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PREG [cytosol]
Stable Identifier
R-ALL-193103
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
pregnenolone
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase II - Conjugation of compounds (Bos taurus)
Cytosolic sulfonation of small molecules (Bos taurus)
SULTs transfer (SO4)2- group to PREG (Bos taurus)
PREG [cytosol]
Metabolism of lipids (Bos taurus)
Metabolism of steroids (Bos taurus)
Metabolism of steroid hormones (Bos taurus)
Androgen biosynthesis (Bos taurus)
CYP17A1 17-hydroxylates PREG (Bos taurus)
PREG [cytosol]
Glucocorticoid biosynthesis (Bos taurus)
CYP17A1 17-hydroxylates PREG (Bos taurus)
PREG [cytosol]
Mineralocorticoid biosynthesis (Bos taurus)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Bos taurus)
PREG [cytosol]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase II - Conjugation of compounds (Caenorhabditis elegans)
Cytosolic sulfonation of small molecules (Caenorhabditis elegans)
SULTs transfer (SO4)2- group to PREG (Caenorhabditis elegans)
PREG [cytosol]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase II - Conjugation of compounds (Canis familiaris)
Cytosolic sulfonation of small molecules (Canis familiaris)
SULTs transfer (SO4)2- group to PREG (Canis familiaris)
PREG [cytosol]
Metabolism of lipids (Canis familiaris)
Metabolism of steroids (Canis familiaris)
Metabolism of steroid hormones (Canis familiaris)
Androgen biosynthesis (Canis familiaris)
CYP17A1 17-hydroxylates PREG (Canis familiaris)
PREG [cytosol]
Glucocorticoid biosynthesis (Canis familiaris)
CYP17A1 17-hydroxylates PREG (Canis familiaris)
PREG [cytosol]
Mineralocorticoid biosynthesis (Canis familiaris)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Canis familiaris)
PREG [cytosol]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase II - Conjugation of compounds (Danio rerio)
Cytosolic sulfonation of small molecules (Danio rerio)
SULTs transfer (SO4)2- group to PREG (Danio rerio)
PREG [cytosol]
Metabolism of lipids (Danio rerio)
Metabolism of steroids (Danio rerio)
Metabolism of steroid hormones (Danio rerio)
Androgen biosynthesis (Danio rerio)
CYP17A1 17-hydroxylates PREG (Danio rerio)
PREG [cytosol]
Glucocorticoid biosynthesis (Danio rerio)
CYP17A1 17-hydroxylates PREG (Danio rerio)
PREG [cytosol]
Mineralocorticoid biosynthesis (Danio rerio)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Danio rerio)
PREG [cytosol]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase II - Conjugation of compounds (Drosophila melanogaster)
Cytosolic sulfonation of small molecules (Drosophila melanogaster)
SULTs transfer (SO4)2- group to PREG (Drosophila melanogaster)
PREG [cytosol]
Metabolism of lipids (Drosophila melanogaster)
Metabolism of steroids (Drosophila melanogaster)
Metabolism of steroid hormones (Drosophila melanogaster)
Mineralocorticoid biosynthesis (Drosophila melanogaster)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Drosophila melanogaster)
PREG [cytosol]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase II - Conjugation of compounds (Gallus gallus)
Cytosolic sulfonation of small molecules (Gallus gallus)
SULTs transfer (SO4)2- group to PREG (Gallus gallus)
PREG [cytosol]
Metabolism of lipids (Gallus gallus)
Metabolism of steroids (Gallus gallus)
Metabolism of steroid hormones (Gallus gallus)
Androgen biosynthesis (Gallus gallus)
CYP17A1 17-hydroxylates PREG (Gallus gallus)
PREG [cytosol]
Glucocorticoid biosynthesis (Gallus gallus)
CYP17A1 17-hydroxylates PREG (Gallus gallus)
PREG [cytosol]
Mineralocorticoid biosynthesis (Gallus gallus)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Gallus gallus)
PREG [cytosol]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Metabolic disorders of biological oxidation enzymes (Homo sapiens)
Defective CYP17A1 causes AH5 (Homo sapiens)
Defective CYP17A1 does not 17-hydroxylate PREG (Homo sapiens)
PREG [cytosol]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Cytosolic sulfonation of small molecules (Homo sapiens)
SULTs transfer (SO4)2- group to PREG (Homo sapiens)
PREG [cytosol]
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Metabolism of steroid hormones (Homo sapiens)
Androgen biosynthesis (Homo sapiens)
CYP17A1 17-hydroxylates PREG (Homo sapiens)
PREG [cytosol]
Glucocorticoid biosynthesis (Homo sapiens)
CYP17A1 17-hydroxylates PREG (Homo sapiens)
PREG [cytosol]
Mineralocorticoid biosynthesis (Homo sapiens)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Homo sapiens)
PREG [cytosol]
Pregnenolone biosynthesis (Homo sapiens)
Pregnenolone translocates from the mitochondrial matrix to the cytosol (Homo sapiens)
PREG [cytosol]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase II - Conjugation of compounds (Mus musculus)
Cytosolic sulfonation of small molecules (Mus musculus)
