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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
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Analysis Tools
Analysis Data
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Tissue Distribution
Diseases
Cytomics
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IMP [cytosol]
Stable Identifier
R-ALL-29602
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Inosinic acid, Inosine monophosphate, Inosine 5'-monophosphate, Inosine 5'-phosphate, 5'-Inosinate, 5'-Inosinic acid, 5'-Inosine monophosphate
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Drug ADME (Bos taurus)
Abacavir ADME (Bos taurus)
Abacavir metabolism (Bos taurus)
carbovir + IMP => carbovir monophosphate + inosine (Bos taurus)
IMP [cytosol]
Ribavirin ADME (Bos taurus)
NT5C2 tetramer phosphorylates RBV (Bos taurus)
IMP [cytosol]
Metabolism (Bos taurus)
Metabolism of nucleotides (Bos taurus)
Nucleotide biosynthesis (Bos taurus)
Purine ribonucleoside monophosphate biosynthesis (Bos taurus)
FAICAR => IMP + H2O (Bos taurus)
IMP [cytosol]
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Bos taurus)
IMP [cytosol]
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Bos taurus)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Bos taurus)
IMP [cytosol]
Nucleotide catabolism (Bos taurus)
Purine catabolism (Bos taurus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Bos taurus)
(d)AMP, (d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Bos taurus)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Bos taurus)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
ITPA hydrolyses ITP to IMP (Bos taurus)
IMP [cytosol]
Nucleotide salvage (Bos taurus)
Purine salvage (Bos taurus)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Bos taurus)
IMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Bos taurus)
IMP [cytosol]
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Bos taurus)
IMP [cytosol]
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Bos taurus)
GMP, IMP [cytosol]
IMP [cytosol]
Drug ADME (Caenorhabditis elegans)
Abacavir ADME (Caenorhabditis elegans)
Abacavir metabolism (Caenorhabditis elegans)
carbovir + IMP => carbovir monophosphate + inosine (Caenorhabditis elegans)
IMP [cytosol]
Ribavirin ADME (Caenorhabditis elegans)
NT5C2 tetramer phosphorylates RBV (Caenorhabditis elegans)
IMP [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of nucleotides (Caenorhabditis elegans)
Nucleotide biosynthesis (Caenorhabditis elegans)
Purine ribonucleoside monophosphate biosynthesis (Caenorhabditis elegans)
FAICAR => IMP + H2O (Caenorhabditis elegans)
IMP [cytosol]
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Caenorhabditis elegans)
IMP [cytosol]
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Caenorhabditis elegans)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Caenorhabditis elegans)
IMP [cytosol]
Nucleotide catabolism (Caenorhabditis elegans)
Purine catabolism (Caenorhabditis elegans)
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Caenorhabditis elegans)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
ITPA hydrolyses ITP to IMP (Caenorhabditis elegans)
IMP [cytosol]
Nucleotide salvage (Caenorhabditis elegans)
Purine salvage (Caenorhabditis elegans)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Caenorhabditis elegans)
IMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Caenorhabditis elegans)
IMP [cytosol]
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Caenorhabditis elegans)
IMP [cytosol]
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Caenorhabditis elegans)
GMP, IMP [cytosol]
IMP [cytosol]
Drug ADME (Canis familiaris)
Abacavir ADME (Canis familiaris)
Abacavir metabolism (Canis familiaris)
carbovir + IMP => carbovir monophosphate + inosine (Canis familiaris)
IMP [cytosol]
Ribavirin ADME (Canis familiaris)
NT5C2 tetramer phosphorylates RBV (Canis familiaris)
IMP [cytosol]
Metabolism (Canis familiaris)
Metabolism of nucleotides (Canis familiaris)
Nucleotide biosynthesis (Canis familiaris)
Purine ribonucleoside monophosphate biosynthesis (Canis familiaris)
FAICAR => IMP + H2O (Canis familiaris)
IMP [cytosol]
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Canis familiaris)
IMP [cytosol]
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Canis familiaris)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Canis familiaris)
IMP [cytosol]
Nucleotide catabolism (Canis familiaris)
Purine catabolism (Canis familiaris)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Canis familiaris)
(d)AMP, (d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Canis familiaris)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Canis familiaris)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
