Reactome | guanosine 5'-monophosphate [cytosol]

guanosine 5'-monophosphate

Stable Identifier

R-ALL-113578

Type

Chemical Compound [SimpleEntity]

Compartment

cytosol

Synonyms

GMP, Guanosine 5'-phosphate, Guanosine monophosphate, Guanylic acid

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External Reference Information

External Reference

guanosine 5'-monophosphate [ChEBI:17345]

Participant Of

hasMember

(d)AMP, (d)GMP, (d)IMP [cytosol]
(d)GMP [cytosol]
(d)GMP, (d)IMP [cytosol]
GMP, IMP [cytosol]

input

GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)

output

5' to 3' Exoribonuclease Digestion of Decapped mRNA (yeast)
5' to 3' exoribonuclease hydrolyzes decapped mRNA
cGMP is degraded by PDEs
cGMP is degraded by PDEs
cGMP is degraded by PDEs
cGMP is degraded by PDEs
cGMP is degraded by PDEs
cGMP is degraded by PDEs
cGMP is degraded by PDEs
cGMP is degraded by PDEs
cGMP is degraded by PDEs
cGMP is degraded by PDEs
cGMP is degraded by PDEs
cGMP is degraded by PDEs
cGMP is degraded by PDEs
cGMP is degraded by PDEs
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
PDE6 hydrolyses cGMP to GMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate

This entity regulates

Negatively

inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
Formation of PPAT dimers

Positively

Formation of PPAT tetramers
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer

Other forms of this molecule

guanosine 5'-monophosphate [endocytic vesicle lumen]

guanosine 5'-monophosphate [Golgi lumen]

guanosine 5'-monophosphate [extracellular region]

GMP [mitochondrial matrix]

guanosine 5'-monophosphate [nucleoplasm]

Cross References

COMPOUND

C00144

PubChem Substance

8145524

HMDB Metabolite

HMDB0001397

ZINC

000002159505