Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
MVA [cytosol]
Stable Identifier
R-ALL-191424
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Mevalonate, (R)-mevalonic acid
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of lipids (Bos taurus)
Metabolism of steroids (Bos taurus)
Cholesterol biosynthesis (Bos taurus)
HMGCR dimer reduces bHMG-CoA to MVA (Bos taurus)
MVA [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Bos taurus)
MVA [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of lipids (Caenorhabditis elegans)
Metabolism of steroids (Caenorhabditis elegans)
Cholesterol biosynthesis (Caenorhabditis elegans)
HMGCR dimer reduces bHMG-CoA to MVA (Caenorhabditis elegans)
MVA [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Caenorhabditis elegans)
MVA [cytosol]
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Metabolism of steroids (Canis familiaris)
Cholesterol biosynthesis (Canis familiaris)
HMGCR dimer reduces bHMG-CoA to MVA (Canis familiaris)
MVA [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Canis familiaris)
MVA [cytosol]
Metabolism (Danio rerio)
Metabolism of lipids (Danio rerio)
Metabolism of steroids (Danio rerio)
Cholesterol biosynthesis (Danio rerio)
HMGCR dimer reduces bHMG-CoA to MVA (Danio rerio)
MVA [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Danio rerio)
MVA [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of lipids (Dictyostelium discoideum)
Metabolism of steroids (Dictyostelium discoideum)
Cholesterol biosynthesis (Dictyostelium discoideum)
HMGCR dimer reduces bHMG-CoA to MVA (Dictyostelium discoideum)
MVA [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Dictyostelium discoideum)
MVA [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Metabolism of steroids (Drosophila melanogaster)
Cholesterol biosynthesis (Drosophila melanogaster)
HMGCR dimer reduces bHMG-CoA to MVA (Drosophila melanogaster)
MVA [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Drosophila melanogaster)
MVA [cytosol]
Metabolism (Gallus gallus)
Metabolism of lipids (Gallus gallus)
Metabolism of steroids (Gallus gallus)
Cholesterol biosynthesis (Gallus gallus)
HMGCR dimer reduces bHMG-CoA to MVA (Gallus gallus)
MVA [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Gallus gallus)
MVA [cytosol]
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Cholesterol biosynthesis (Homo sapiens)
HMGCR dimer reduces bHMG-CoA to MVA (Homo sapiens)
MVA [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Homo sapiens)
MVA [cytosol]
Metabolism (Mus musculus)
Metabolism of lipids (Mus musculus)
Metabolism of steroids (Mus musculus)
Cholesterol biosynthesis (Mus musculus)
HMGCR dimer reduces bHMG-CoA to MVA (Mus musculus)
MVA [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Mus musculus)
MVA [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Cholesterol biosynthesis (Rattus norvegicus)
HMGCR dimer reduces bHMG-CoA to MVA (Rattus norvegicus)
MVA [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Rattus norvegicus)
MVA [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of lipids (Saccharomyces cerevisiae)
Metabolism of steroids (Saccharomyces cerevisiae)
Cholesterol biosynthesis (Saccharomyces cerevisiae)
HMGCR dimer reduces bHMG-CoA to MVA (Saccharomyces cerevisiae)
MVA [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Saccharomyces cerevisiae)
MVA [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of lipids (Schizosaccharomyces pombe)
Metabolism of steroids (Schizosaccharomyces pombe)
Cholesterol biosynthesis (Schizosaccharomyces pombe)
HMGCR dimer reduces bHMG-CoA to MVA (Schizosaccharomyces pombe)
MVA [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Schizosaccharomyces pombe)
MVA [cytosol]
Metabolism (Sus scrofa)
Metabolism of lipids (Sus scrofa)
Metabolism of steroids (Sus scrofa)
Cholesterol biosynthesis (Sus scrofa)
HMGCR dimer reduces bHMG-CoA to MVA (Sus scrofa)
MVA [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Sus scrofa)
MVA [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Metabolism of steroids (Xenopus tropicalis)
Cholesterol biosynthesis (Xenopus tropicalis)
HMGCR dimer reduces bHMG-CoA to MVA (Xenopus tropicalis)
MVA [cytosol]
External Reference Information
External Reference
(R)-mevalonate [ChEBI:36464]
Participates
as an input of
Mevalonate is phosphorylated to mevalonate-5-phosphate (Saccharomyces cerevisiae)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Schizosaccharomyces pombe)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Dictyostelium discoideum)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Caenorhabditis elegans)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Drosophila melanogaster)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Gallus gallus)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Danio rerio)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Sus scrofa)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Bos taurus)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Canis familiaris)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Rattus norvegicus)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Mus musculus)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Homo sapiens)
as an output of
HMGCR dimer reduces bHMG-CoA to MVA (Saccharomyces cerevisiae)
HMGCR dimer reduces bHMG-CoA to MVA (Schizosaccharomyces pombe)
HMGCR dimer reduces bHMG-CoA to MVA (Dictyostelium discoideum)
HMGCR dimer reduces bHMG-CoA to MVA (Caenorhabditis elegans)
HMGCR dimer reduces bHMG-CoA to MVA (Drosophila melanogaster)
HMGCR dimer reduces bHMG-CoA to MVA (Gallus gallus)
HMGCR dimer reduces bHMG-CoA to MVA (Xenopus tropicalis)
HMGCR dimer reduces bHMG-CoA to MVA (Danio rerio)
HMGCR dimer reduces bHMG-CoA to MVA (Sus scrofa)
HMGCR dimer reduces bHMG-CoA to MVA (Bos taurus)
HMGCR dimer reduces bHMG-CoA to MVA (Canis familiaris)
HMGCR dimer reduces bHMG-CoA to MVA (Rattus norvegicus)
HMGCR dimer reduces bHMG-CoA to MVA (Mus musculus)
HMGCR dimer reduces bHMG-CoA to MVA (Homo sapiens)
Cross References
Guide to Pharmacology - Ligands
3042
AraCyc
MEVALONATE
COMPOUND
C00418
PubChem Compound
5288798
ZINC
ZINC000000895221
KEGG Gene
C00418
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
