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What is Reactome ?
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Table of Contents
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Antigen [plasma membrane]
Stable Identifier
R-ALL-173548
Type
OtherEntity
Compartment
plasma membrane
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Bos taurus)
Expression of peptide bound class I MHC on cell surface (Bos taurus)
Antigen peptide bound class I MHC [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen processing-Cross presentation (Bos taurus)
ER-Phagosome pathway (Bos taurus)
Export of peptide loaded MHC class I complex to PM (Bos taurus)
Antigen peptide bound class I MHC [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Endosomal/Vacuolar pathway (Bos taurus)
Translocation of peptide bound MHC class I complex to cell surface (Bos taurus)
Antigen peptide bound class I MHC [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Costimulation by the CD28 family (Bos taurus)
PD-1 signaling (Bos taurus)
Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Bos taurus)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Bos taurus)
C3d-complexed antigen binds to complement receptor (Bos taurus)
C3d complexed with antigen [extracellular region] (Bos taurus)
Antigen [plasma membrane]
Complex of CD19, CD81, CD225 and CD21 with C3d-bound Antigen [plasma membrane] (Bos taurus)
C3d complexed with antigen [extracellular region] (Bos taurus)
Antigen [plasma membrane]
TCR complex interacts with peptide antigen-presenting MHC Class I (Bos taurus)
Antigen peptide bound class I MHC [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
TCR interacting with antigen-bearing MHC Class I [plasma membrane] (Bos taurus)
Antigen peptide bound class I MHC [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Signaling by the B Cell Receptor (BCR) (Bos taurus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Bos taurus)
BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Bos taurus)
BLNK (SLP-65) Signalosome [plasma membrane] (Bos taurus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Bos taurus)
Antigen:p-BCR:p-SYK [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
BTK binds BTK inhibitors (Bos taurus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Bos taurus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Bos taurus)
Antigen:p-BCR:p-SYK [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
BTK:BTK inhibitors [plasma membrane] (Bos taurus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Bos taurus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Bos taurus)
Antigen:p-BCR:p-SYK [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 (Bos taurus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Bos taurus)
Antigen:p-BCR:p-SYK [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Bos taurus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Bos taurus)
Antigen:p-BCR:p-SYK [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
SYK autophosphorylates at the activated BCR (Bos taurus)
Antigen:p-BCR:SYK [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Bos taurus)
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
SYK binds the activated BCR (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen:p-BCR:SYK [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
p-6Y-SYK phosphorylates BLNK (SLP65) (Bos taurus)
Antigen:p-BCR:p-SYK [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Bos taurus)
Antigen:p-BCR:p-SYK [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
CD22 mediated BCR regulation (Bos taurus)
CD22 binds B-cell receptor (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
CD22:Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
LYN phosphorylates CD22 (Bos taurus)
CD22:Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
SHP1 binds p-CD22 (Bos taurus)
PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Bos taurus)
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen:p-BCR [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
TCR signaling (Bos taurus)
Downstream TCR signaling (Bos taurus)
Change of PKC theta conformation (Bos taurus)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Generation of second messenger molecules (Bos taurus)
Phosphorylation of PLC-gamma1 (Bos taurus)
ZAP-70 and ITK tyrosine kinases [plasma membrane] (Bos taurus)
Activated ZAP-70 [plasma membrane] (Bos taurus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Phosphorylation of SLP-76 (Bos taurus)
Activated ZAP-70 [plasma membrane] (Bos taurus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Phosphorylation of TBSMs in LAT (Bos taurus)
Activated ZAP-70 [plasma membrane] (Bos taurus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Phosphorylation of CD3 and TCR zeta chains (Bos taurus)
Activation of Lck (Bos taurus)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Dephosphorylation of Lck-pY505 by CD45 (Bos taurus)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Inactivation of LCK by PTPN22 (Bos taurus)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Inactivation of Lck by Csk (Bos taurus)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Phosphorylation of ITAM motifs in CD3 complexes (Bos taurus)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Translocation of ZAP-70 to Immunological synapse (Bos taurus)
Activation of ZAP-70 (Bos taurus)
Activated ZAP-70 [plasma membrane] (Bos taurus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Bos taurus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
PTPN22 dephosphorylates ZAP70 (Bos taurus)
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Bos taurus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Bos taurus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Phosphorylation of ZAP-70 by Lck (Bos taurus)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Bos taurus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Bos taurus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Recruitment of ZAP-70 to phosphorylated ITAMs (Bos taurus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Bos taurus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Bos taurus)