ITPA hydrolyses ITP to IMP (Canis familiaris)
IMP [cytosol]
Nucleotide salvage (Canis familiaris)
Purine salvage (Canis familiaris)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Canis familiaris)
IMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Canis familiaris)
IMP [cytosol]
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Canis familiaris)
IMP [cytosol]
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Canis familiaris)
GMP, IMP [cytosol]
IMP [cytosol]
Metabolism (Danio rerio)
Metabolism of nucleotides (Danio rerio)
Nucleotide biosynthesis (Danio rerio)
Purine ribonucleoside monophosphate biosynthesis (Danio rerio)
FAICAR => IMP + H2O (Danio rerio)
IMP [cytosol]
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Danio rerio)
IMP [cytosol]
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Danio rerio)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Danio rerio)
IMP [cytosol]
Nucleotide catabolism (Danio rerio)
Purine catabolism (Danio rerio)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Danio rerio)
(d)AMP, (d)GMP, (d)IMP [cytosol]
IMP [cytosol]
ITPA hydrolyses ITP to IMP (Danio rerio)
IMP [cytosol]
Nucleotide salvage (Danio rerio)
Purine salvage (Danio rerio)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Danio rerio)
IMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Danio rerio)
IMP [cytosol]
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Danio rerio)
IMP [cytosol]
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Danio rerio)
GMP, IMP [cytosol]
IMP [cytosol]
Drug ADME (Dictyostelium discoideum)
Abacavir ADME (Dictyostelium discoideum)
Abacavir metabolism (Dictyostelium discoideum)
carbovir + IMP => carbovir monophosphate + inosine (Dictyostelium discoideum)
IMP [cytosol]
Ribavirin ADME (Dictyostelium discoideum)
NT5C2 tetramer phosphorylates RBV (Dictyostelium discoideum)
IMP [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of nucleotides (Dictyostelium discoideum)
Nucleotide biosynthesis (Dictyostelium discoideum)
Purine ribonucleoside monophosphate biosynthesis (Dictyostelium discoideum)
FAICAR => IMP + H2O (Dictyostelium discoideum)
IMP [cytosol]
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Dictyostelium discoideum)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Dictyostelium discoideum)
IMP [cytosol]
Nucleotide catabolism (Dictyostelium discoideum)
Purine catabolism (Dictyostelium discoideum)
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Dictyostelium discoideum)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
ITPA hydrolyses ITP to IMP (Dictyostelium discoideum)
IMP [cytosol]
Nucleotide salvage (Dictyostelium discoideum)
Purine salvage (Dictyostelium discoideum)
AMP + H2O => IMP + NH4+ (AMPD) (Dictyostelium discoideum)
IMP [cytosol]
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Dictyostelium discoideum)
GMP, IMP [cytosol]
IMP [cytosol]
Drug ADME (Drosophila melanogaster)
Abacavir ADME (Drosophila melanogaster)
Abacavir metabolism (Drosophila melanogaster)
carbovir + IMP => carbovir monophosphate + inosine (Drosophila melanogaster)
IMP [cytosol]
Ribavirin ADME (Drosophila melanogaster)
NT5C2 tetramer phosphorylates RBV (Drosophila melanogaster)
IMP [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of nucleotides (Drosophila melanogaster)
Nucleotide biosynthesis (Drosophila melanogaster)
Purine ribonucleoside monophosphate biosynthesis (Drosophila melanogaster)
FAICAR => IMP + H2O (Drosophila melanogaster)
IMP [cytosol]
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Drosophila melanogaster)
IMP [cytosol]
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Drosophila melanogaster)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Drosophila melanogaster)
IMP [cytosol]
Nucleotide catabolism (Drosophila melanogaster)
Purine catabolism (Drosophila melanogaster)
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Drosophila melanogaster)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
ITPA hydrolyses ITP to IMP (Drosophila melanogaster)
IMP [cytosol]
Nucleotide salvage (Drosophila melanogaster)
Purine salvage (Drosophila melanogaster)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Drosophila melanogaster)
IMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Drosophila melanogaster)
IMP [cytosol]
Drug ADME (Gallus gallus)
Abacavir ADME (Gallus gallus)
Abacavir metabolism (Gallus gallus)
carbovir + IMP => carbovir monophosphate + inosine (Gallus gallus)
IMP [cytosol]
Ribavirin ADME (Gallus gallus)
NT5C2 tetramer phosphorylates RBV (Gallus gallus)
IMP [cytosol]
Metabolism (Gallus gallus)
Nucleotide metabolism (Gallus gallus)
Purine metabolism (Gallus gallus)
De novo synthesis of AMP (Gallus gallus)
