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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
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ANDST [cytosol]
Stable Identifier
R-ALL-193079
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
4-Androstene-3, 17-dione, androst-4-ene-3,17-dione
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Bos taurus)
Androgens binds AR (in the HSP90 chaperone complex) (Bos taurus)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Bos taurus)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Bos taurus)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Bos taurus)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Bos taurus)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Bos taurus)
Androgens [cytosol]
ANDST [cytosol]
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Cytochrome P450 - arranged by substrate type (Bos taurus)
Endogenous sterols (Bos taurus)
CYP19A1 hydroxylates ANDST to E1 (Bos taurus)
ANDST [cytosol]
Metabolism of lipids (Bos taurus)
Metabolism of steroids (Bos taurus)
Metabolism of steroid hormones (Bos taurus)
Androgen biosynthesis (Bos taurus)
CYP17A1 cleaves 17aHPROG to ANDST (Bos taurus)
ANDST [cytosol]
HSD17B3-like proteins reducde ANDST to TEST (Bos taurus)
ANDST [cytosol]
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Bos taurus)
ANDST [cytosol]
Estrogen biosynthesis (Bos taurus)
CYP19A1 hydroxylates ANDST to E1 (Bos taurus)
ANDST [cytosol]
Signal Transduction (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases activate PKNs (Bos taurus)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Bos taurus)
Phosphorylated PKN1 binds androgen receptor (AR) (Bos taurus)
AR:Androgens [cytosol] (Bos taurus)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen [cytosol] (Bos taurus)
AR:Androgens [cytosol] (Bos taurus)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Bos taurus)
p-T774-PKN1:AR:Androgen [cytosol] (Bos taurus)
AR:Androgens [cytosol] (Bos taurus)
Androgens [cytosol]
ANDST [cytosol]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase I - Functionalization of compounds (Caenorhabditis elegans)
Cytochrome P450 - arranged by substrate type (Caenorhabditis elegans)
Endogenous sterols (Caenorhabditis elegans)
CYP19A1 hydroxylates ANDST to E1 (Caenorhabditis elegans)
ANDST [cytosol]
Metabolism of lipids (Caenorhabditis elegans)
Metabolism of steroids (Caenorhabditis elegans)
Metabolism of steroid hormones (Caenorhabditis elegans)
Androgen biosynthesis (Caenorhabditis elegans)
HSD17B3-like proteins reducde ANDST to TEST (Caenorhabditis elegans)
ANDST [cytosol]
Estrogen biosynthesis (Caenorhabditis elegans)
CYP19A1 hydroxylates ANDST to E1 (Caenorhabditis elegans)
ANDST [cytosol]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Canis familiaris)
Androgens binds AR (in the HSP90 chaperone complex) (Canis familiaris)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Canis familiaris)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Canis familiaris)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Canis familiaris)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Canis familiaris)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Canis familiaris)
Androgens [cytosol]
ANDST [cytosol]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Cytochrome P450 - arranged by substrate type (Canis familiaris)
Endogenous sterols (Canis familiaris)
CYP19A1 hydroxylates ANDST to E1 (Canis familiaris)
ANDST [cytosol]
Metabolism of lipids (Canis familiaris)
Metabolism of steroids (Canis familiaris)
Metabolism of steroid hormones (Canis familiaris)
Androgen biosynthesis (Canis familiaris)
CYP17A1 cleaves 17aHPROG to ANDST (Canis familiaris)
ANDST [cytosol]
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Canis familiaris)
ANDST [cytosol]
Estrogen biosynthesis (Canis familiaris)
CYP19A1 hydroxylates ANDST to E1 (Canis familiaris)
ANDST [cytosol]
Signal Transduction (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases activate PKNs (Canis familiaris)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Canis familiaris)
Phosphorylated PKN1 binds androgen receptor (AR) (Canis familiaris)
AR:Androgens [cytosol] (Canis familiaris)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen [cytosol] (Canis familiaris)
AR:Androgens [cytosol] (Canis familiaris)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Canis familiaris)