MHC Class II bearing antigen peptide [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Innate Immune System (Bos taurus)
Complement cascade (Bos taurus)
Initial triggering of complement (Bos taurus)
Conversion of C2 into C2a and C2b (Bos taurus)
C4 activators [plasma membrane] (Bos taurus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Conversion of C4 into C4a and C4b (Bos taurus)
C4 activators [plasma membrane] (Bos taurus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Creation of C4 and C2 activators (Bos taurus)
Classical antibody-mediated complement activation (Bos taurus)
Activation of C1r (Bos taurus)
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xC1R:2xC1S [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Activation of C1s (Bos taurus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Regulation of Complement cascade (Bos taurus)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Bos taurus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Bos taurus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
C1-Inh binds and inactivates C1r, C1s (Bos taurus)
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Bos taurus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Fcgamma receptor (FCGR) dependent phagocytosis (Bos taurus)
FCGR activation (Bos taurus)
Cross-linking of FCGRIA with IgG-coated Ag (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
IgG-Ag:FCGRIA:CD3G homodimer [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Cross-linking of FCGRIIA with IgG-coated Ag (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
IgG-Ag:FCGRIIA [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Regulation of actin dynamics for phagocytic cup formation (Bos taurus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Bos taurus)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Activation of RAC1 by VAV (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Phosphorylation of VAV (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Bos taurus)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Recruitment of VAV1 to p-6Y-SYK (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Role of phospholipids in phagocytosis (Bos taurus)
PI3K binds to p-6Y-SYK (Bos taurus)
PI3K:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
PI3K:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Phosphorylation and activation of PLCG (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Recruitment of PLCgamma to membrane (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Release of PLCG from FCGR (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Bos taurus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Bos taurus)
Antigen:IgG [plasma membrane] (Bos taurus)
Antigen [plasma membrane]
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Class I MHC mediated antigen processing & presentation (Canis familiaris)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Canis familiaris)
Expression of peptide bound class I MHC on cell surface (Canis familiaris)
Antigen peptide bound class I MHC [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen processing-Cross presentation (Canis familiaris)
ER-Phagosome pathway (Canis familiaris)
Export of peptide loaded MHC class I complex to PM (Canis familiaris)
Antigen peptide bound class I MHC [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Endosomal/Vacuolar pathway (Canis familiaris)
Translocation of peptide bound MHC class I complex to cell surface (Canis familiaris)
Antigen peptide bound class I MHC [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Costimulation by the CD28 family (Canis familiaris)
PD-1 signaling (Canis familiaris)
Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Canis familiaris)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Canis familiaris)
C3d-complexed antigen binds to complement receptor (Canis familiaris)
C3d complexed with antigen [extracellular region] (Canis familiaris)
Antigen [plasma membrane]
Complex of CD19, CD81, CD225 and CD21 with C3d-bound Antigen [plasma membrane] (Canis familiaris)
C3d complexed with antigen [extracellular region] (Canis familiaris)
Antigen [plasma membrane]
Fc gamma receptors interact with antigen-bound IgG (Canis familiaris)
Antigen-bound Ig G Antibody [extracellular region] (Canis familiaris)
Antigen [plasma membrane]
Antigen-bound antibody bound to lymphoid Fc gamma receptors [plasma membrane] (Canis familiaris)
Antigen-bound Ig G Antibody [extracellular region] (Canis familiaris)
Antigen [plasma membrane]
TCR complex interacts with peptide antigen-presenting MHC Class I (Canis familiaris)
Antigen peptide bound class I MHC [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
TCR interacting with antigen-bearing MHC Class I [plasma membrane] (Canis familiaris)
Antigen peptide bound class I MHC [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Signaling by the B Cell Receptor (BCR) (Canis familiaris)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Canis familiaris)
BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Canis familiaris)
BLNK (SLP-65) Signalosome [plasma membrane] (Canis familiaris)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
BTK binds BTK inhibitors (Canis familiaris)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Canis familiaris)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
BTK:BTK inhibitors [plasma membrane] (Canis familiaris)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Canis familiaris)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 (Canis familiaris)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Canis familiaris)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
SYK autophosphorylates at the activated BCR (Canis familiaris)
Antigen:p-BCR:SYK [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
SYK binds the activated BCR (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen:p-BCR:SYK [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
p-6Y-SYK phosphorylates BLNK (SLP65) (Canis familiaris)
Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