inosine 5'-monophosphate (IMP) + L-aspartate + GTP => adenylosuccinate + GDP + orthophosphate (Gallus gallus)
IMP [cytosol]
De novo synthesis of GMP (Gallus gallus)
inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ (Gallus gallus)
IMP [cytosol]
De novo synthesis of IMP (Gallus gallus)
5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) <=> inosine 5'-monophosphate + H2O (Gallus gallus)
IMP [cytosol]
Formation of PPAT dimers (Gallus gallus)
IMP [cytosol]
Urate synthesis (Gallus gallus)
inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate (Gallus gallus)
IMP [cytosol]
Drug ADME (Homo sapiens)
Abacavir ADME (Homo sapiens)
Abacavir metabolism (Homo sapiens)
carbovir + IMP => carbovir monophosphate + inosine (Homo sapiens)
IMP [cytosol]
Ribavirin ADME (Homo sapiens)
NT5C2 tetramer phosphorylates RBV (Homo sapiens)
IMP [cytosol]
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Nucleotide biosynthesis (Homo sapiens)
Purine ribonucleoside monophosphate biosynthesis (Homo sapiens)
FAICAR => IMP + H2O (Homo sapiens)
IMP [cytosol]
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Homo sapiens)
IMP [cytosol]
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Homo sapiens)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Homo sapiens)
IMP [cytosol]
Nucleotide catabolism (Homo sapiens)
Purine catabolism (Homo sapiens)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Homo sapiens)
(d)AMP, (d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Homo sapiens)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Homo sapiens)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
ITPA hydrolyses ITP to IMP (Homo sapiens)
IMP [cytosol]
Nucleotide salvage (Homo sapiens)
Purine salvage (Homo sapiens)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Homo sapiens)
IMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Homo sapiens)
IMP [cytosol]
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Homo sapiens)
IMP [cytosol]
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Homo sapiens)
GMP, IMP [cytosol]
IMP [cytosol]
Drug ADME (Mus musculus)
Abacavir ADME (Mus musculus)
Abacavir metabolism (Mus musculus)
carbovir + IMP => carbovir monophosphate + inosine (Mus musculus)
IMP [cytosol]
Ribavirin ADME (Mus musculus)
NT5C2 tetramer phosphorylates RBV (Mus musculus)
IMP [cytosol]
Metabolism (Mus musculus)
Metabolism of nucleotides (Mus musculus)
Nucleotide biosynthesis (Mus musculus)
Purine ribonucleoside monophosphate biosynthesis (Mus musculus)
FAICAR => IMP + H2O (Mus musculus)
IMP [cytosol]
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Mus musculus)
IMP [cytosol]
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Mus musculus)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Mus musculus)
IMP [cytosol]
Nucleotide catabolism (Mus musculus)
Purine catabolism (Mus musculus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Mus musculus)
(d)AMP, (d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Mus musculus)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Mus musculus)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
ITPA hydrolyses ITP to IMP (Mus musculus)
IMP [cytosol]
Nucleotide salvage (Mus musculus)
Purine salvage (Mus musculus)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Mus musculus)
IMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Mus musculus)
IMP [cytosol]
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Mus musculus)
IMP [cytosol]
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Mus musculus)
GMP, IMP [cytosol]
IMP [cytosol]
Metabolism (Plasmodium falciparum)
Metabolism of nucleotides (Plasmodium falciparum)
Nucleotide biosynthesis (Plasmodium falciparum)
Purine ribonucleoside monophosphate biosynthesis (Plasmodium falciparum)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Plasmodium falciparum)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Plasmodium falciparum)
IMP [cytosol]
Nucleotide catabolism (Plasmodium falciparum)
Purine catabolism (Plasmodium falciparum)
ITPA hydrolyses ITP to IMP (Plasmodium falciparum)
IMP [cytosol]
Nucleotide salvage (Plasmodium falciparum)
Purine salvage (Plasmodium falciparum)
AMP + H2O => IMP + NH4+ (AMPD) (Plasmodium falciparum)
IMP [cytosol]
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Plasmodium falciparum)
GMP, IMP [cytosol]
IMP [cytosol]
Drug ADME (Rattus norvegicus)
Abacavir ADME (Rattus norvegicus)
Abacavir metabolism (Rattus norvegicus)
carbovir + IMP => carbovir monophosphate + inosine (Rattus norvegicus)
IMP [cytosol]
Ribavirin ADME (Rattus norvegicus)
NT5C2 tetramer phosphorylates RBV (Rattus norvegicus)
IMP [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of nucleotides (Rattus norvegicus)
