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XMP [cytosol]
Stable Identifier
R-ALL-111584
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
xanthosine 5'-monophosphate, 5'-xanthylic acid, xanthylic acid, 5'-xanthylate(2-)
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of nucleotides (Bos taurus)
Nucleotide biosynthesis (Bos taurus)
Purine ribonucleoside monophosphate biosynthesis (Bos taurus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Bos taurus)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Bos taurus)
XMP [cytosol]
Nucleotide catabolism (Bos taurus)
Purine catabolism (Bos taurus)
ITPA hydrolyses XTP to XMP (Bos taurus)
XMP [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of nucleotides (Caenorhabditis elegans)
Nucleotide biosynthesis (Caenorhabditis elegans)
Purine ribonucleoside monophosphate biosynthesis (Caenorhabditis elegans)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Caenorhabditis elegans)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Caenorhabditis elegans)
XMP [cytosol]
Nucleotide catabolism (Caenorhabditis elegans)
Purine catabolism (Caenorhabditis elegans)
ITPA hydrolyses XTP to XMP (Caenorhabditis elegans)
XMP [cytosol]
Metabolism (Canis familiaris)
Metabolism of nucleotides (Canis familiaris)
Nucleotide biosynthesis (Canis familiaris)
Purine ribonucleoside monophosphate biosynthesis (Canis familiaris)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Canis familiaris)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Canis familiaris)
XMP [cytosol]
Nucleotide catabolism (Canis familiaris)
Purine catabolism (Canis familiaris)
ITPA hydrolyses XTP to XMP (Canis familiaris)
XMP [cytosol]
Metabolism (Danio rerio)
Metabolism of nucleotides (Danio rerio)
Nucleotide biosynthesis (Danio rerio)
Purine ribonucleoside monophosphate biosynthesis (Danio rerio)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Danio rerio)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Danio rerio)
XMP [cytosol]
Nucleotide catabolism (Danio rerio)
Purine catabolism (Danio rerio)
ITPA hydrolyses XTP to XMP (Danio rerio)
XMP [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of nucleotides (Dictyostelium discoideum)
Nucleotide biosynthesis (Dictyostelium discoideum)
Purine ribonucleoside monophosphate biosynthesis (Dictyostelium discoideum)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Dictyostelium discoideum)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Dictyostelium discoideum)
XMP [cytosol]
Nucleotide catabolism (Dictyostelium discoideum)
Purine catabolism (Dictyostelium discoideum)
ITPA hydrolyses XTP to XMP (Dictyostelium discoideum)
XMP [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of nucleotides (Drosophila melanogaster)
Nucleotide biosynthesis (Drosophila melanogaster)
Purine ribonucleoside monophosphate biosynthesis (Drosophila melanogaster)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Drosophila melanogaster)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Drosophila melanogaster)
XMP [cytosol]
Nucleotide catabolism (Drosophila melanogaster)
Purine catabolism (Drosophila melanogaster)
ITPA hydrolyses XTP to XMP (Drosophila melanogaster)
XMP [cytosol]
Metabolism (Gallus gallus)
Nucleotide metabolism (Gallus gallus)
Purine metabolism (Gallus gallus)
De novo synthesis of GMP (Gallus gallus)
inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ (Gallus gallus)
XMP [cytosol]
xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate (Gallus gallus)
XMP [cytosol]
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Nucleotide biosynthesis (Homo sapiens)
Purine ribonucleoside monophosphate biosynthesis (Homo sapiens)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Homo sapiens)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Homo sapiens)
XMP [cytosol]
Nucleotide catabolism (Homo sapiens)
Purine catabolism (Homo sapiens)
ITPA hydrolyses XTP to XMP (Homo sapiens)
XMP [cytosol]
Metabolism (Mus musculus)
Metabolism of nucleotides (Mus musculus)
Nucleotide biosynthesis (Mus musculus)
Purine ribonucleoside monophosphate biosynthesis (Mus musculus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Mus musculus)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Mus musculus)
XMP [cytosol]
Nucleotide catabolism (Mus musculus)
Purine catabolism (Mus musculus)
ITPA hydrolyses XTP to XMP (Mus musculus)
XMP [cytosol]
Metabolism (Plasmodium falciparum)
Metabolism of nucleotides (Plasmodium falciparum)
Nucleotide biosynthesis (Plasmodium falciparum)
Purine ribonucleoside monophosphate biosynthesis (Plasmodium falciparum)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Plasmodium falciparum)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Plasmodium falciparum)
XMP [cytosol]
Nucleotide catabolism (Plasmodium falciparum)
Purine catabolism (Plasmodium falciparum)
ITPA hydrolyses XTP to XMP (Plasmodium falciparum)
XMP [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of nucleotides (Rattus norvegicus)
Nucleotide biosynthesis (Rattus norvegicus)
Purine ribonucleoside monophosphate biosynthesis (Rattus norvegicus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Rattus norvegicus)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Rattus norvegicus)
XMP [cytosol]
Nucleotide catabolism (Rattus norvegicus)
Purine catabolism (Rattus norvegicus)
ITPA hydrolyses XTP to XMP (Rattus norvegicus)
XMP [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of nucleotides (Saccharomyces cerevisiae)
Nucleotide biosynthesis (Saccharomyces cerevisiae)
Purine ribonucleoside monophosphate biosynthesis (Saccharomyces cerevisiae)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Saccharomyces cerevisiae)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Saccharomyces cerevisiae)
XMP [cytosol]
Nucleotide catabolism (Saccharomyces cerevisiae)
Purine catabolism (Saccharomyces cerevisiae)