CD22 mediated BCR regulation (Canis familiaris)
CD22 binds B-cell receptor (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
LYN phosphorylates CD22 (Canis familiaris)
CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
SHP1 binds p-CD22 (Canis familiaris)
PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen:p-BCR [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
TCR signaling (Canis familiaris)
Downstream TCR signaling (Canis familiaris)
Change of PKC theta conformation (Canis familiaris)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Generation of second messenger molecules (Canis familiaris)
Phosphorylation of PLC-gamma1 (Canis familiaris)
ZAP-70 and ITK tyrosine kinases [plasma membrane] (Canis familiaris)
Activated ZAP-70 [plasma membrane] (Canis familiaris)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Phosphorylation of SLP-76 (Canis familiaris)
Activated ZAP-70 [plasma membrane] (Canis familiaris)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Phosphorylation of TBSMs in LAT (Canis familiaris)
Activated ZAP-70 [plasma membrane] (Canis familiaris)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Phosphorylation of CD3 and TCR zeta chains (Canis familiaris)
Activation of Lck (Canis familiaris)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Dephosphorylation of Lck-pY505 by CD45 (Canis familiaris)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Inactivation of LCK by PTPN22 (Canis familiaris)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Inactivation of Lck by Csk (Canis familiaris)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Phosphorylation of ITAM motifs in CD3 complexes (Canis familiaris)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Translocation of ZAP-70 to Immunological synapse (Canis familiaris)
Activation of ZAP-70 (Canis familiaris)
Activated ZAP-70 [plasma membrane] (Canis familiaris)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Canis familiaris)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
PTPN22 dephosphorylates ZAP70 (Canis familiaris)
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Canis familiaris)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Canis familiaris)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Phosphorylation of ZAP-70 by Lck (Canis familiaris)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Canis familiaris)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Canis familiaris)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Recruitment of ZAP-70 to phosphorylated ITAMs (Canis familiaris)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Canis familiaris)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Canis familiaris)
MHC Class II bearing antigen peptide [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Innate Immune System (Canis familiaris)
Complement cascade (Canis familiaris)
Initial triggering of complement (Canis familiaris)
Conversion of C2 into C2a and C2b (Canis familiaris)
C4 activators [plasma membrane] (Canis familiaris)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Conversion of C4 into C4a and C4b (Canis familiaris)
C4 activators [plasma membrane] (Canis familiaris)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Creation of C4 and C2 activators (Canis familiaris)
Classical antibody-mediated complement activation (Canis familiaris)
Activation of C1r (Canis familiaris)
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xC1R:2xC1S [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Activation of C1s (Canis familiaris)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Regulation of Complement cascade (Canis familiaris)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Canis familiaris)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Canis familiaris)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
C1-Inh binds and inactivates C1r, C1s (Canis familiaris)
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Canis familiaris)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Fcgamma receptor (FCGR) dependent phagocytosis (Canis familiaris)
FCGR activation (Canis familiaris)
Cross-linking of FCGRIA with IgG-coated Ag (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
IgG-Ag:FCGRIA:CD3G homodimer [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Cross-linking of FCGRIIA with IgG-coated Ag (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
IgG-Ag:FCGRIIA [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Cross-linking of FCGRIIIA with IgG-coated Ag (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
IgG-Ag:FCGRIIIA:CD3G/CD3Z dimers [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Recruitment of SYK to phosphorylated ITAMs (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Canis familiaris)
clustered IgG-Ag:FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Regulation of actin dynamics for phagocytic cup formation (Canis familiaris)
Activation of RAC1 by CRKII:DOCK180:ELMO (Canis familiaris)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Activation of RAC1 by VAV (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Phosphorylation of VAV (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Canis familiaris)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Recruitment of VAV1 to p-6Y-SYK (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Role of myosins in phagosome formation (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Role of phospholipids in phagocytosis (Canis familiaris)
PI3K binds to p-6Y-SYK (Canis familiaris)
PI3K:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
PI3K:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Phosphorylation and activation of PLCG (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Recruitment of PLCgamma to membrane (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Release of PLCG from FCGR (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Canis familiaris)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen [plasma membrane]
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
Class I MHC mediated antigen processing & presentation (Danio rerio)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Danio rerio)