p-T774-PKN1:AR:Androgen [cytosol] (Canis familiaris)
AR:Androgens [cytosol] (Canis familiaris)
Androgens [cytosol]
ANDST [cytosol]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Danio rerio)
Androgens binds AR (in the HSP90 chaperone complex) (Danio rerio)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Danio rerio)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Danio rerio)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Danio rerio)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Danio rerio)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Danio rerio)
Androgens [cytosol]
ANDST [cytosol]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
Cytochrome P450 - arranged by substrate type (Danio rerio)
Endogenous sterols (Danio rerio)
CYP19A1 hydroxylates ANDST to E1 (Danio rerio)
ANDST [cytosol]
Metabolism of lipids (Danio rerio)
Metabolism of steroids (Danio rerio)
Metabolism of steroid hormones (Danio rerio)
Androgen biosynthesis (Danio rerio)
CYP17A1 cleaves 17aHPROG to ANDST (Danio rerio)
ANDST [cytosol]
HSD17B3-like proteins reducde ANDST to TEST (Danio rerio)
ANDST [cytosol]
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Danio rerio)
ANDST [cytosol]
Estrogen biosynthesis (Danio rerio)
CYP19A1 hydroxylates ANDST to E1 (Danio rerio)
ANDST [cytosol]
Signal Transduction (Danio rerio)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
Signaling by Rho GTPases (Danio rerio)
RHO GTPase Effectors (Danio rerio)
RHO GTPases activate PKNs (Danio rerio)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Danio rerio)
Phosphorylated PKN1 binds androgen receptor (AR) (Danio rerio)
AR:Androgens [cytosol] (Danio rerio)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen [cytosol] (Danio rerio)
AR:Androgens [cytosol] (Danio rerio)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Danio rerio)
p-T774-PKN1:AR:Androgen [cytosol] (Danio rerio)
AR:Androgens [cytosol] (Danio rerio)
Androgens [cytosol]
ANDST [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of lipids (Dictyostelium discoideum)
Metabolism of steroids (Dictyostelium discoideum)
Metabolism of steroid hormones (Dictyostelium discoideum)
Androgen biosynthesis (Dictyostelium discoideum)
HSD17B3-like proteins reducde ANDST to TEST (Dictyostelium discoideum)
ANDST [cytosol]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Drosophila melanogaster)
Androgens binds AR (in the HSP90 chaperone complex) (Drosophila melanogaster)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Drosophila melanogaster)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Drosophila melanogaster)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Drosophila melanogaster)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Drosophila melanogaster)
Androgens [cytosol]
ANDST [cytosol]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase I - Functionalization of compounds (Drosophila melanogaster)
Cytochrome P450 - arranged by substrate type (Drosophila melanogaster)
Endogenous sterols (Drosophila melanogaster)
CYP19A1 hydroxylates ANDST to E1 (Drosophila melanogaster)
ANDST [cytosol]
Metabolism of lipids (Drosophila melanogaster)
Metabolism of steroids (Drosophila melanogaster)
Metabolism of steroid hormones (Drosophila melanogaster)
Androgen biosynthesis (Drosophila melanogaster)
HSD17B3-like proteins reducde ANDST to TEST (Drosophila melanogaster)
ANDST [cytosol]
Estrogen biosynthesis (Drosophila melanogaster)
CYP19A1 hydroxylates ANDST to E1 (Drosophila melanogaster)
ANDST [cytosol]
Signal Transduction (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases activate PKNs (Drosophila melanogaster)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Drosophila melanogaster)
Phosphorylated PKN1 binds androgen receptor (AR) (Drosophila melanogaster)
AR:Androgens [cytosol] (Drosophila melanogaster)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen [cytosol] (Drosophila melanogaster)
AR:Androgens [cytosol] (Drosophila melanogaster)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Drosophila melanogaster)
p-T774-PKN1:AR:Androgen [cytosol] (Drosophila melanogaster)
AR:Androgens [cytosol] (Drosophila melanogaster)
Androgens [cytosol]
ANDST [cytosol]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Gallus gallus)