Nucleotide biosynthesis (Rattus norvegicus)
Purine ribonucleoside monophosphate biosynthesis (Rattus norvegicus)
FAICAR => IMP + H2O (Rattus norvegicus)
IMP [cytosol]
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Rattus norvegicus)
IMP [cytosol]
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Rattus norvegicus)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Rattus norvegicus)
IMP [cytosol]
Nucleotide catabolism (Rattus norvegicus)
Purine catabolism (Rattus norvegicus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Rattus norvegicus)
(d)AMP, (d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Rattus norvegicus)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Rattus norvegicus)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
ITPA hydrolyses ITP to IMP (Rattus norvegicus)
IMP [cytosol]
Nucleotide salvage (Rattus norvegicus)
Purine salvage (Rattus norvegicus)
AMP + H2O => IMP + NH4+ (AMPD) (Rattus norvegicus)
IMP [cytosol]
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Rattus norvegicus)
IMP [cytosol]
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Rattus norvegicus)
GMP, IMP [cytosol]
IMP [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of nucleotides (Saccharomyces cerevisiae)
Nucleotide biosynthesis (Saccharomyces cerevisiae)
Purine ribonucleoside monophosphate biosynthesis (Saccharomyces cerevisiae)
FAICAR => IMP + H2O (Saccharomyces cerevisiae)
IMP [cytosol]
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Saccharomyces cerevisiae)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Saccharomyces cerevisiae)
IMP [cytosol]
Nucleotide catabolism (Saccharomyces cerevisiae)
Purine catabolism (Saccharomyces cerevisiae)
ITPA hydrolyses ITP to IMP (Saccharomyces cerevisiae)
IMP [cytosol]
Nucleotide salvage (Saccharomyces cerevisiae)
Purine salvage (Saccharomyces cerevisiae)
AMP + H2O => IMP + NH4+ (AMPD) (Saccharomyces cerevisiae)
IMP [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of nucleotides (Schizosaccharomyces pombe)
Nucleotide biosynthesis (Schizosaccharomyces pombe)
Purine ribonucleoside monophosphate biosynthesis (Schizosaccharomyces pombe)
FAICAR => IMP + H2O (Schizosaccharomyces pombe)
IMP [cytosol]
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Schizosaccharomyces pombe)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Schizosaccharomyces pombe)
IMP [cytosol]
Nucleotide catabolism (Schizosaccharomyces pombe)
Purine catabolism (Schizosaccharomyces pombe)
ITPA hydrolyses ITP to IMP (Schizosaccharomyces pombe)
IMP [cytosol]
Nucleotide salvage (Schizosaccharomyces pombe)
Purine salvage (Schizosaccharomyces pombe)
AMP + H2O => IMP + NH4+ (AMPD) (Schizosaccharomyces pombe)
IMP [cytosol]
Drug ADME (Sus scrofa)
Abacavir ADME (Sus scrofa)
Abacavir metabolism (Sus scrofa)
carbovir + IMP => carbovir monophosphate + inosine (Sus scrofa)
IMP [cytosol]
Ribavirin ADME (Sus scrofa)
NT5C2 tetramer phosphorylates RBV (Sus scrofa)
IMP [cytosol]
Metabolism (Sus scrofa)
Metabolism of nucleotides (Sus scrofa)
Nucleotide biosynthesis (Sus scrofa)
Purine ribonucleoside monophosphate biosynthesis (Sus scrofa)
FAICAR => IMP + H2O (Sus scrofa)
IMP [cytosol]
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Sus scrofa)
IMP [cytosol]
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Sus scrofa)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Sus scrofa)
IMP [cytosol]
Nucleotide catabolism (Sus scrofa)
Purine catabolism (Sus scrofa)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Sus scrofa)
(d)AMP, (d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Sus scrofa)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Sus scrofa)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
ITPA hydrolyses ITP to IMP (Sus scrofa)
IMP [cytosol]
Nucleotide salvage (Sus scrofa)
Purine salvage (Sus scrofa)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Sus scrofa)
IMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Sus scrofa)
IMP [cytosol]
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Sus scrofa)
IMP [cytosol]
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Sus scrofa)
GMP, IMP [cytosol]
IMP [cytosol]
Drug ADME (Xenopus tropicalis)
Abacavir ADME (Xenopus tropicalis)
Abacavir metabolism (Xenopus tropicalis)
carbovir + IMP => carbovir monophosphate + inosine (Xenopus tropicalis)
IMP [cytosol]
Ribavirin ADME (Xenopus tropicalis)
NT5C2 tetramer phosphorylates RBV (Xenopus tropicalis)
IMP [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of nucleotides (Xenopus tropicalis)
Nucleotide biosynthesis (Xenopus tropicalis)
Purine ribonucleoside monophosphate biosynthesis (Xenopus tropicalis)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Xenopus tropicalis)
IMP [cytosol]