Expression of peptide bound class I MHC on cell surface (Danio rerio)
Antigen peptide bound class I MHC [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Antigen processing-Cross presentation (Danio rerio)
ER-Phagosome pathway (Danio rerio)
Export of peptide loaded MHC class I complex to PM (Danio rerio)
Antigen peptide bound class I MHC [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Endosomal/Vacuolar pathway (Danio rerio)
Translocation of peptide bound MHC class I complex to cell surface (Danio rerio)
Antigen peptide bound class I MHC [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Signaling by the B Cell Receptor (BCR) (Danio rerio)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Danio rerio)
SYK autophosphorylates at the activated BCR (Danio rerio)
Antigen:p-BCR:SYK [plasma membrane] (Danio rerio)
Antigen:p-BCR [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK [plasma membrane] (Danio rerio)
Antigen:p-BCR [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Danio rerio)
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Danio rerio)
Antigen:p-BCR [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
SYK binds the activated BCR (Danio rerio)
Antigen:p-BCR [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Antigen:p-BCR:SYK [plasma membrane] (Danio rerio)
Antigen:p-BCR [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
p-6Y-SYK phosphorylates BLNK (SLP65) (Danio rerio)
Antigen:p-BCR:p-SYK [plasma membrane] (Danio rerio)
Antigen:p-BCR [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Danio rerio)
Antigen:p-BCR:p-SYK [plasma membrane] (Danio rerio)
Antigen:p-BCR [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Innate Immune System (Danio rerio)
Complement cascade (Danio rerio)
Initial triggering of complement (Danio rerio)
Conversion of C2 into C2a and C2b (Danio rerio)
C4 activators [plasma membrane] (Danio rerio)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Conversion of C4 into C4a and C4b (Danio rerio)
C4 activators [plasma membrane] (Danio rerio)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Creation of C4 and C2 activators (Danio rerio)
Classical antibody-mediated complement activation (Danio rerio)
Activation of C1r (Danio rerio)
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xC1R:2xC1S [plasma membrane] (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Activation of C1s (Danio rerio)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Regulation of Complement cascade (Danio rerio)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Danio rerio)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Danio rerio)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
C1-Inh binds and inactivates C1r, C1s (Danio rerio)
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Danio rerio)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Fcgamma receptor (FCGR) dependent phagocytosis (Danio rerio)
FCGR activation (Danio rerio)
Cross-linking of FCGRIIA with IgG-coated Ag (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
IgG-Ag:FCGRIIA [plasma membrane] (Danio rerio)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen [plasma membrane]
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Class I MHC mediated antigen processing & presentation (Gallus gallus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Gallus gallus)
Expression of peptide bound class I MHC on cell surface (Gallus gallus)
Antigen peptide bound class I MHC [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen processing-Cross presentation (Gallus gallus)
ER-Phagosome pathway (Gallus gallus)
Export of peptide loaded MHC class I complex to PM (Gallus gallus)
Antigen peptide bound class I MHC [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Endosomal/Vacuolar pathway (Gallus gallus)
Translocation of peptide bound MHC class I complex to cell surface (Gallus gallus)
Antigen peptide bound class I MHC [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Costimulation by the CD28 family (Gallus gallus)
PD-1 signaling (Gallus gallus)
Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Gallus gallus)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Gallus gallus)
Fc gamma receptors interact with antigen-bound IgG (Gallus gallus)
Antigen-bound Ig G Antibody [extracellular region] (Gallus gallus)
Antigen [plasma membrane]
Antigen-bound antibody bound to lymphoid Fc gamma receptors [plasma membrane] (Gallus gallus)
Antigen-bound Ig G Antibody [extracellular region] (Gallus gallus)
Antigen [plasma membrane]
TCR complex interacts with peptide antigen-presenting MHC Class I (Gallus gallus)
Antigen peptide bound class I MHC [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
TCR interacting with antigen-bearing MHC Class I [plasma membrane] (Gallus gallus)
Antigen peptide bound class I MHC [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Signaling by the B Cell Receptor (BCR) (Gallus gallus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Gallus gallus)
BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Gallus gallus)
BLNK (SLP-65) Signalosome [plasma membrane] (Gallus gallus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Gallus gallus)
Antigen:p-BCR:p-SYK [plasma membrane] (Gallus gallus)
Antigen:p-BCR [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
BTK binds BTK inhibitors (Gallus gallus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Gallus gallus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Gallus gallus)
Antigen:p-BCR:p-SYK [plasma membrane] (Gallus gallus)
Antigen:p-BCR [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
BTK:BTK inhibitors [plasma membrane] (Gallus gallus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Gallus gallus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Gallus gallus)
Antigen:p-BCR:p-SYK [plasma membrane] (Gallus gallus)
Antigen:p-BCR [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
SYK autophosphorylates at the activated BCR (Gallus gallus)
Antigen:p-BCR:SYK [plasma membrane] (Gallus gallus)
Antigen:p-BCR [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK [plasma membrane] (Gallus gallus)