Androgens binds AR (in the HSP90 chaperone complex) (Gallus gallus)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Gallus gallus)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Gallus gallus)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Gallus gallus)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Gallus gallus)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Gallus gallus)
Androgens [cytosol]
ANDST [cytosol]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
Cytochrome P450 - arranged by substrate type (Gallus gallus)
Endogenous sterols (Gallus gallus)
CYP19A1 hydroxylates ANDST to E1 (Gallus gallus)
ANDST [cytosol]
Metabolism of lipids (Gallus gallus)
Metabolism of steroids (Gallus gallus)
Metabolism of steroid hormones (Gallus gallus)
Androgen biosynthesis (Gallus gallus)
CYP17A1 cleaves 17aHPROG to ANDST (Gallus gallus)
ANDST [cytosol]
HSD17B3-like proteins reducde ANDST to TEST (Gallus gallus)
ANDST [cytosol]
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Gallus gallus)
ANDST [cytosol]
Estrogen biosynthesis (Gallus gallus)
CYP19A1 hydroxylates ANDST to E1 (Gallus gallus)
ANDST [cytosol]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Homo sapiens)
Androgens binds AR (in the HSP90 chaperone complex) (Homo sapiens)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Homo sapiens)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Homo sapiens)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Homo sapiens)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Homo sapiens)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Homo sapiens)
Androgens [cytosol]
ANDST [cytosol]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Metabolic disorders of biological oxidation enzymes (Homo sapiens)
Defective CYP19A1 causes AEXS (Homo sapiens)
Defective CYP19A1 does not convert ANDST to E1 (Homo sapiens)
ANDST [cytosol]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Endogenous sterols (Homo sapiens)
CYP19A1 hydroxylates ANDST to E1 (Homo sapiens)
ANDST [cytosol]
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Metabolism of steroid hormones (Homo sapiens)
Androgen biosynthesis (Homo sapiens)
CYP17A1 cleaves 17aHPROG to ANDST (Homo sapiens)
ANDST [cytosol]
HSD17B3-like proteins reducde ANDST to TEST (Homo sapiens)
ANDST [cytosol]
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Homo sapiens)
ANDST [cytosol]
Estrogen biosynthesis (Homo sapiens)
CYP19A1 hydroxylates ANDST to E1 (Homo sapiens)
ANDST [cytosol]
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases activate PKNs (Homo sapiens)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Homo sapiens)
Phosphorylated PKN1 binds androgen receptor (AR) (Homo sapiens)
AR:Androgens [cytosol] (Homo sapiens)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen [cytosol] (Homo sapiens)
AR:Androgens [cytosol] (Homo sapiens)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Homo sapiens)
p-T774-PKN1:AR:Androgen [cytosol] (Homo sapiens)
AR:Androgens [cytosol] (Homo sapiens)
Androgens [cytosol]
ANDST [cytosol]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Mus musculus)
Androgens binds AR (in the HSP90 chaperone complex) (Mus musculus)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Mus musculus)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Mus musculus)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Mus musculus)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Mus musculus)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Mus musculus)
Androgens [cytosol]
ANDST [cytosol]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Endogenous sterols (Mus musculus)
CYP19A1 hydroxylates ANDST to E1 (Mus musculus)
ANDST [cytosol]
Metabolism of lipids (Mus musculus)
Metabolism of steroids (Mus musculus)
Metabolism of steroid hormones (Mus musculus)
Androgen biosynthesis (Mus musculus)
CYP17A1 cleaves 17aHPROG to ANDST (Mus musculus)
ANDST [cytosol]
HSD17B3-like proteins reducde ANDST to TEST (Mus musculus)
ANDST [cytosol]
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Mus musculus)
ANDST [cytosol]
Estrogen biosynthesis (Mus musculus)
CYP19A1 hydroxylates ANDST to E1 (Mus musculus)
ANDST [cytosol]
Signal Transduction (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases activate PKNs (Mus musculus)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Mus musculus)
Phosphorylated PKN1 binds androgen receptor (AR) (Mus musculus)
