Since our inception, we have been an open source and open access resource,  free for use by anyone under the terms of a Creative Commons Attribution 4.0 International (CC BY 4.0) license. This license granted parties the non-exclusive right to use, distribute and create derivative works based on Reactome, provided that the works are correctly attributed to OICR, NYUMC, EBI, and OHSU.

In line with the growing movement to provide free open data in the public domain, and to better support the needs of our user community, we are updating the licensing agreement for some of our web content and data to reflect the Creative Commons Public Domain (CC0). CC0 is the "no copyright reserved" option in the Creative Commons toolkit. It effectively means relinquishing all copyright and similar rights that we hold in a work and dedicating those rights to the public domain.

A Creative Commons Public Domain (CC0 1.0 Universal) Licence will now cover all Reactome annotation files, e.g. identifier mapping, specialized data files, and interaction data derived from Reactome.

A Creative Commons Attribution 4.0 International (CC BY 4.0) Licence will continue to apply to all software and code, e.g. relating to the functionality of the reactome.org, derived websites and webservices, the Curator Tool, the Functional Interaction application, SQL and Graph Database data dumps, and Pathway Illustrations (Enhanced High-Level Diagrams), Icon Library, Art and Branding Materials.

For information about how to properly credit data use, please review the Reactome License and the Creative Commons FAQ, or contact the This email address is being protected from spambots. You need JavaScript enabled to view it..