Reactome: A Curated Pathway Database
ABL1
ABL1
Description: Tyrosine-protein kinase ABL1

Curator: Bruce May
AC
AC
Description: Adenylate cyclase family

Curator: Steve Jupe
ACT1
ACT1
Description: Ankyrin-1

Curator: Steve Jupe
actin
actin
Description: Actin is a family of globular multi-functional proteins that form microfilaments

Curator: Steve Jupe
aggregated protein
aggregated protein
Description: Aggregated protein

AGO2
AGO2
Description: Protein argonaute-2

Curator: Bruce May
AKT
AKT
Description: RAC-alpha serine/threonine-protein kinase

ANK 1 2 3
ANK 1 2 3
Description: ANK1, 2, 3

Curator: Steve Jupe
antibody
antibody
Description: Antibody

Curator: Steve Jupe
ASPPs
ASPPs
Description: Apoptosis-stimulating of p53 protein 2

ATM
ATM
Description: Serine-protein kinase ATM

ATR
ATR
Description: Serine/threonine-protein kinase ATR

B4GALT1
B4GALT1
Description: Beta-1,4-galactosyltransferase 1

BIRC2-3
BIRC2-3
Description: Baculoviral IAP repeat-containing protein 2 and 3

Curator: Steve Jupe
BNIP2
BNIP2
Description: BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

Curator: Bruce May
BRAF
BRAF
Description: Serine/threonine-protein kinase B-raf

Curator: Steve Jupe
BTNL
BTNL
Description: Butyrophilin-like protein

Curator: Steve Jupe
C3b
C3b
Description: Complement C3b

Curator: Steve Jupe
C5
C5
Description: Complement C5

Curator: Steve Jupe
C5a
C5a
Description: Complement C5a

Curator: Steve Jupe
C5b
C5b
Description: Complement C5b

Curator: Steve Jupe
CA4
CA4
Description: Carbonic anhydrase 4

Curator: Steve Jupe
CALDAG GEFs
CALDAG GEFs
Description: Calcium- and diacylglycerol-regulated nucleotide exchange factor

Curator: Steve Jupe
CALM1
CALM1
Description: Calmodulin

Curator: Steve Jupe
CARD
CARD
Description: Caspase activation and recruitment domain

Curator: Steve Jupe
CASK
CASK
Description: Peripheral plasma membrane protein CASK

Curator: Steve Jupe
CASPASE
CASPASE
Description: Caspases are a family of protease enzymes playing essential roles in programmed cell death and inflammation

CASPASE 3
CASPASE 3
Description: Caspases are a family of protease enzymes playing essential roles in programmed cell death and inflammation

CASPASE 8
CASPASE 8
Description: Caspases are a family of protease enzymes playing essential roles in programmed cell death and inflammation

CASPASE 9
CASPASE 9
Description: Caspases are a family of protease enzymes playing essential roles in programmed cell death and inflammation

caveolin
caveolin
Description: Caveolins are a family of integral membrane proteins that are the principal components of caveolae membranes and involved in receptor-independent endocytosis

Curator: Steve Jupe
CD47
CD47
Description: Leukocyte surface antigen CD47

Curator: Steve Jupe
CDC2AP
CDC2AP
Description: CDC2AP

Curator: Steve Jupe
CDC42
CDC42
Description: Cell division control protein 42 homolog

Curator: Steve Jupe
CHEK1
CHEK1
Description: Serine/threonine-protein kinase Chk1

CHEK2
CHEK2
Description: Serine/threonine-protein kinase Chk2

clathrin coated pit
clathrin coated pit
Description: Clathrin is a protein that plays a major role in the formation of coated vesicles. Coated pits are regions of the cell membrane specialized in receptor-mediated endocytosis. Their cytoplasmic surface is coated with a bristlelike structure made of clathrin. During the first steps of endocytosis, clathrin-coated pits are internalized to form clathrin-coated vesicles which transport proteins from organelle to organelle.