Antigen:p-BCR [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Gallus gallus)
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Gallus gallus)
Antigen:p-BCR [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
SYK binds the activated BCR (Gallus gallus)
Antigen:p-BCR [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen:p-BCR:SYK [plasma membrane] (Gallus gallus)
Antigen:p-BCR [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
p-6Y-SYK phosphorylates BLNK (SLP65) (Gallus gallus)
Antigen:p-BCR:p-SYK [plasma membrane] (Gallus gallus)
Antigen:p-BCR [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Gallus gallus)
Antigen:p-BCR:p-SYK [plasma membrane] (Gallus gallus)
Antigen:p-BCR [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
TCR signaling (Gallus gallus)
Generation of second messenger molecules (Gallus gallus)
Phosphorylation of PLC-gamma1 (Gallus gallus)
Activated ZAP-70 [plasma membrane] (Gallus gallus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Phosphorylation of CD3 and TCR zeta chains (Gallus gallus)
Activation of Lck (Gallus gallus)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Dephosphorylation of Lck-pY505 by CD45 (Gallus gallus)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Inactivation of LCK by PTPN22 (Gallus gallus)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Inactivation of Lck by Csk (Gallus gallus)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Phosphorylation of ITAM motifs in CD3 complexes (Gallus gallus)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Translocation of ZAP-70 to Immunological synapse (Gallus gallus)
Activation of ZAP-70 (Gallus gallus)
Activated ZAP-70 [plasma membrane] (Gallus gallus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Gallus gallus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
PTPN22 dephosphorylates ZAP70 (Gallus gallus)
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Gallus gallus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Gallus gallus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Phosphorylation of ZAP-70 by Lck (Gallus gallus)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Gallus gallus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Gallus gallus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Recruitment of ZAP-70 to phosphorylated ITAMs (Gallus gallus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Gallus gallus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Gallus gallus)
MHC Class II bearing antigen peptide [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Innate Immune System (Gallus gallus)
Complement cascade (Gallus gallus)
Initial triggering of complement (Gallus gallus)
Conversion of C2 into C2a and C2b (Gallus gallus)
C4 activators [plasma membrane] (Gallus gallus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Conversion of C4 into C4a and C4b (Gallus gallus)
C4 activators [plasma membrane] (Gallus gallus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Creation of C4 and C2 activators (Gallus gallus)
Classical antibody-mediated complement activation (Gallus gallus)
Activation of C1r (Gallus gallus)
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xC1R:2xC1S [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Activation of C1s (Gallus gallus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Regulation of Complement cascade (Gallus gallus)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Gallus gallus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Gallus gallus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
C1-Inh binds and inactivates C1r, C1s (Gallus gallus)
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Gallus gallus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Fcgamma receptor (FCGR) dependent phagocytosis (Gallus gallus)
FCGR activation (Gallus gallus)
Cross-linking of FCGRIA with IgG-coated Ag (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
IgG-Ag:FCGRIA:CD3G homodimer [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Cross-linking of FCGRIIA with IgG-coated Ag (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
IgG-Ag:FCGRIIA [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Cross-linking of FCGRIIIA with IgG-coated Ag (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
IgG-Ag:FCGRIIIA:CD3G/CD3Z dimers [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Recruitment of SYK to phosphorylated ITAMs (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Gallus gallus)
clustered IgG-Ag:FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Regulation of actin dynamics for phagocytic cup formation (Gallus gallus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Gallus gallus)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Activation of RAC1 by VAV (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Phosphorylation of VAV (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Gallus gallus)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Recruitment of VAV1 to p-6Y-SYK (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Role of myosins in phagosome formation (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Role of phospholipids in phagocytosis (Gallus gallus)
PI3K binds to p-6Y-SYK (Gallus gallus)
PI3K:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
PI3K:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Phosphorylation and activation of PLCG (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Recruitment of PLCgamma to membrane (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Release of PLCG from FCGR (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Gallus gallus)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Innate Immune System (Gallus gallus)
Complement Cascade (Gallus gallus)
Creation of classical C3 convertase (Gallus gallus)
Classical antibody-mediated complement activation (Gallus gallus)
Activation of C1r within the C1complement complex (Gallus gallus)
IgM:Antigen:C1q:C1r:pro-C1s [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
