabolism of folate and pterines (Rattus norvegicus)
Cytosolic folate export across the plasma membrane (Rattus norvegicus)
FOLA [cytosol]
DHFR dimer reduces FOLA to DHF (Rattus norvegicus)
FOLA [cytosol]
DHFR2 reduces FOLA to DHF (Rattus norvegicus)
FOLA [cytosol]
FOLR2 transports FOLA from extracellular region to cytosol (Rattus norvegicus)
FOLA [cytosol]
SLC46A1 transports FOLA from extracellular region to cytosol (Rattus norvegicus)
FOLA [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of water-soluble vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of folate and pterines (Saccharomyces cerevisiae)
Cytosolic folate export across the plasma membrane (Saccharomyces cerevisiae)
FOLA [cytosol]
DHFR dimer reduces FOLA to DHF (Saccharomyces cerevisiae)
FOLA [cytosol]
DHFR2 reduces FOLA to DHF (Saccharomyces cerevisiae)
FOLA [cytosol]
SLC46A1 transports FOLA from extracellular region to cytosol (Saccharomyces cerevisiae)
FOLA [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of water-soluble vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of folate and pterines (Schizosaccharomyces pombe)
Cytosolic folate export across the plasma membrane (Schizosaccharomyces pombe)
FOLA [cytosol]
DHFR dimer reduces FOLA to DHF (Schizosaccharomyces pombe)
FOLA [cytosol]
DHFR2 reduces FOLA to DHF (Schizosaccharomyces pombe)
FOLA [cytosol]
SLC46A1 transports FOLA from extracellular region to cytosol (Schizosaccharomyces pombe)
FOLA [cytosol]
Metabolism (Sus scrofa)
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Metabolism of folate and pterines (Sus scrofa)
Cytosolic folate export across the plasma membrane (Sus scrofa)
FOLA [cytosol]
DHFR dimer reduces FOLA to DHF (Sus scrofa)
FOLA [cytosol]
DHFR2 reduces FOLA to DHF (Sus scrofa)
FOLA [cytosol]
FOLR2 transports FOLA from extracellular region to cytosol (Sus scrofa)
FOLA [cytosol]
SLC46A1 transports FOLA from extracellular region to cytosol (Sus scrofa)
FOLA [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of water-soluble vitamins and cofactors (Xenopus tropicalis)
Metabolism of folate and pterines (Xenopus tropicalis)
Cytosolic folate export across the plasma membrane (Xenopus tropicalis)
FOLA [cytosol]
SLC46A1 transports FOLA from extracellular region to cytosol (Xenopus tropicalis)
FOLA [cytosol]
External Reference Information
External Reference
folic acid [ChEBI:27470]
Participates
as an input of
DHFR dimer reduces FOLA to DHF (Saccharomyces cerevisiae)
DHFR dimer reduces FOLA to DHF (Schizosaccharomyces pombe)
DHFR dimer reduces FOLA to DHF (Dictyostelium discoideum)
DHFR dimer reduces FOLA to DHF (Caenorhabditis elegans)
DHFR dimer reduces FOLA to DHF (Drosophila melanogaster)
DHFR dimer reduces FOLA to DHF (Gallus gallus)
DHFR dimer reduces FOLA to DHF (Danio rerio)
DHFR2 reduces FOLA to DHF (Bos taurus)
Cytosolic folate export across the plasma membrane (Homo sapiens)
Cytosolic folate export across the plasma membrane (Mus musculus)
Cytosolic folate export across the plasma membrane (Rattus norvegicus)
Cytosolic folate export across the plasma membrane (Canis familiaris)
Cytosolic folate export across the plasma membrane (Bos taurus)
Cytosolic folate export across the plasma membrane (Sus scrofa)
Cytosolic folate export across the plasma membrane (Danio rerio)
Cytosolic folate export across the plasma membrane (Xenopus tropicalis)
Cytosolic folate export across the plasma membrane (Gallus gallus)
Cytosolic folate export across the plasma membrane (Drosophila melanogaster)
Cytosolic folate export across the plasma membrane (Caenorhabditis elegans)
Cytosolic folate export across the plasma membrane (Schizosaccharomyces pombe)
Cytosolic folate export across the plasma membrane (Saccharomyces cerevisiae)
DHFR2 reduces FOLA to DHF (Homo sapiens)
DHFR2 reduces FOLA to DHF (Mus musculus)
DHFR2 reduces FOLA to DHF (Rattus norvegicus)
DHFR2 reduces FOLA to DHF (Canis familiaris)
DHFR2 reduces FOLA to DHF (Sus scrofa)
DHFR2 reduces FOLA to DHF (Danio rerio)
DHFR2 reduces FOLA to DHF (Gallus gallus)
DHFR2 reduces FOLA to DHF (Drosophila melanogaster)
DHFR2 reduces FOLA to DHF (Caenorhabditis elegans)
DHFR2 reduces FOLA to DHF (Dictyostelium discoideum)
DHFR2 reduces FOLA to DHF (Schizosaccharomyces pombe)
DHFR2 reduces FOLA to DHF (Saccharomyces cerevisiae)
DHFR dimer reduces FOLA to DHF (Bos taurus)
DHFR dimer reduces FOLA to DHF (Homo sapiens)
DHFR dimer reduces FOLA to DHF (Mus musculus)
DHFR dimer reduces FOLA to DHF (Rattus norvegicus)
DHFR dimer reduces FOLA to DHF (Canis familiaris)
DHFR dimer reduces FOLA to DHF (Sus scrofa)
as an output of
FOLR2 transports FOLA from extracellular region to cytosol (Gallus gallus)
FOLR2 transports FOLA from extracellular region to cytosol (Danio rerio)
FOLR2 transports FOLA from extracellular region to cytosol (Sus scrofa)
FOLR2 transports FOLA from extracellular region to cytosol (Bos taurus)
FOLR2 transports FOLA from extracellular region to cytosol (Canis familiaris)
FOLR2 transports FOLA from extracellular region to cytosol (Rattus norvegicus)
FOLR2 transports FOLA from extracellular region to cytosol (Mus musculus)
FOLR2 transports FOLA from extracellular region to cytosol (Homo sapiens)
SLC46A1 transports FOLA from extracellular region to cytosol (Bos taurus)
SLC46A1 transports FOLA from extracellular region to cytosol (Homo sapiens)
SLC46A1 transports FOLA from extracellular region to cytosol (Mus musculus)
SLC46A1 transports FOLA from extracellular region to cytosol (Rattus norvegicus)
SLC46A1 transports FOLA from extracellular region to cytosol (Canis familiaris)
SLC46A1 transports FOLA from extracellular region to cytosol (Sus scrofa)
SLC46A1 transports FOLA from extracellular region to cytosol (Danio rerio)
SLC46A1 transports FOLA from extracellular region to cytosol (Xenopus tropicalis)
SLC46A1 transports FOLA from extracellular region to cytosol (Gallus gallus)
SLC46A1 transports FOLA from extracellular region to cytosol (Drosophila melanogaster)
SLC46A1 transports FOLA from extracellular region to cytosol (Caenorhabditis elegans)
SLC46A1 transports FOLA from extracellular region to cytosol (Schizosaccharomyces pombe)
SLC46A1 transports FOLA from extracellular region to cytosol (Saccharomyces cerevisiae)
Other forms of this molecule
FOLA [extracellular region]
Cross References
Guide to Pharmacology - Ligands
4563
COMPOUND
C00504
HMDB Metabolite
HMDB0000121
ZINC
000008577218
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