AR:Androgens [cytosol] (Mus musculus)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen [cytosol] (Mus musculus)
AR:Androgens [cytosol] (Mus musculus)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Mus musculus)
p-T774-PKN1:AR:Androgen [cytosol] (Mus musculus)
AR:Androgens [cytosol] (Mus musculus)
Androgens [cytosol]
ANDST [cytosol]
Cellular responses to stimuli (Plasmodium falciparum)
Cellular responses to stress (Plasmodium falciparum)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Plasmodium falciparum)
Androgens binds AR (in the HSP90 chaperone complex) (Plasmodium falciparum)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Plasmodium falciparum)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Plasmodium falciparum)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Plasmodium falciparum)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Plasmodium falciparum)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Plasmodium falciparum)
Androgens [cytosol]
ANDST [cytosol]
Metabolism (Plasmodium falciparum)
Metabolism of lipids (Plasmodium falciparum)
Metabolism of steroids (Plasmodium falciparum)
Metabolism of steroid hormones (Plasmodium falciparum)
Androgen biosynthesis (Plasmodium falciparum)
HSD17B3-like proteins reducde ANDST to TEST (Plasmodium falciparum)
ANDST [cytosol]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Rattus norvegicus)
Androgens binds AR (in the HSP90 chaperone complex) (Rattus norvegicus)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Rattus norvegicus)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Rattus norvegicus)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Rattus norvegicus)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Rattus norvegicus)
Androgens [cytosol]
ANDST [cytosol]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Cytochrome P450 - arranged by substrate type (Rattus norvegicus)
Endogenous sterols (Rattus norvegicus)
CYP19A1 hydroxylates ANDST to E1 (Rattus norvegicus)
ANDST [cytosol]
Metabolism of lipids (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Metabolism of steroid hormones (Rattus norvegicus)
Androgen biosynthesis (Rattus norvegicus)
CYP17A1 cleaves 17aHPROG to ANDST (Rattus norvegicus)
ANDST [cytosol]
HSD17B3-like proteins reducde ANDST to TEST (Rattus norvegicus)
ANDST [cytosol]
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Rattus norvegicus)
ANDST [cytosol]
Estrogen biosynthesis (Rattus norvegicus)
CYP19A1 hydroxylates ANDST to E1 (Rattus norvegicus)
ANDST [cytosol]
Signal Transduction (Rattus norvegicus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase Effectors (Rattus norvegicus)
RHO GTPases activate PKNs (Rattus norvegicus)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Rattus norvegicus)
Phosphorylated PKN1 binds androgen receptor (AR) (Rattus norvegicus)
AR:Androgens [cytosol] (Rattus norvegicus)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen [cytosol] (Rattus norvegicus)
AR:Androgens [cytosol] (Rattus norvegicus)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [cytosol] (Rattus norvegicus)
AR:Androgens [cytosol] (Rattus norvegicus)
Androgens [cytosol]
ANDST [cytosol]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Sus scrofa)
Androgens binds AR (in the HSP90 chaperone complex) (Sus scrofa)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Sus scrofa)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Sus scrofa)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Sus scrofa)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Sus scrofa)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Sus scrofa)
Androgens [cytosol]
ANDST [cytosol]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Cytochrome P450 - arranged by substrate type (Sus scrofa)
Endogenous sterols (Sus scrofa)
CYP19A1 hydroxylates ANDST to E1 (Sus scrofa)
ANDST [cytosol]
Metabolism of lipids (Sus scrofa)
Metabolism of steroids (Sus scrofa)
Metabolism of steroid hormones (Sus scrofa)
Androgen biosynthesis (Sus scrofa)
CYP17A1 cleaves 17aHPROG to ANDST (Sus scrofa)
ANDST [cytosol]
HSD17B3-like proteins reducde ANDST to TEST (Sus scrofa)
ANDST [cytosol]
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Sus scrofa)
ANDST [cytosol]
Estrogen biosynthesis (Sus scrofa)
CYP19A1 hydroxylates ANDST to E1 (Sus scrofa)
ANDST [cytosol]