IgM:Antigen:C1q:pro-C1r:pro-C1s [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Antigen bound antibody interacts with C1complement complex (Gallus gallus)
Antigen:IgM [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
IgM:Antigen:C1q:pro-C1r:pro-C1s [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
C1r activates C1s component within C1 complement complex (Gallus gallus)
IgM:Antigen:C1q:C1r:pro-C1s [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
IgM:Antigen:Cqrs(activated C1r and C1s) [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Cleavage of factor B to form classical C3 convertase (Gallus gallus)
C4:factor B activator [plasma membrane] (Gallus gallus)
IgM:Antigen:Cqrs(activated C1r and C1s) [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
IgM:Antigen:Cqrs(activated C1r and C1s) [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Proteolytic cleavage of complement factor C4 (Gallus gallus)
C4:factor B activator [plasma membrane] (Gallus gallus)
IgM:Antigen:Cqrs(activated C1r and C1s) [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
IgM:Antigen:Cqrs(activated C1r and C1s) [plasma membrane] (Gallus gallus)
Antigen [plasma membrane]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
FCGR3A-mediated IL10 synthesis (Homo sapiens)
Phosphorylation and activation of PLCG due to FCGR3A effect (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
SARS-CoV Infections (Homo sapiens)
Potential therapeutics for SARS (Homo sapiens)
BTK binds BTK inhibitors (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
BTK:BTK inhibitors [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)
Expression of peptide bound class I MHC on cell surface (Homo sapiens)
Antigen peptide bound class I MHC [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen processing-Cross presentation (Homo sapiens)
ER-Phagosome pathway (Homo sapiens)
Export of peptide loaded MHC class I complex to PM (Homo sapiens)
Antigen peptide bound class I MHC [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Endosomal/Vacuolar pathway (Homo sapiens)
Translocation of peptide bound MHC class I complex to cell surface (Homo sapiens)
Antigen peptide bound class I MHC [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Costimulation by the CD28 family (Homo sapiens)
PD-1 signaling (Homo sapiens)
Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Homo sapiens)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Homo sapiens)
C3d-complexed antigen binds to complement receptor (Homo sapiens)
C3d complexed with antigen [extracellular region] (Homo sapiens)
Antigen [plasma membrane]
Complex of CD19, CD81, CD225 and CD21 with C3d-bound Antigen [plasma membrane] (Homo sapiens)
C3d complexed with antigen [extracellular region] (Homo sapiens)
Antigen [plasma membrane]
Fc gamma receptors interact with antigen-bound IgG (Homo sapiens)
Antigen-bound Ig G Antibody [extracellular region] (Homo sapiens)
Antigen [plasma membrane]
Antigen-bound antibody bound to lymphoid Fc gamma receptors [plasma membrane] (Homo sapiens)
Antigen-bound Ig G Antibody [extracellular region] (Homo sapiens)
Antigen [plasma membrane]
TCR complex interacts with peptide antigen-presenting MHC Class I (Homo sapiens)
Antigen peptide bound class I MHC [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
TCR interacting with antigen-bearing MHC Class I [plasma membrane] (Homo sapiens)
Antigen peptide bound class I MHC [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Signaling by the B Cell Receptor (BCR) (Homo sapiens)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Homo sapiens)
BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Homo sapiens)
BLNK (SLP-65) Signalosome [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
BTK autophosphorylates (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:p-Y223,Y551-BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:p-Y551-BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
BTK binds BTK inhibitors (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
BTK:BTK inhibitors [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Homo sapiens)
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Phosphorylated BTK phosphorylates PLCG2 (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:p-Y223,Y551-BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
BLNK (SLP-65) Signalosome [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
SYK autophosphorylates at the activated BCR (Homo sapiens)
Antigen:p-BCR:SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Homo sapiens)
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
SYK binds the activated BCR (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen:p-BCR:SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
p-6Y-SYK phosphorylates BLNK (SLP65) (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
p-SYK and LYN phosphorylate BTK (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:p-Y551-BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
LYN, p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Antigen:p-BCR:p-SYK [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
CD22 mediated BCR regulation (Homo sapiens)
CD22 binds B-cell receptor (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
CD22:Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
LYN phosphorylates CD22 (Homo sapiens)
CD22:Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
SHP1 binds p-CD22 (Homo sapiens)
PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Homo sapiens)
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen:p-BCR [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
TCR signaling (Homo sapiens)
Downstream TCR signaling (Homo sapiens)
Change of PKC theta conformation (Homo sapiens)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Generation of second messenger molecules (Homo sapiens)
Phosphorylation of PLC-gamma1 (Homo sapiens)
ZAP-70 and ITK tyrosine kinases [plasma membrane] (Homo sapiens)
Activated ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Phosphorylation of SLP-76 (Homo sapiens)
Activated ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Phosphorylation of TBSMs in LAT (Homo sapiens)
