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Disclaimer
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Table of Contents
DOIs
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How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
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Computationally inferred events
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Citing us
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SPG [plasma membrane]
Stable Identifier
R-ALL-1606609
Type
Chemical Compound [SimpleEntity]
Compartment
plasma membrane
Synonyms
sphingosine
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of lipids (Bos taurus)
Sphingolipid metabolism (Bos taurus)
Glycosphingolipid metabolism (Bos taurus)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Bos taurus)
SPG [plasma membrane]
Signal Transduction (Caenorhabditis elegans)
Signaling by Nuclear Receptors (Caenorhabditis elegans)
ESR-mediated signaling (Caenorhabditis elegans)
Extra-nuclear estrogen signaling (Caenorhabditis elegans)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Caenorhabditis elegans)
SPG [plasma membrane]
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Sphingolipid metabolism (Canis familiaris)
Glycosphingolipid metabolism (Canis familiaris)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Canis familiaris)
SPG [plasma membrane]
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
Extra-nuclear estrogen signaling (Canis familiaris)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Canis familiaris)
SPG [plasma membrane]
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
VEGFR2 mediated cell proliferation (Canis familiaris)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Canis familiaris)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Canis familiaris)
SPG [plasma membrane]
Metabolism (Danio rerio)
Metabolism of lipids (Danio rerio)
Sphingolipid metabolism (Danio rerio)
Glycosphingolipid metabolism (Danio rerio)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Danio rerio)
SPG [plasma membrane]
Signal Transduction (Danio rerio)
Signaling by Nuclear Receptors (Danio rerio)
ESR-mediated signaling (Danio rerio)
Extra-nuclear estrogen signaling (Danio rerio)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Danio rerio)
SPG [plasma membrane]
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by VEGF (Danio rerio)
VEGFA-VEGFR2 Pathway (Danio rerio)
VEGFR2 mediated cell proliferation (Danio rerio)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Danio rerio)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Danio rerio)
SPG [plasma membrane]
Metabolism (Dictyostelium discoideum)
Metabolism of lipids (Dictyostelium discoideum)
Sphingolipid metabolism (Dictyostelium discoideum)
Glycosphingolipid metabolism (Dictyostelium discoideum)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Dictyostelium discoideum)
SPG [plasma membrane]
Signal Transduction (Dictyostelium discoideum)
Signaling by Nuclear Receptors (Dictyostelium discoideum)
ESR-mediated signaling (Dictyostelium discoideum)
Extra-nuclear estrogen signaling (Dictyostelium discoideum)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Dictyostelium discoideum)
SPG [plasma membrane]
Signaling by Receptor Tyrosine Kinases (Dictyostelium discoideum)
Signaling by VEGF (Dictyostelium discoideum)
VEGFA-VEGFR2 Pathway (Dictyostelium discoideum)
VEGFR2 mediated cell proliferation (Dictyostelium discoideum)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Dictyostelium discoideum)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Dictyostelium discoideum)
SPG [plasma membrane]
Metabolism (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Sphingolipid metabolism (Drosophila melanogaster)
Glycosphingolipid metabolism (Drosophila melanogaster)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Drosophila melanogaster)
SPG [plasma membrane]
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Extra-nuclear estrogen signaling (Drosophila melanogaster)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Drosophila melanogaster)
SPG [plasma membrane]
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated cell proliferation (Drosophila melanogaster)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Drosophila melanogaster)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Drosophila melanogaster)
SPG [plasma membrane]
Metabolism (Gallus gallus)
Metabolism of lipids (Gallus gallus)
Sphingolipid metabolism (Gallus gallus)
Glycosphingolipid metabolism (Gallus gallus)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Gallus gallus)
SPG [plasma membrane]
Signal Transduction (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
ESR-mediated signaling (Gallus gallus)
Extra-nuclear estrogen signaling (Gallus gallus)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Gallus gallus)
SPG [plasma membrane]
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
VEGFR2 mediated cell proliferation (Gallus gallus)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Gallus gallus)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Gallus gallus)
SPG [plasma membrane]
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Sphingolipid metabolism (Homo sapiens)
Glycosphingolipid metabolism (Homo sapiens)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Homo sapiens)
SPG [plasma membrane]
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Extra-nuclear estrogen signaling (Homo sapiens)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Homo sapiens)
SPG [plasma membrane]
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
VEGFR2 mediated cell proliferation (Homo sapiens)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Homo sapiens)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Homo sapiens)
SPG [plasma membrane]
Metabolism (Mus musculus)
Metabolism of lipids (Mus musculus)
Sphingolipid metabolism (Mus musculus)
Glycosphingolipid metabolism (Mus musculus)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Mus musculus)
SPG [plasma membrane]
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
ESR-mediated signaling (Mus musculus)
Extra-nuclear estrogen signaling (Mus musculus)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Mus musculus)
