To cite the use of Reactome in your work, please reference one or more of the following publications:

  • Jassal B, Matthews L, Viteri G, Gong C, Lorente P, Fabregat A, Sidiropoulos K, Cook J, Gillespie M, Haw R, Loney F, May B, Milacic M, Rothfels K, Sevilla C, Shamovsky V, Shorser S, Varusai T, Weiser J, Wu G, Stein L, Hermjakob H, D'Eustachio P. The reactome pathway knowledgebase. Nucleic Acids Res. 2020 Jan 8;48(D1):D498-D503. doi: 10.1093/nar/gkz1031. PubMed PMID: 31691815.
  • Fabregat A, Korninger F, Viteri G, Sidiropoulos K, Marin-Garcia P, Ping P, Wu G, Stein L, D'Eustachio P, Hermjakob H. Reactome graph database: Efficient accessto complex pathway data. PLoS Comput Biol. 2018 Jan 29;14(1):e1005968. doi: 10.1371/journal.pcbi.1005968. eCollection 2018 Jan. PubMed PMID: 29377902.
  • Fabregat A, Sidiropoulos K, Viteri G, Marin-Garcia P, Ping P, Stein L, D'Eustachio P, Hermjakob H. Reactome diagram viewer: data structures and strategies to boost performance. Bioinformatics. 2018 Apr 1;34(7):1208-1214. doi: 10.1093/bioinformatics/btx752. PubMed PMID: 29186351.
  • Sidiropoulos K, Viteri G, Sevilla C, Jupe S, Webber M, Orlic-Milacic M, Jassal B, May B, Shamovsky V, Duenas C, Rothfels K, Matthews L, Song H, Stein L, Haw R, D'Eustachio P, Ping P, Hermjakob H, Fabregat A. Reactome enhanced pathway visualization. Bioinformatics. 2017 Nov 1;33(21):3461-3467. doi: 10.1093/bioinformatics/btx441. PubMed PMID: 29077811.
  • Fabregat A, Sidiropoulos K, Viteri G, Forner O, Marin-Garcia P, Arnau V, D'Eustachio P, Stein L, Hermjakob H. Reactome pathway analysis: a high-performance in-memory approach. BMC Bioinformatics. 2017 Mar 2;18(1):142. doi: 10.1186/s12859-017-1559-2. PubMed PMID: 28249561.
  • Wu G, Haw R. Functional Interaction Network Construction and Analysis for Disease Discovery. Methods Mol Biol. 2017;1558:235-253. doi: 10.1007/978-1-4939-6783-4_11. PubMed PMID: 28150241

To cite a pathway. 

Please use the appropriate DOI from the Table of Contents within the citation, when it is available. Otherwise, use the stable identifier of the pathway. You can add a DOI to the end of your citation following the appropriate style. Generally, these citations follow this format: Author, A. (year). “Title of pathway". Reactome, release#, URL with doi:xxxxxx (date of access). If a DOI is unavailable, please follow this format: “Title of pathway". Reactome, release#, URL with StableID: R-HSA-xxxxxx.x (date of access).

Please find other citing styles at APA Style: Purdue U Online Writing Lab.

To reference an image.

Please use the appropriate DOI associated with the image from the Table of Contents within the citation, when it is available. Otherwise, use the stable identifier of the pathway associated with the image. You can add a DOI to the end of your citation following the appropriate style. Generally, these citations follow this format:  Image for “Title of pathway". Reactome, release#, URL with doi:xxxxxx (date of access). If a DOI is unavailable, please follow this format: Image for “Title of pathway". Reactome, release#, URL with StableID: R-HSA-xxxxxx.x (date of access).

To cite our files available for download.

Please use the following format: "Name of file", Reactome, release#, https://reactome.org/download-data/ (date of access).

When citing information obtained in a search.

It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available.