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SPN [cytosol]
Stable Identifier
R-ALL-353560
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
spermine
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Metabolism of polyamines (Bos taurus)
Interconversion of polyamines (Bos taurus)
Spermine => N-acetylated spermine (Bos taurus)
SPN [cytosol]
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Bos taurus)
SPN [cytosol]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of bile salts and organic acids, metal ions and amine compounds (Bos taurus)
Organic cation/anion/zwitterion transport (Bos taurus)
Organic cation transport (Bos taurus)
OCT1 transports organic cations into hepatic cells (Bos taurus)
OCT1 substrates [cytosol]
SPN [cytosol]
OCT1 transports organic cations out of hepatic cells (Bos taurus)
OCT1 substrates [cytosol]
SPN [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Metabolism of polyamines (Caenorhabditis elegans)
Interconversion of polyamines (Caenorhabditis elegans)
Spermine => N-acetylated spermine (Caenorhabditis elegans)
SPN [cytosol]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of bile salts and organic acids, metal ions and amine compounds (Caenorhabditis elegans)
Organic cation/anion/zwitterion transport (Caenorhabditis elegans)
Organic cation transport (Caenorhabditis elegans)
OCT1 transports organic cations into hepatic cells (Caenorhabditis elegans)
OCT1 substrates [cytosol]
SPN [cytosol]
OCT1 transports organic cations out of hepatic cells (Caenorhabditis elegans)
OCT1 substrates [cytosol]
SPN [cytosol]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Metabolism of polyamines (Canis familiaris)
Interconversion of polyamines (Canis familiaris)
Spermine => N-acetylated spermine (Canis familiaris)
SPN [cytosol]
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Canis familiaris)
SPN [cytosol]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of bile salts and organic acids, metal ions and amine compounds (Canis familiaris)
Organic cation/anion/zwitterion transport (Canis familiaris)
Organic cation transport (Canis familiaris)
OCT1 transports organic cations into hepatic cells (Canis familiaris)
OCT1 substrates [cytosol]
SPN [cytosol]
OCT1 transports organic cations out of hepatic cells (Canis familiaris)
OCT1 substrates [cytosol]
SPN [cytosol]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Metabolism of polyamines (Danio rerio)
Interconversion of polyamines (Danio rerio)
Spermine => N-acetylated spermine (Danio rerio)
SPN [cytosol]
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Danio rerio)
SPN [cytosol]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of bile salts and organic acids, metal ions and amine compounds (Danio rerio)
Organic cation/anion/zwitterion transport (Danio rerio)
Organic cation transport (Danio rerio)
OCT1 transports organic cations into hepatic cells (Danio rerio)
OCT1 substrates [cytosol]
SPN [cytosol]
OCT1 transports organic cations out of hepatic cells (Danio rerio)
OCT1 substrates [cytosol]
SPN [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Metabolism of polyamines (Dictyostelium discoideum)
Interconversion of polyamines (Dictyostelium discoideum)
Spermine => N-acetylated spermine (Dictyostelium discoideum)
SPN [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Metabolism of polyamines (Drosophila melanogaster)
Interconversion of polyamines (Drosophila melanogaster)
Spermine => N-acetylated spermine (Drosophila melanogaster)
SPN [cytosol]
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Drosophila melanogaster)
SPN [cytosol]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of bile salts and organic acids, metal ions and amine compounds (Drosophila melanogaster)
Organic cation/anion/zwitterion transport (Drosophila melanogaster)
Organic cation transport (Drosophila melanogaster)
OCT1 transports organic cations into hepatic cells (Drosophila melanogaster)
OCT1 substrates [cytosol]
SPN [cytosol]
OCT1 transports organic cations out of hepatic cells (Drosophila melanogaster)
OCT1 substrates [cytosol]
SPN [cytosol]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Metabolism of polyamines (Gallus gallus)
Interconversion of polyamines (Gallus gallus)
Spermine => N-acetylated spermine (Gallus gallus)
SPN [cytosol]
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Gallus gallus)
SPN [cytosol]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of bile salts and organic acids, metal ions and amine compounds (Gallus gallus)
Organic cation/anion/zwitterion transport (Gallus gallus)
Organic cation transport (Gallus gallus)
OCT1 transports organic cations into hepatic cells (Gallus gallus)
OCT1 substrates [cytosol]
SPN [cytosol]
OCT1 transports organic cations out of hepatic cells (Gallus gallus)
OCT1 substrates [cytosol]
SPN [cytosol]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Metabolism of polyamines (Homo sapiens)
Interconversion of polyamines (Homo sapiens)
Spermine => N-acetylated spermine (Homo sapiens)
SPN [cytosol]
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Homo sapiens)
SPN [cytosol]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Organic cation/anion/zwitterion transport (Homo sapiens)
Organic cation transport (Homo sapiens)
OCT1 transports organic cations into hepatic cells (Homo sapiens)
OCT1 substrates [cytosol]