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Xenopus tropicalis)
IMP [cytosol]
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Xenopus tropicalis)
IMP [cytosol]
Nucleotide catabolism (Xenopus tropicalis)
Purine catabolism (Xenopus tropicalis)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Xenopus tropicalis)
(d)AMP, (d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Xenopus tropicalis)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Xenopus tropicalis)
(d)GMP, (d)IMP [cytosol]
IMP [cytosol]
ITPA hydrolyses ITP to IMP (Xenopus tropicalis)
IMP [cytosol]
Nucleotide salvage (Xenopus tropicalis)
Purine salvage (Xenopus tropicalis)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Xenopus tropicalis)
IMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Xenopus tropicalis)
IMP [cytosol]
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Xenopus tropicalis)
IMP [cytosol]
External Reference Information
External Reference
IMP(2-) [ChEBI:58053]
Participates
as an input of
inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate (Gallus gallus)
inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate (Mus musculus)
inosine 5'-monophosphate (IMP) + L-aspartate + GTP => adenylosuccinate + GDP + orthophosphate (Gallus gallus)
inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ (Gallus gallus)
NT5C2 tetramer phosphorylates RBV (Dictyostelium discoideum)
NT5C2 tetramer phosphorylates RBV (Caenorhabditis elegans)
NT5C2 tetramer phosphorylates RBV (Drosophila melanogaster)
NT5C2 tetramer phosphorylates RBV (Gallus gallus)
NT5C2 tetramer phosphorylates RBV (Xenopus tropicalis)
NT5C2 tetramer phosphorylates RBV (Sus scrofa)
NT5C2 tetramer phosphorylates RBV (Bos taurus)
NT5C2 tetramer phosphorylates RBV (Canis familiaris)
NT5C2 tetramer phosphorylates RBV (Rattus norvegicus)
NT5C2 tetramer phosphorylates RBV (Mus musculus)
NT5C2 tetramer phosphorylates RBV (Homo sapiens)
carbovir + IMP => carbovir monophosphate + inosine (Dictyostelium discoideum)
carbovir + IMP => carbovir monophosphate + inosine (Caenorhabditis elegans)
carbovir + IMP => carbovir monophosphate + inosine (Drosophila melanogaster)
carbovir + IMP => carbovir monophosphate + inosine (Gallus gallus)
carbovir + IMP => carbovir monophosphate + inosine (Xenopus tropicalis)
carbovir + IMP => carbovir monophosphate + inosine (Sus scrofa)
carbovir + IMP => carbovir monophosphate + inosine (Bos taurus)
carbovir + IMP => carbovir monophosphate + inosine (Canis familiaris)
carbovir + IMP => carbovir monophosphate + inosine (Rattus norvegicus)
carbovir + IMP => carbovir monophosphate + inosine (Mus musculus)
carbovir + IMP => carbovir monophosphate + inosine (Homo sapiens)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Homo sapiens)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Homo sapiens)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Mus musculus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Rattus norvegicus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Canis familiaris)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Bos taurus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Sus scrofa)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Danio rerio)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Xenopus tropicalis)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Gallus gallus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Drosophila melanogaster)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Caenorhabditis elegans)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Dictyostelium discoideum)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Schizosaccharomyces pombe)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Saccharomyces cerevisiae)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Plasmodium falciparum)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Mus musculus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Rattus norvegicus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Canis familiaris)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Bos taurus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Sus scrofa)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Xenopus tropicalis)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Gallus gallus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Drosophila melanogaster)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Caenorhabditis elegans)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Danio rerio)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Dictyostelium discoideum)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Schizosaccharomyces pombe)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Saccharomyces cerevisiae)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Plasmodium falciparum)