SULTs transfer (SO4)2- group to PREG (Mus musculus)
PREG [cytosol]
Metabolism of lipids (Mus musculus)
Metabolism of steroids (Mus musculus)
Metabolism of steroid hormones (Mus musculus)
Androgen biosynthesis (Mus musculus)
CYP17A1 17-hydroxylates PREG (Mus musculus)
PREG [cytosol]
Glucocorticoid biosynthesis (Mus musculus)
CYP17A1 17-hydroxylates PREG (Mus musculus)
PREG [cytosol]
Mineralocorticoid biosynthesis (Mus musculus)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Mus musculus)
PREG [cytosol]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase II - Conjugation of compounds (Rattus norvegicus)
Cytosolic sulfonation of small molecules (Rattus norvegicus)
SULTs transfer (SO4)2- group to PREG (Rattus norvegicus)
PREG [cytosol]
Metabolism of lipids (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Metabolism of steroid hormones (Rattus norvegicus)
Androgen biosynthesis (Rattus norvegicus)
CYP17A1 17-hydroxylates PREG (Rattus norvegicus)
PREG [cytosol]
Glucocorticoid biosynthesis (Rattus norvegicus)
CYP17A1 17-hydroxylates PREG (Rattus norvegicus)
PREG [cytosol]
Mineralocorticoid biosynthesis (Rattus norvegicus)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Rattus norvegicus)
PREG [cytosol]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase II - Conjugation of compounds (Sus scrofa)
Cytosolic sulfonation of small molecules (Sus scrofa)
SULTs transfer (SO4)2- group to PREG (Sus scrofa)
PREG [cytosol]
Metabolism of lipids (Sus scrofa)
Metabolism of steroids (Sus scrofa)
Metabolism of steroid hormones (Sus scrofa)
Androgen biosynthesis (Sus scrofa)
CYP17A1 17-hydroxylates PREG (Sus scrofa)
PREG [cytosol]
Glucocorticoid biosynthesis (Sus scrofa)
CYP17A1 17-hydroxylates PREG (Sus scrofa)
PREG [cytosol]
Mineralocorticoid biosynthesis (Sus scrofa)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Sus scrofa)
PREG [cytosol]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase II - Conjugation of compounds (Xenopus tropicalis)
Cytosolic sulfonation of small molecules (Xenopus tropicalis)
SULTs transfer (SO4)2- group to PREG (Xenopus tropicalis)
PREG [cytosol]
Metabolism of lipids (Xenopus tropicalis)
Metabolism of steroids (Xenopus tropicalis)
Metabolism of steroid hormones (Xenopus tropicalis)
Androgen biosynthesis (Xenopus tropicalis)
CYP17A1 17-hydroxylates PREG (Xenopus tropicalis)
PREG [cytosol]
Glucocorticoid biosynthesis (Xenopus tropicalis)
CYP17A1 17-hydroxylates PREG (Xenopus tropicalis)
PREG [cytosol]
Mineralocorticoid biosynthesis (Xenopus tropicalis)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Xenopus tropicalis)
PREG [cytosol]
External Reference Information
External Reference
pregnenolone [ChEBI:16581]
Participates
as an input of
Defective CYP17A1 does not 17-hydroxylate PREG (Homo sapiens)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Drosophila melanogaster)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Gallus gallus)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Xenopus tropicalis)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Danio rerio)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Sus scrofa)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Bos taurus)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Canis familiaris)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Rattus norvegicus)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Mus musculus)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Homo sapiens)
CYP17A1 17-hydroxylates PREG (Gallus gallus)
CYP17A1 17-hydroxylates PREG (Xenopus tropicalis)
CYP17A1 17-hydroxylates PREG (Danio rerio)
CYP17A1 17-hydroxylates PREG (Sus scrofa)
CYP17A1 17-hydroxylates PREG (Bos taurus)
CYP17A1 17-hydroxylates PREG (Canis familiaris)
CYP17A1 17-hydroxylates PREG (Rattus norvegicus)
CYP17A1 17-hydroxylates PREG (Mus musculus)
CYP17A1 17-hydroxylates PREG (Homo sapiens)
SULTs transfer (SO4)2- group to PREG (Caenorhabditis elegans)
SULTs transfer (SO4)2- group to PREG (Drosophila melanogaster)
SULTs transfer (SO4)2- group to PREG (Gallus gallus)
SULTs transfer (SO4)2- group to PREG (Xenopus tropicalis)
SULTs transfer (SO4)2- group to PREG (Danio rerio)
SULTs transfer (SO4)2- group to PREG (Sus scrofa)
SULTs transfer (SO4)2- group to PREG (Bos taurus)
SULTs transfer (SO4)2- group to PREG (Canis familiaris)
SULTs transfer (SO4)2- group to PREG (Rattus norvegicus)
SULTs transfer (SO4)2- group to PREG (Mus musculus)
SULTs transfer (SO4)2- group to PREG (Homo sapiens)
as an output of
Pregnenolone translocates from the mitochondrial matrix to the cytosol (Homo sapiens)
Other forms of this molecule
PREG [mitochondrial matrix]
Cross References
COMPOUND
C01953
PubChem Substance
8143499
HMDB Metabolite
HMDB0000253
ZINC
000003861150
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