SPN [cytosol]
OCT1 transports organic cations out of hepatic cells (Homo sapiens)
OCT1 substrates [cytosol]
SPN [cytosol]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Metabolism of polyamines (Mus musculus)
Interconversion of polyamines (Mus musculus)
Spermine => N-acetylated spermine (Mus musculus)
SPN [cytosol]
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Mus musculus)
SPN [cytosol]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of bile salts and organic acids, metal ions and amine compounds (Mus musculus)
Organic cation/anion/zwitterion transport (Mus musculus)
Organic cation transport (Mus musculus)
OCT1 transports organic cations into hepatic cells (Mus musculus)
OCT1 substrates [cytosol]
SPN [cytosol]
OCT1 transports organic cations out of hepatic cells (Mus musculus)
OCT1 substrates [cytosol]
SPN [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Metabolism of polyamines (Rattus norvegicus)
Interconversion of polyamines (Rattus norvegicus)
Spermine => N-acetylated spermine (Rattus norvegicus)
SPN [cytosol]
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Rattus norvegicus)
SPN [cytosol]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of bile salts and organic acids, metal ions and amine compounds (Rattus norvegicus)
Organic cation/anion/zwitterion transport (Rattus norvegicus)
Organic cation transport (Rattus norvegicus)
OCT1 transports organic cations into hepatic cells (Rattus norvegicus)
OCT1 substrates [cytosol]
SPN [cytosol]
OCT1 transports organic cations out of hepatic cells (Rattus norvegicus)
OCT1 substrates [cytosol]
SPN [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Metabolism of polyamines (Saccharomyces cerevisiae)
Interconversion of polyamines (Saccharomyces cerevisiae)
Spermine => N-acetylated spermine (Saccharomyces cerevisiae)
SPN [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Metabolism of polyamines (Schizosaccharomyces pombe)
Interconversion of polyamines (Schizosaccharomyces pombe)
Spermine => N-acetylated spermine (Schizosaccharomyces pombe)
SPN [cytosol]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Metabolism of polyamines (Sus scrofa)
Interconversion of polyamines (Sus scrofa)
Spermine => N-acetylated spermine (Sus scrofa)
SPN [cytosol]
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Sus scrofa)
SPN [cytosol]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of bile salts and organic acids, metal ions and amine compounds (Sus scrofa)
Organic cation/anion/zwitterion transport (Sus scrofa)
Organic cation transport (Sus scrofa)
OCT1 transports organic cations into hepatic cells (Sus scrofa)
OCT1 substrates [cytosol]
SPN [cytosol]
OCT1 transports organic cations out of hepatic cells (Sus scrofa)
OCT1 substrates [cytosol]
SPN [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Metabolism of polyamines (Xenopus tropicalis)
Interconversion of polyamines (Xenopus tropicalis)
Spermine => N-acetylated spermine (Xenopus tropicalis)
SPN [cytosol]
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Xenopus tropicalis)
SPN [cytosol]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of bile salts and organic acids, metal ions and amine compounds (Xenopus tropicalis)
Organic cation/anion/zwitterion transport (Xenopus tropicalis)
Organic cation transport (Xenopus tropicalis)
OCT1 transports organic cations into hepatic cells (Xenopus tropicalis)
OCT1 substrates [cytosol]
SPN [cytosol]
OCT1 transports organic cations out of hepatic cells (Xenopus tropicalis)
OCT1 substrates [cytosol]
SPN [cytosol]
External Reference Information
External Reference
spermine(4+) [ChEBI:45725]
Participates
as a member of
OCT1 substrates [cytosol]
as an output of
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Drosophila melanogaster)
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Gallus gallus)
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Xenopus tropicalis)
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Danio rerio)
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Sus scrofa)
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Bos taurus)
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Canis familiaris)
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Rattus norvegicus)
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Mus musculus)
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Homo sapiens)
as an input of
Spermine => N-acetylated spermine (Saccharomyces cerevisiae)
Spermine => N-acetylated spermine (Schizosaccharomyces pombe)
Spermine => N-acetylated spermine (Dictyostelium discoideum)
Spermine => N-acetylated spermine (Caenorhabditis elegans)
Spermine => N-acetylated spermine (Drosophila melanogaster)
Spermine => N-acetylated spermine (Gallus gallus)
Spermine => N-acetylated spermine (Xenopus tropicalis)
Spermine => N-acetylated spermine (Danio rerio)
Spermine => N-acetylated spermine (Sus scrofa)
Spermine => N-acetylated spermine (Bos taurus)
Spermine => N-acetylated spermine (Canis familiaris)
Spermine => N-acetylated spermine (Rattus norvegicus)
Spermine => N-acetylated spermine (Mus musculus)
Spermine => N-acetylated spermine (Homo sapiens)
Other forms of this molecule
SPN [extracellular region]
SPN [peroxisomal matrix]
Cross References
COMPOUND
C00750
ZINC
000001532734
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