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About
What is Reactome ?
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Fru [extracellular region]
Stable Identifier
R-ALL-189049
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
Levulose, D-fructose, Fruit sugar, D-Arabino-hexulose
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Digestion and absorption (Bos taurus)
Digestion (Bos taurus)
Digestion of dietary carbohydrate (Bos taurus)
sucrose + H2O => glucose + fructose (Bos taurus)
Fru [extracellular region]
Intestinal absorption (Bos taurus)
Intestinal hexose absorption (Bos taurus)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Bos taurus)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
SLC2A5 transports fructose from extracellular region to cytosol (Bos taurus)
Fru [extracellular region]
Sensory Perception (Bos taurus)
Sensory perception of taste (Bos taurus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Bos taurus)
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Bos taurus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (i) signalling events (Bos taurus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
GPCR ligand binding (Bos taurus)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Bos taurus)
T1R2/T1R3 dimer is a sweet taste receptor (Bos taurus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Bos taurus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Cellular hexose transport (Bos taurus)
GLUT7 and GLUT11 transport glucose and fructose (Bos taurus)
hexoses transported by GLUT7/11 [extracellular region]
Fru [extracellular region]
SLC2A9 transports Fru, Glc, urate (Bos taurus)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Bos taurus)
Fru, Man [extracellular region]
Fru [extracellular region]
Digestion and absorption (Caenorhabditis elegans)
Digestion (Caenorhabditis elegans)
Digestion of dietary carbohydrate (Caenorhabditis elegans)
sucrose + H2O => glucose + fructose (Caenorhabditis elegans)
Fru [extracellular region]
Intestinal absorption (Caenorhabditis elegans)
Intestinal hexose absorption (Caenorhabditis elegans)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Caenorhabditis elegans)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
SLC2A5 transports fructose from extracellular region to cytosol (Caenorhabditis elegans)
Fru [extracellular region]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Cellular hexose transport (Caenorhabditis elegans)
GLUT7 and GLUT11 transport glucose and fructose (Caenorhabditis elegans)
hexoses transported by GLUT7/11 [extracellular region]
Fru [extracellular region]
SLC2A9 transports Fru, Glc, urate (Caenorhabditis elegans)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
Digestion and absorption (Canis familiaris)
Digestion (Canis familiaris)
Digestion of dietary carbohydrate (Canis familiaris)
sucrose + H2O => glucose + fructose (Canis familiaris)
Fru [extracellular region]
Intestinal absorption (Canis familiaris)
Intestinal hexose absorption (Canis familiaris)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Canis familiaris)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
SLC2A5 transports fructose from extracellular region to cytosol (Canis familiaris)
Fru [extracellular region]
Sensory Perception (Canis familiaris)
Sensory perception of taste (Canis familiaris)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Canis familiaris)
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Canis familiaris)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Canis familiaris)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Cellular hexose transport (Canis familiaris)
GLUT7 and GLUT11 transport glucose and fructose (Canis familiaris)
hexoses transported by GLUT7/11 [extracellular region]
Fru [extracellular region]
SLC2A9 transports Fru, Glc, urate (Canis familiaris)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Canis familiaris)
Fru, Man [extracellular region]
Fru [extracellular region]
Digestion and absorption (Danio rerio)
Intestinal absorption (Danio rerio)
Intestinal hexose absorption (Danio rerio)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Danio rerio)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
Sensory Perception (Danio rerio)
Sensory perception of taste (Danio rerio)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Danio rerio)
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Danio rerio)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Danio rerio)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Signal Transduction (Danio rerio)
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (i) signalling events (Danio rerio)
Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Danio rerio)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Danio rerio)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