Activated ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Phosphorylation of CD3 and TCR zeta chains (Homo sapiens)
Activation of Lck (Homo sapiens)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Dephosphorylation of Lck-pY505 by CD45 (Homo sapiens)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Inactivation of LCK by PTPN22 (Homo sapiens)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Inactivation of Lck by Csk (Homo sapiens)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Phosphorylation of ITAM motifs in CD3 complexes (Homo sapiens)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Translocation of ZAP-70 to Immunological synapse (Homo sapiens)
Activation of ZAP-70 (Homo sapiens)
Activated ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
PTPN22 dephosphorylates ZAP70 (Homo sapiens)
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Phosphorylation of ZAP-70 by Lck (Homo sapiens)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Recruitment of ZAP-70 to phosphorylated ITAMs (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Innate Immune System (Homo sapiens)
Complement cascade (Homo sapiens)
Initial triggering of complement (Homo sapiens)
Conversion of C2 into C2a and C2b (Homo sapiens)
C4 activators [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Conversion of C4 into C4a and C4b (Homo sapiens)
C4 activators [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Creation of C4 and C2 activators (Homo sapiens)
Classical antibody-mediated complement activation (Homo sapiens)
Activation of C1r (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xC1R:2xC1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Activation of C1s (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Regulation of Complement cascade (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
C1-Inh binds and inactivates C1r, C1s (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
FCGR activation (Homo sapiens)
Cross-linking of FCGRIA with IgG-coated Ag (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
IgG-Ag:FCGRIA:CD3G homodimer [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Cross-linking of FCGRIIA with IgG-coated Ag (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
IgG-Ag:FCGRIIA [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Cross-linking of FCGRIIIA with IgG-coated Ag (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
IgG-Ag:FCGRIIIA:CD3G/CD3Z dimers [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Phosphorylation of SYK by Src kinases (Homo sapiens)
clustered IgG-Ag:p-FCGRs:SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Recruitment of SYK to phosphorylated ITAMs (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Homo sapiens)
clustered IgG-Ag:FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
Activation of RAC1 by CRKII:DOCK180:ELMO (Homo sapiens)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Activation of RAC1 by VAV (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Phosphorylation of VAV (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Homo sapiens)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Recruitment of VAV1 to p-6Y-SYK (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Role of myosins in phagosome formation (Homo sapiens)
clustered IgG-Ag:p-FCGRs [phagocytic cup] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Role of phospholipids in phagocytosis (Homo sapiens)
PI3K binds to p-6Y-SYK (Homo sapiens)
PI3K:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
PI3K:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Phosphorylation and activation of PLCG (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Recruitment of PLCgamma to membrane (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Release of PLCG from FCGR (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen [plasma membrane]
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Class I MHC mediated antigen processing & presentation (Mus musculus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Mus musculus)
Expression of peptide bound class I MHC on cell surface (Mus musculus)
Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen processing-Cross presentation (Mus musculus)
ER-Phagosome pathway (Mus musculus)
Export of peptide loaded MHC class I complex to PM (Mus musculus)
Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Endosomal/Vacuolar pathway (Mus musculus)
Translocation of peptide bound MHC class I complex to cell surface (Mus musculus)
Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Costimulation by the CD28 family (Mus musculus)
PD-1 signaling (Mus musculus)
Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Mus musculus)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Mus musculus)
C3d-complexed antigen binds to complement receptor (Mus musculus)
C3d complexed with antigen [extracellular region] (Mus musculus)
Antigen [plasma membrane]
Complex of CD19, CD81, CD225 and CD21 with C3d-bound Antigen [plasma membrane] (Mus musculus)
C3d complexed with antigen [extracellular region] (Mus musculus)
Antigen [plasma membrane]
Fc gamma receptors interact with antigen-bound IgG (Mus musculus)
Antigen-bound Ig G Antibody [extracellular region] (Mus musculus)
Antigen [plasma membrane]
Antigen-bound antibody bound to lymphoid Fc gamma receptors [plasma membrane] (Mus musculus)
Antigen-bound Ig G Antibody [extracellular region] (Mus musculus)
Antigen [plasma membrane]
TCR complex interacts with peptide antigen-presenting MHC Class I (Mus musculus)
Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
TCR interacting with antigen-bearing MHC Class I [plasma membrane] (Mus musculus)
Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Signaling by the B Cell Receptor (BCR) (Mus musculus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Mus musculus)
BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Mus musculus)
BLNK (SLP-65) Signalosome [plasma membrane] (Mus musculus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Mus musculus)
Antigen:p-BCR:p-SYK [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
