Reactome: A Curated Pathway Database

Updated Molecular Interaction Overlay feature now available.

EGFR_MIO

As part of our efforts to give our user community better experience, we have redesigned the Molecular Interaction Overlay to support quicker, easier, and more responsive access to protein-protein and protein-small molecule interaction data within the Reactome Pathway Browser.

New features and improvements include:

  • Diagram search feature includes the gene name and chemical name for interactors.
  • Interactors display name is now the gene name for proteins and the chemical name for the chemicals.
  • Tooltips are shown when hovering over the for interaction links.
  • Interactions include links to entities present in the diagram.
  • Loop-link is included when a protein/chemical interacts with itself.
  • Display option to show/hide interactors based upon a selected weighted score.
  • Crystal and chemical structures for the interactors are displayed at zoomed-in view.
  • Diagram image export for the zoomed-in view includes the protein structures in the final image.
  • Interactor file download is now available in both the Interactors toolbar and Settings panel.

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