Signal Transduction (Sus scrofa)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase Effectors (Sus scrofa)
RHO GTPases activate PKNs (Sus scrofa)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Sus scrofa)
Phosphorylated PKN1 binds androgen receptor (AR) (Sus scrofa)
AR:Androgens [cytosol] (Sus scrofa)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen [cytosol] (Sus scrofa)
AR:Androgens [cytosol] (Sus scrofa)
Androgens [cytosol]
ANDST [cytosol]
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Sus scrofa)
p-T774-PKN1:AR:Androgen [cytosol] (Sus scrofa)
AR:Androgens [cytosol] (Sus scrofa)
Androgens [cytosol]
ANDST [cytosol]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Xenopus tropicalis)
Androgens binds AR (in the HSP90 chaperone complex) (Xenopus tropicalis)
Androgens [cytosol]
ANDST [cytosol]
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Xenopus tropicalis)
Androgens [cytosol]
ANDST [cytosol]
AR:Androgens [cytosol] (Xenopus tropicalis)
Androgens [cytosol]
ANDST [cytosol]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase I - Functionalization of compounds (Xenopus tropicalis)
Cytochrome P450 - arranged by substrate type (Xenopus tropicalis)
Endogenous sterols (Xenopus tropicalis)
CYP19A1 hydroxylates ANDST to E1 (Xenopus tropicalis)
ANDST [cytosol]
Metabolism of lipids (Xenopus tropicalis)
Metabolism of steroids (Xenopus tropicalis)
Metabolism of steroid hormones (Xenopus tropicalis)
Androgen biosynthesis (Xenopus tropicalis)
CYP17A1 cleaves 17aHPROG to ANDST (Xenopus tropicalis)
ANDST [cytosol]
Estrogen biosynthesis (Xenopus tropicalis)
CYP19A1 hydroxylates ANDST to E1 (Xenopus tropicalis)
ANDST [cytosol]
External Reference Information
External Reference
androst-4-ene-3,17-dione [ChEBI:16422]
Participates
as an input of
Defective CYP19A1 does not convert ANDST to E1 (Homo sapiens)
CYP19A1 hydroxylates ANDST to E1 (Caenorhabditis elegans)
CYP19A1 hydroxylates ANDST to E1 (Drosophila melanogaster)
CYP19A1 hydroxylates ANDST to E1 (Gallus gallus)
CYP19A1 hydroxylates ANDST to E1 (Xenopus tropicalis)
CYP19A1 hydroxylates ANDST to E1 (Danio rerio)
CYP19A1 hydroxylates ANDST to E1 (Sus scrofa)
CYP19A1 hydroxylates ANDST to E1 (Bos taurus)
CYP19A1 hydroxylates ANDST to E1 (Canis familiaris)
CYP19A1 hydroxylates ANDST to E1 (Rattus norvegicus)
CYP19A1 hydroxylates ANDST to E1 (Mus musculus)
CYP19A1 hydroxylates ANDST to E1 (Homo sapiens)
HSD17B3-like proteins reducde ANDST to TEST (Plasmodium falciparum)
HSD17B3-like proteins reducde ANDST to TEST (Dictyostelium discoideum)
HSD17B3-like proteins reducde ANDST to TEST (Caenorhabditis elegans)
HSD17B3-like proteins reducde ANDST to TEST (Drosophila melanogaster)
HSD17B3-like proteins reducde ANDST to TEST (Gallus gallus)
HSD17B3-like proteins reducde ANDST to TEST (Danio rerio)
HSD17B3-like proteins reducde ANDST to TEST (Sus scrofa)
HSD17B3-like proteins reducde ANDST to TEST (Bos taurus)
HSD17B3-like proteins reducde ANDST to TEST (Rattus norvegicus)
HSD17B3-like proteins reducde ANDST to TEST (Mus musculus)
HSD17B3-like proteins reducde ANDST to TEST (Homo sapiens)
as an output of
CYP17A1 cleaves 17aHPROG to ANDST (Gallus gallus)
CYP17A1 cleaves 17aHPROG to ANDST (Xenopus tropicalis)
CYP17A1 cleaves 17aHPROG to ANDST (Danio rerio)
CYP17A1 cleaves 17aHPROG to ANDST (Sus scrofa)
CYP17A1 cleaves 17aHPROG to ANDST (Bos taurus)
CYP17A1 cleaves 17aHPROG to ANDST (Canis familiaris)
CYP17A1 cleaves 17aHPROG to ANDST (Rattus norvegicus)
CYP17A1 cleaves 17aHPROG to ANDST (Mus musculus)
CYP17A1 cleaves 17aHPROG to ANDST (Homo sapiens)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Gallus gallus)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Danio rerio)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Sus scrofa)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Bos taurus)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Canis familiaris)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Rattus norvegicus)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Mus musculus)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Homo sapiens)
as a member of
Androgens [cytosol]
Other forms of this molecule
androst-4-en-3,17-dione [nucleoplasm]
Cross References
Guide to Pharmacology - Ligands
2860
COMPOUND
C00280
HMDB Metabolite
HMDB0000053
ZINC
000004428526
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