BTK binds BTK inhibitors (Mus musculus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Mus musculus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Mus musculus)
Antigen:p-BCR:p-SYK [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
BTK:BTK inhibitors [plasma membrane] (Mus musculus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Mus musculus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Mus musculus)
Antigen:p-BCR:p-SYK [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 (Mus musculus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Mus musculus)
Antigen:p-BCR:p-SYK [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Mus musculus)
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Mus musculus)
Antigen:p-BCR:p-SYK [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
SYK autophosphorylates at the activated BCR (Mus musculus)
Antigen:p-BCR:SYK [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Mus musculus)
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
SYK binds the activated BCR (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen:p-BCR:SYK [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
p-6Y-SYK phosphorylates BLNK (SLP65) (Mus musculus)
Antigen:p-BCR:p-SYK [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Mus musculus)
Antigen:p-BCR:p-SYK [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
CD22 mediated BCR regulation (Mus musculus)
CD22 binds B-cell receptor (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
CD22:Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
LYN phosphorylates CD22 (Mus musculus)
CD22:Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
SHP1 binds p-CD22 (Mus musculus)
PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Mus musculus)
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen:p-BCR [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
TCR signaling (Mus musculus)
Downstream TCR signaling (Mus musculus)
Change of PKC theta conformation (Mus musculus)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Generation of second messenger molecules (Mus musculus)
Phosphorylation of PLC-gamma1 (Mus musculus)
ZAP-70 and ITK tyrosine kinases [plasma membrane] (Mus musculus)
Activated ZAP-70 [plasma membrane] (Mus musculus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Phosphorylation of SLP-76 (Mus musculus)
Activated ZAP-70 [plasma membrane] (Mus musculus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Phosphorylation of TBSMs in LAT (Mus musculus)
Activated ZAP-70 [plasma membrane] (Mus musculus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Phosphorylation of CD3 and TCR zeta chains (Mus musculus)
Activation of Lck (Mus musculus)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Dephosphorylation of Lck-pY505 by CD45 (Mus musculus)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Inactivation of LCK by PTPN22 (Mus musculus)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Inactivation of Lck by Csk (Mus musculus)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Phosphorylation of ITAM motifs in CD3 complexes (Mus musculus)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Translocation of ZAP-70 to Immunological synapse (Mus musculus)
Activation of ZAP-70 (Mus musculus)
Activated ZAP-70 [plasma membrane] (Mus musculus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Mus musculus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
PTPN22 dephosphorylates ZAP70 (Mus musculus)
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Mus musculus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Mus musculus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Phosphorylation of ZAP-70 by Lck (Mus musculus)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Mus musculus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
phospho tyrosine ZAP-70 [plasma membrane] (Mus musculus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Recruitment of ZAP-70 to phosphorylated ITAMs (Mus musculus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Mus musculus)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Mus musculus)
MHC Class II bearing antigen peptide [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Innate Immune System (Mus musculus)
Complement cascade (Mus musculus)
Initial triggering of complement (Mus musculus)
Conversion of C2 into C2a and C2b (Mus musculus)
C4 activators [plasma membrane] (Mus musculus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Mus musculus)
Antigen:IgG [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Conversion of C4 into C4a and C4b (Mus musculus)
C4 activators [plasma membrane] (Mus musculus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Mus musculus)
Antigen:IgG [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Creation of C4 and C2 activators (Mus musculus)
Classical antibody-mediated complement activation (Mus musculus)
Activation of C1r (Mus musculus)
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Mus musculus)
Antigen:IgG [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xC1R:2xC1S [plasma membrane] (Mus musculus)
Antigen:IgG [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Activation of C1s (Mus musculus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Mus musculus)
Antigen:IgG [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Mus musculus)
Antigen:IgG [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Regulation of Complement cascade (Mus musculus)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Mus musculus)
Antigen:IgG [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Mus musculus)
Antigen:IgG [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Mus musculus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Mus musculus)
Antigen:IgG [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Mus musculus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Mus musculus)
Antigen:IgG [plasma membrane] (Mus musculus)
Antigen [plasma membrane]
C1-Inh binds and inactivates C1r, C1s (Mus musculus)
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Mus musculus)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Mus musculus)
Antigen:IgG [plasma membrane] (Mus musculus)