GPCR ligand binding (Danio rerio)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Danio rerio)
T1R2/T1R3 dimer is a sweet taste receptor (Danio rerio)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Danio rerio)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Digestion and absorption (Dictyostelium discoideum)
Digestion (Dictyostelium discoideum)
Digestion of dietary carbohydrate (Dictyostelium discoideum)
sucrose + H2O => glucose + fructose (Dictyostelium discoideum)
Fru [extracellular region]
Intestinal absorption (Dictyostelium discoideum)
Intestinal hexose absorption (Dictyostelium discoideum)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Dictyostelium discoideum)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
SLC2A5 transports fructose from extracellular region to cytosol (Dictyostelium discoideum)
Fru [extracellular region]
Transport of small molecules (Dictyostelium discoideum)
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Cellular hexose transport (Dictyostelium discoideum)
GLUT7 and GLUT11 transport glucose and fructose (Dictyostelium discoideum)
hexoses transported by GLUT7/11 [extracellular region]
Fru [extracellular region]
SLC2A9 transports Fru, Glc, urate (Dictyostelium discoideum)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
Digestion and absorption (Drosophila melanogaster)
Intestinal absorption (Drosophila melanogaster)
Intestinal hexose absorption (Drosophila melanogaster)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Drosophila melanogaster)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
SLC2A5 transports fructose from extracellular region to cytosol (Drosophila melanogaster)
Fru [extracellular region]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Cellular hexose transport (Drosophila melanogaster)
GLUT7 and GLUT11 transport glucose and fructose (Drosophila melanogaster)
hexoses transported by GLUT7/11 [extracellular region]
Fru [extracellular region]
SLC2A9 transports Fru, Glc, urate (Drosophila melanogaster)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
Digestion and absorption (Gallus gallus)
Digestion (Gallus gallus)
Digestion of dietary carbohydrate (Gallus gallus)
sucrose + H2O => glucose + fructose (Gallus gallus)
Fru [extracellular region]
Intestinal absorption (Gallus gallus)
Intestinal hexose absorption (Gallus gallus)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Gallus gallus)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
SLC2A5 transports fructose from extracellular region to cytosol (Gallus gallus)
Fru [extracellular region]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Cellular hexose transport (Gallus gallus)
GLUT7 and GLUT11 transport glucose and fructose (Gallus gallus)
hexoses transported by GLUT7/11 [extracellular region]
Fru [extracellular region]
SLC2A9 transports Fru, Glc, urate (Gallus gallus)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Gallus gallus)
Fru, Man [extracellular region]
Fru [extracellular region]
Digestion and absorption (Homo sapiens)
Digestion (Homo sapiens)
Digestion of dietary carbohydrate (Homo sapiens)
sucrose + H2O => glucose + fructose (Homo sapiens)
Fru [extracellular region]
Intestinal absorption (Homo sapiens)
Intestinal hexose absorption (Homo sapiens)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Homo sapiens)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
SLC2A5 transports fructose from extracellular region to cytosol (Homo sapiens)
Fru [extracellular region]
Disease (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
SLC transporter disorders (Homo sapiens)
Defective SLC2A9 causes hypouricemia renal 2 (RHUC2) (Homo sapiens)
Defective SLC2A9 does not transport Fru, Glc, urate (Homo sapiens)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
Sensory Perception (Homo sapiens)
Sensory perception of taste (Homo sapiens)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Homo sapiens)
GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GTP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 (Homo sapiens)
TAS1R2:TAS1R3:Sweet compound:GNAT3:GTP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
GPCR ligand binding (Homo sapiens)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Homo sapiens)
T1R2/T1R3 dimer is a sweet taste receptor (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Cellular hexose transport (Homo sapiens)
GLUT7 and GLUT11 transport glucose and fructose (Homo sapiens)
hexoses transported by GLUT7/11 [extracellular region]
Fru [extracellular region]
SLC2A9 transports Fru, Glc, urate (Homo sapiens)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Homo sapiens)
Fru, Man [extracellular region]
Fru [extracellular region]
Digestion and absorption (Mus musculus)
Digestion (Mus musculus)
Digestion of dietary carbohydrate (Mus musculus)
sucrose + H2O => glucose + fructose (Mus musculus)