ITPA hydrolyses XTP to XMP (Saccharomyces cerevisiae)
XMP [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of nucleotides (Schizosaccharomyces pombe)
Nucleotide biosynthesis (Schizosaccharomyces pombe)
Purine ribonucleoside monophosphate biosynthesis (Schizosaccharomyces pombe)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Schizosaccharomyces pombe)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Schizosaccharomyces pombe)
XMP [cytosol]
Nucleotide catabolism (Schizosaccharomyces pombe)
Purine catabolism (Schizosaccharomyces pombe)
ITPA hydrolyses XTP to XMP (Schizosaccharomyces pombe)
XMP [cytosol]
Metabolism (Sus scrofa)
Metabolism of nucleotides (Sus scrofa)
Nucleotide biosynthesis (Sus scrofa)
Purine ribonucleoside monophosphate biosynthesis (Sus scrofa)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Sus scrofa)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Sus scrofa)
XMP [cytosol]
Nucleotide catabolism (Sus scrofa)
Purine catabolism (Sus scrofa)
ITPA hydrolyses XTP to XMP (Sus scrofa)
XMP [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of nucleotides (Xenopus tropicalis)
Nucleotide biosynthesis (Xenopus tropicalis)
Purine ribonucleoside monophosphate biosynthesis (Xenopus tropicalis)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Xenopus tropicalis)
XMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Xenopus tropicalis)
XMP [cytosol]
Nucleotide catabolism (Xenopus tropicalis)
Purine catabolism (Xenopus tropicalis)
ITPA hydrolyses XTP to XMP (Xenopus tropicalis)
XMP [cytosol]
External Reference Information
External Reference
5'-xanthylate(2-) [ChEBI:57464]
Participates
as an input of
xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate (Gallus gallus)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Homo sapiens)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Mus musculus)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Rattus norvegicus)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Canis familiaris)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Bos taurus)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Sus scrofa)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Danio rerio)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Xenopus tropicalis)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Gallus gallus)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Drosophila melanogaster)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Caenorhabditis elegans)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Dictyostelium discoideum)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Schizosaccharomyces pombe)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Saccharomyces cerevisiae)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Plasmodium falciparum)
as an output of
inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ (Gallus gallus)
ITPA hydrolyses XTP to XMP (Plasmodium falciparum)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Homo sapiens)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Mus musculus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Rattus norvegicus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Canis familiaris)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Bos taurus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Sus scrofa)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Danio rerio)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Xenopus tropicalis)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Gallus gallus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Drosophila melanogaster)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Caenorhabditis elegans)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Dictyostelium discoideum)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Schizosaccharomyces pombe)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Saccharomyces cerevisiae)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Plasmodium falciparum)
ITPA hydrolyses XTP to XMP (Schizosaccharomyces pombe)
ITPA hydrolyses XTP to XMP (Homo sapiens)
ITPA hydrolyses XTP to XMP (Mus musculus)
ITPA hydrolyses XTP to XMP (Rattus norvegicus)
ITPA hydrolyses XTP to XMP (Canis familiaris)
ITPA hydrolyses XTP to XMP (Bos taurus)
ITPA hydrolyses XTP to XMP (Sus scrofa)
ITPA hydrolyses XTP to XMP (Danio rerio)
ITPA hydrolyses XTP to XMP (Xenopus tropicalis)
ITPA hydrolyses XTP to XMP (Gallus gallus)
ITPA hydrolyses XTP to XMP (Drosophila melanogaster)
ITPA hydrolyses XTP to XMP (Caenorhabditis elegans)
ITPA hydrolyses XTP to XMP (Dictyostelium discoideum)
ITPA hydrolyses XTP to XMP (Saccharomyces cerevisiae)
This entity regulates
Negatively
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Plasmodium falciparum)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Saccharomyces cerevisiae)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Schizosaccharomyces pombe)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Dictyostelium discoideum)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Caenorhabditis elegans)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Drosophila melanogaster)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Gallus gallus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Xenopus tropicalis)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Danio rerio)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Sus scrofa)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Bos taurus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Canis familiaris)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Rattus norvegicus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Mus musculus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]
(Homo sapiens)
Cross References
COMPOUND
C00655
ZINC
000004228292
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