as an output of
5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) <=> inosine 5'-monophosphate + H2O (Gallus gallus)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Caenorhabditis elegans)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Xenopus tropicalis)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Danio rerio)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Sus scrofa)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Bos taurus)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Canis familiaris)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Rattus norvegicus)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Mus musculus)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Homo sapiens)
GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Gallus gallus)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Caenorhabditis elegans)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Drosophila melanogaster)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Xenopus tropicalis)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Danio rerio)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Sus scrofa)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Bos taurus)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Canis familiaris)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Mus musculus)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Homo sapiens)
ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Gallus gallus)
ITPA hydrolyses ITP to IMP (Plasmodium falciparum)
ITPA hydrolyses ITP to IMP (Saccharomyces cerevisiae)
ITPA hydrolyses ITP to IMP (Schizosaccharomyces pombe)
ITPA hydrolyses ITP to IMP (Dictyostelium discoideum)
ITPA hydrolyses ITP to IMP (Caenorhabditis elegans)
ITPA hydrolyses ITP to IMP (Drosophila melanogaster)
ITPA hydrolyses ITP to IMP (Xenopus tropicalis)
ITPA hydrolyses ITP to IMP (Danio rerio)
ITPA hydrolyses ITP to IMP (Sus scrofa)
ITPA hydrolyses ITP to IMP (Bos taurus)
ITPA hydrolyses ITP to IMP (Canis familiaris)
ITPA hydrolyses ITP to IMP (Rattus norvegicus)
ITPA hydrolyses ITP to IMP (Mus musculus)
ITPA hydrolyses ITP to IMP (Homo sapiens)
ITPA hydrolyses ITP to IMP (Gallus gallus)
AMP + H2O => IMP + NH4+ (AMPD) (Plasmodium falciparum)
AMP + H2O => IMP + NH4+ (AMPD) (Saccharomyces cerevisiae)
AMP + H2O => IMP + NH4+ (AMPD) (Schizosaccharomyces pombe)
AMP + H2O => IMP + NH4+ (AMPD) (Dictyostelium discoideum)
AMP + H2O => IMP + NH4+ (AMPD) (Caenorhabditis elegans)
AMP + H2O => IMP + NH4+ (AMPD) (Drosophila melanogaster)
AMP + H2O => IMP + NH4+ (AMPD) (Gallus gallus)
AMP + H2O => IMP + NH4+ (AMPD) (Xenopus tropicalis)
AMP + H2O => IMP + NH4+ (AMPD) (Danio rerio)
AMP + H2O => IMP + NH4+ (AMPD) (Sus scrofa)
AMP + H2O => IMP + NH4+ (AMPD) (Bos taurus)
AMP + H2O => IMP + NH4+ (AMPD) (Canis familiaris)
AMP + H2O => IMP + NH4+ (AMPD) (Rattus norvegicus)
AMP + H2O => IMP + NH4+ (AMPD) (Mus musculus)
AMP + H2O => IMP + NH4+ (AMPD) (Homo sapiens)
FAICAR => IMP + H2O (Homo sapiens)
FAICAR => IMP + H2O (Mus musculus)
FAICAR => IMP + H2O (Rattus norvegicus)
FAICAR => IMP + H2O (Canis familiaris)
FAICAR => IMP + H2O (Bos taurus)
FAICAR => IMP + H2O (Sus scrofa)
FAICAR => IMP + H2O (Danio rerio)
FAICAR => IMP + H2O (Gallus gallus)
FAICAR => IMP + H2O (Drosophila melanogaster)
FAICAR => IMP + H2O (Caenorhabditis elegans)
FAICAR => IMP + H2O (Dictyostelium discoideum)
FAICAR => IMP + H2O (Schizosaccharomyces pombe)
FAICAR => IMP + H2O (Saccharomyces cerevisiae)
as a member of
(d)AMP, (d)GMP, (d)IMP [cytosol]
GMP, IMP [cytosol]
(d)GMP, (d)IMP [cytosol]
This entity regulates
Negatively
Formation of PPAT dimers
(Gallus gallus)
Positively
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Caenorhabditis elegans)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Drosophila melanogaster)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Gallus gallus)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Xenopus tropicalis)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Danio rerio)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Sus scrofa)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Bos taurus)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Canis familiaris)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Rattus norvegicus)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Mus musculus)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Homo sapiens)
Other forms of this molecule
IMP [extracellular region]
IMP [nucleoplasm]
IMP [extracellular region]
Cross References
COMPOUND
C00130
ZINC
000004228242
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