Fru [extracellular region]
Intestinal absorption (Mus musculus)
Intestinal hexose absorption (Mus musculus)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Mus musculus)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
SLC2A5 transports fructose from extracellular region to cytosol (Mus musculus)
Fru [extracellular region]
Sensory Perception (Mus musculus)
Sensory perception of taste (Mus musculus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Mus musculus)
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Mus musculus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (i) signalling events (Mus musculus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
GPCR ligand binding (Mus musculus)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Mus musculus)
T1R2/T1R3 dimer is a sweet taste receptor (Mus musculus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Cellular hexose transport (Mus musculus)
GLUT7 and GLUT11 transport glucose and fructose (Mus musculus)
hexoses transported by GLUT7/11 [extracellular region]
Fru [extracellular region]
SLC2A9 transports Fru, Glc, urate (Mus musculus)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Mus musculus)
Fru, Man [extracellular region]
Fru [extracellular region]
Digestion and absorption (Plasmodium falciparum)
Intestinal absorption (Plasmodium falciparum)
Intestinal hexose absorption (Plasmodium falciparum)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Plasmodium falciparum)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
SLC2A5 transports fructose from extracellular region to cytosol (Plasmodium falciparum)
Fru [extracellular region]
Transport of small molecules (Plasmodium falciparum)
SLC-mediated transmembrane transport (Plasmodium falciparum)
Cellular hexose transport (Plasmodium falciparum)
GLUT7 and GLUT11 transport glucose and fructose (Plasmodium falciparum)
hexoses transported by GLUT7/11 [extracellular region]
Fru [extracellular region]
SLC2A9 transports Fru, Glc, urate (Plasmodium falciparum)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
Digestion and absorption (Rattus norvegicus)
Digestion (Rattus norvegicus)
Digestion of dietary carbohydrate (Rattus norvegicus)
sucrose + H2O => glucose + fructose (Rattus norvegicus)
Fru [extracellular region]
Intestinal absorption (Rattus norvegicus)
Intestinal hexose absorption (Rattus norvegicus)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Rattus norvegicus)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
SLC2A5 transports fructose from extracellular region to cytosol (Rattus norvegicus)
Fru [extracellular region]
Sensory Perception (Rattus norvegicus)
Sensory perception of taste (Rattus norvegicus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Rattus norvegicus)
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Rattus norvegicus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Rattus norvegicus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Rattus norvegicus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Signal Transduction (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (i) signalling events (Rattus norvegicus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Rattus norvegicus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Rattus norvegicus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
GPCR ligand binding (Rattus norvegicus)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Rattus norvegicus)
T1R2/T1R3 dimer is a sweet taste receptor (Rattus norvegicus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Rattus norvegicus)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Cellular hexose transport (Rattus norvegicus)
GLUT7 and GLUT11 transport glucose and fructose (Rattus norvegicus)
hexoses transported by GLUT7/11 [extracellular region]
Fru [extracellular region]
SLC2A9 transports Fru, Glc, urate (Rattus norvegicus)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Rattus norvegicus)
Fru, Man [extracellular region]
Fru [extracellular region]
Digestion and absorption (Saccharomyces cerevisiae)
Intestinal absorption (Saccharomyces cerevisiae)
Intestinal hexose absorption (Saccharomyces cerevisiae)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Saccharomyces cerevisiae)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
SLC2A5 transports fructose from extracellular region to cytosol (Saccharomyces cerevisiae)
Fru [extracellular region]
Transport of small molecules (Saccharomyces cerevisiae)
SLC-mediated transmembrane transport (Saccharomyces cerevisiae)
Cellular hexose transport (Saccharomyces cerevisiae)
GLUT7 and GLUT11 transport glucose and fructose (Saccharomyces cerevisiae)
hexoses transported by GLUT7/11 [extracellular region]
Fru [extracellular region]
SLC2A9 transports Fru, Glc, urate (Saccharomyces cerevisiae)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
