The following table contains the known resources that have integrated Reactome by using the Analysis Service, the Graph Database or any of our widgets (diagram or pathways overview). If your resource is using our services, widgets or content and it is not in the list, please This email address is being protected from spambots. You need JavaScript enabled to view it. and we will add it.

For biomedical researchers who need to identify a biological target for a new therapy, Open Targets is a public-private initiative to generate evidence on the validity of therapeutic targets based on genome-scale experiments and analysis.

Analysis Service
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Graph Database

Open Targets

Contains information for a large majority of all human protein-coding genes regarding the expression and localization of the corresponding proteins based on both RNA and protein data.

Analysis Service
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Graph Database

The Human Protein Atlas

Ensembl is a genome browser for vertebrate genomes that supports research in comparative genomics, evolution, sequence variation and transcriptional regulation. Ensembl annotate genes, computes multiple alignments, predicts regulatory function and collects disease data.

Analysis Service
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Graph Database

Ensembl

The BLUEPRINT consortium has been formed with the aim to further the understanding of how genes are activated or repressed in both healthy and diseased human cells.

Analysis Service
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Graph Database

BLUEPRINT

The Complex Portal is a manually curated, encyclopaedic resource of macromolecular complexes from a number of key model organisms. The majority of complexes are made up of proteins but may also include nucleic acids or small molecules.

Content Service
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Graph Database

Complex Portal

Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on ‘small’ chemical compounds. The term ‘molecular entity’ refers to any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer, etc., identifiable as a separately distinguishable entity.

Analysis Service
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ChEBI

PRoteomics IDEntifications (PRIDE) database is a centralized, standards compliant, public data repository for proteomics data, including protein and peptide identifications, post-translational modifications and supporting spectral evidence.

Analysis Service
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Graph Database

PRIDE

Tabloid Proteome is a database of protein association network generated using publicly available mass spectrometry based experiments in PRIDE. These associations represent a broad range of biological associations between pairs of proteins that goes well beyond mere binary protein interactions.

Analysis Service
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Graph Database

Tabloid Proteome

Integrative LINCS is an integrative web platform for analysis of LINCS data and signatures.The BD2K-LINCS Data Coordination and Integration Center is part of the Big Data to Knowledge (BD2K) NIH initiative.

Analysis Service
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iLINCS

Target-Pathogen database is a bioinformatic approach to prioritize and identify candidates drug targets for pathogens. Designed and developed as an online resource to allow genome wide data consolidation from diverse sources focusing on structural druggability, essentiality and metabolic role of proteins.

Analysis Service
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Graph Database

Target-Pathogen

BioModels is a repository of mathematical models of biological and biomedical systems. It hosts a vast selection of existing literature-based physiologically and pharmaceutically relevant mechanistic models in standard formats. Our mission is to provide the systems modelling community with reproducible, high-quality, freely-accessible models published in the scientific literature.

Analysis Service
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Graph Database

BioModels

Pharos is the user interface to the Knowledge Management Center (KMC) for the Illuminating the Druggable Genome (IDG) program.

Analysis Service
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Graph Database

PHAROS

UniProt has developed the Alzheimer’s disease portal to help researchers explore and access current AD genomic-based data from the UniProtKB database.

Analysis Service
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Graph Database

UniProt

SimpliFi is an online, browser-accessible platform that translates omics data into biological understanding. Users of all skill levels can explore and visualize their data to understand a biological state and form hypotheses. SimpliFi accepts and integrates data into clean, interactive displays of enriched differentially expressed pathways, GO enrichments, cellular markers, protein-protein interaction networks and molecular-level classifications.

Analysis Service
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Graph Database

SimpliFi

A consortium of 7 model organism databases (MODs) and the Gene Ontology (GO) Consortium whose goal is to provide an integrated view of their data to all biologists, clinicians and other interested parties.

Analysis Service
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Graph Database

Alliance of Genome Resources

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