SPG [plasma membrane]
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
VEGFR2 mediated cell proliferation (Mus musculus)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Mus musculus)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Mus musculus)
SPG [plasma membrane]
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Sphingolipid metabolism (Rattus norvegicus)
Glycosphingolipid metabolism (Rattus norvegicus)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Rattus norvegicus)
SPG [plasma membrane]
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
ESR-mediated signaling (Rattus norvegicus)
Extra-nuclear estrogen signaling (Rattus norvegicus)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Rattus norvegicus)
SPG [plasma membrane]
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by VEGF (Rattus norvegicus)
VEGFA-VEGFR2 Pathway (Rattus norvegicus)
VEGFR2 mediated cell proliferation (Rattus norvegicus)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Rattus norvegicus)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Rattus norvegicus)
SPG [plasma membrane]
Signal Transduction (Saccharomyces cerevisiae)
Signaling by Nuclear Receptors (Saccharomyces cerevisiae)
ESR-mediated signaling (Saccharomyces cerevisiae)
Extra-nuclear estrogen signaling (Saccharomyces cerevisiae)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Saccharomyces cerevisiae)
SPG [plasma membrane]
Signal Transduction (Schizosaccharomyces pombe)
Signaling by Nuclear Receptors (Schizosaccharomyces pombe)
ESR-mediated signaling (Schizosaccharomyces pombe)
Extra-nuclear estrogen signaling (Schizosaccharomyces pombe)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Schizosaccharomyces pombe)
SPG [plasma membrane]
Metabolism (Sus scrofa)
Metabolism of lipids (Sus scrofa)
Sphingolipid metabolism (Sus scrofa)
Glycosphingolipid metabolism (Sus scrofa)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Sus scrofa)
SPG [plasma membrane]
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
ESR-mediated signaling (Sus scrofa)
Extra-nuclear estrogen signaling (Sus scrofa)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Sus scrofa)
SPG [plasma membrane]
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by VEGF (Sus scrofa)
VEGFA-VEGFR2 Pathway (Sus scrofa)
VEGFR2 mediated cell proliferation (Sus scrofa)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Sus scrofa)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Sus scrofa)
SPG [plasma membrane]
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Sphingolipid metabolism (Xenopus tropicalis)
Glycosphingolipid metabolism (Xenopus tropicalis)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Xenopus tropicalis)
SPG [plasma membrane]
Signal Transduction (Xenopus tropicalis)
Signaling by Nuclear Receptors (Xenopus tropicalis)
ESR-mediated signaling (Xenopus tropicalis)
Extra-nuclear estrogen signaling (Xenopus tropicalis)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Xenopus tropicalis)
SPG [plasma membrane]
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by VEGF (Xenopus tropicalis)
VEGFA-VEGFR2 Pathway (Xenopus tropicalis)
VEGFR2 mediated cell proliferation (Xenopus tropicalis)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Xenopus tropicalis)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Xenopus tropicalis)
SPG [plasma membrane]
External Reference Information
External Reference
sphingosine [ChEBI:16393]
Participates
as an output of
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Dictyostelium discoideum)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Drosophila melanogaster)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Gallus gallus)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Xenopus tropicalis)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Danio rerio)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Sus scrofa)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Bos taurus)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Canis familiaris)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Rattus norvegicus)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Mus musculus)
Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane) (Homo sapiens)
as a component of
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Sus scrofa)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Dictyostelium discoideum)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Danio rerio)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Rattus norvegicus)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Gallus gallus)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Mus musculus)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Xenopus tropicalis)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Drosophila melanogaster)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Canis familiaris)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Homo sapiens)
as an input of
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Saccharomyces cerevisiae)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Schizosaccharomyces pombe)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Dictyostelium discoideum)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Caenorhabditis elegans)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Drosophila melanogaster)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Xenopus tropicalis)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Danio rerio)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Sus scrofa)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Canis familiaris)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Rattus norvegicus)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Mus musculus)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Homo sapiens)
SPHK1 phosphorylates sphingosine in response to E2 stimulation (Gallus gallus)
Other forms of this molecule
SPG [lysosomal lumen]
SPG [Golgi membrane]
SPG [extracellular region]
SPG [cytosol]
SPG [endoplasmic reticulum membrane]
Cross References
COMPOUND
C00319
HMDB Metabolite
HMDB0000252
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![SPG [plasma membrane] icon](/icon/R-ICO-013855.svg){kind=icon}