Digestion and absorption (Schizosaccharomyces pombe)
Digestion (Schizosaccharomyces pombe)
Digestion of dietary carbohydrate (Schizosaccharomyces pombe)
sucrose + H2O => glucose + fructose (Schizosaccharomyces pombe)
Fru [extracellular region]
Digestion and absorption (Sus scrofa)
Digestion (Sus scrofa)
Digestion of dietary carbohydrate (Sus scrofa)
sucrose + H2O => glucose + fructose (Sus scrofa)
Fru [extracellular region]
Intestinal absorption (Sus scrofa)
Intestinal hexose absorption (Sus scrofa)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Sus scrofa)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
SLC2A5 transports fructose from extracellular region to cytosol (Sus scrofa)
Fru [extracellular region]
Sensory Perception (Sus scrofa)
Sensory perception of taste (Sus scrofa)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Sus scrofa)
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Sus scrofa)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (i) signalling events (Sus scrofa)
Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
GPCR ligand binding (Sus scrofa)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Sus scrofa)
T1R2/T1R3 dimer is a sweet taste receptor (Sus scrofa)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
Sweet taste compounds [extracellular region]
Fru [extracellular region]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Cellular hexose transport (Sus scrofa)
GLUT7 and GLUT11 transport glucose and fructose (Sus scrofa)
hexoses transported by GLUT7/11 [extracellular region]
Fru [extracellular region]
SLC2A9 transports Fru, Glc, urate (Sus scrofa)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Sus scrofa)
Fru, Man [extracellular region]
Fru [extracellular region]
Digestion and absorption (Xenopus tropicalis)
Intestinal absorption (Xenopus tropicalis)
Intestinal hexose absorption (Xenopus tropicalis)
SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Xenopus tropicalis)
Fru, Gal, Glc [extracellular region]
Fru [extracellular region]
SLC2A5 transports fructose from extracellular region to cytosol (Xenopus tropicalis)
Fru [extracellular region]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Cellular hexose transport (Xenopus tropicalis)
GLUT7 and GLUT11 transport glucose and fructose (Xenopus tropicalis)
hexoses transported by GLUT7/11 [extracellular region]
Fru [extracellular region]
SLC2A9 transports Fru, Glc, urate (Xenopus tropicalis)
Fru,Glc,urate [extracellular region]
Fru [extracellular region]
SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Xenopus tropicalis)
Fru, Man [extracellular region]
Fru [extracellular region]
External Reference Information
External Reference
D-fructose [ChEBI:15824]
Participates
as a member of
Fru, Gal, Glc [extracellular region]
Fru, Man [extracellular region]
hexoses transported by GLUT7/11 [extracellular region]
Fru,Glc,urate [extracellular region]
Sweet taste compounds [extracellular region]
as an input of
SLC2A5 transports fructose from extracellular region to cytosol (Plasmodium falciparum)
SLC2A5 transports fructose from extracellular region to cytosol (Saccharomyces cerevisiae)
SLC2A5 transports fructose from extracellular region to cytosol (Dictyostelium discoideum)
SLC2A5 transports fructose from extracellular region to cytosol (Caenorhabditis elegans)
SLC2A5 transports fructose from extracellular region to cytosol (Drosophila melanogaster)
SLC2A5 transports fructose from extracellular region to cytosol (Gallus gallus)
SLC2A5 transports fructose from extracellular region to cytosol (Xenopus tropicalis)
SLC2A5 transports fructose from extracellular region to cytosol (Sus scrofa)
SLC2A5 transports fructose from extracellular region to cytosol (Bos taurus)
SLC2A5 transports fructose from extracellular region to cytosol (Canis familiaris)
SLC2A5 transports fructose from extracellular region to cytosol (Rattus norvegicus)
SLC2A5 transports fructose from extracellular region to cytosol (Mus musculus)
SLC2A5 transports fructose from extracellular region to cytosol (Homo sapiens)
as an output of
sucrose + H2O => glucose + fructose (Schizosaccharomyces pombe)
sucrose + H2O => glucose + fructose (Dictyostelium discoideum)
sucrose + H2O => glucose + fructose (Caenorhabditis elegans)
sucrose + H2O => glucose + fructose (Gallus gallus)
sucrose + H2O => glucose + fructose (Sus scrofa)
sucrose + H2O => glucose + fructose (Bos taurus)
sucrose + H2O => glucose + fructose (Canis familiaris)
sucrose + H2O => glucose + fructose (Rattus norvegicus)
sucrose + H2O => glucose + fructose (Mus musculus)
sucrose + H2O => glucose + fructose (Homo sapiens)
Other forms of this molecule
Fru [cytosol]
Cross References
Guide to Pharmacology - Ligands
4654
COMPOUND
C00095
,
C10906
PubChem Substance
8145406
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