Curator: Steve Jupe
CRKL
CRKL
Description: Crk-like protein

Curator: Corina Duenas
DAPK
DAPK
Description: Death-associated protein kinase 1

DDX58
DDX58
Description: Probable ATP-dependent RNA helicase

Curator: Steve Jupe
DIP13A
DIP13A
Description: DCC-interacting protein 13-alpha

DLGs
DLGs
Description: Disks large homologs

Curator: Steve Jupe
EFHA
EFHA
Description: Ephrin type A receptor family

Curator: Steve Jupe
EFHB
EFHB
Description: Ephrin type B receptor family

Curator: Steve Jupe
EFNA
EFNA
Description: Ephrin A family

Curator: Steve Jupe
EFNB
EFNB
Description: Ephrin B family

Curator: Steve Jupe
EP300
EP300
Description: Histone acetyltransferase p300

ERKs
ERKs
Description: Mitogen-activated protein kinase 1 and 3

Curator: Steve Jupe
ESCRTs
ESCRTs
Description: Tumor susceptibility gene 101 protein

Curator: Steve Jupe
FADD
FADD
Description: FAS-associated death domain protein

FAK
FAK
Description: Focal adhesion kinase 1

Curator: Steve Jupe
FARP2
FARP2
Description: FERM, RhoGEF and pleckstrin domain-containing protein 2

Curator: Steve Jupe
ferritin
ferritin
Description: Ferritin is a universal intracellular protein that stores iron and releases it in a controlled fashion

Curator: Steve Jupe
FES
FES
Description: Tyrosine-protein kinase Fes/Fps

Curator: Steve Jupe
FGFR1
FGFR1
Description: Fibroblast growth factor receptor 1

Curator: Steve Jupe
FIBRIN
FIBRIN
Description: Fibrin clot

Curator: Steve Jupe
fibrinogen
fibrinogen
Description: Fibrinogen alpha chain

Curator: Steve Jupe
FKPB4
FKPB4
Description: FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase

FOXA2
FOXA2
Description: Hepatocyte nuclear factor 3-beta

Curator: Bruce May
FRINGE
FRINGE
Description: Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe

FURIN
FURIN
Description: Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif

FYN
FYN
Description: Tyrosine-protein kinase Fyn

Curator: Steve Jupe
FZD
FZD
Description: Frizzled-1

GAPs
GAPs
Description: Gap junction alpha-1 proteins

Curator: Steve Jupe
GDNF
GDNF
Description: Glial cell line-derived neurotrophic factor

Curator: Steve Jupe
GEFs
GEFs
Description: Gamma-aminobutyric acid receptor-associated protein-like 2

Curator: Steve Jupe
GKAP
GKAP
Description: G kinase-anchoring protein 1

Curator: Steve Jupe
GRB2
GRB2
Description: Growth factor receptor-bound protein 2

Curator: Steve Jupe
growth hormone
growth hormone
Description: Growth hormone

Curator: Steve Jupe
hemoglobin
hemoglobin
Description: Hemoglobin subunit beta

Curator: Steve Jupe
HIF1A
HIF1A
Description: Hypoxia-inducible factor 1-alpha

HIPK2
HIPK2
Description: Cellular tumor antigen p53

histone octamer 1
histone octamer 1
Description: Histone octamer

histone octamer 2
histone octamer 2
Description: Histone octamer

HMOX
HMOX
Description: Heme oxygenase 1

Curator: Steve Jupe
HOMER
HOMER
Description: Homer protein homolog 1

Curator: Steve Jupe
HSF1
HSF1
Description: Heat shock factor protein 1

HSP90
HSP90
Description: Heat shock protein HSP 90

HSPA5
HSPA5
Description: I78 kDa glucose-regulated protein

Curator: Bruce May
HSPs
HSPs
Description: Heat shock proteins are a family of proteins that are produced by cells in response to exposure to stressful conditions

IFI16
IFI16
Description: Gamma-interferon-inducible protein 16

Curator: Steve Jupe
IGF1
IGF1
Description: Insulin-like growth factor I

Curator: Bruce May
IGFBP4
IGFBP4
Description: Insulin-like growth factor-binding protein 4

Curator: Bruce May
IKK
IKK
Description: Inhibitor of nuclear factor kappa-B kinase subunit epsilon

Curator: Steve Jupe
IL-1B
IL-1B
Description: Interleukin-1B

Curator: Steve Jupe
IL-2
IL-2
Description: Interleukin-2

Curator: Steve Jupe
IL-3
IL-3
Description: Interleukin-3

Curator: Steve Jupe
IL-4
IL-4
Description: Interleukin-4

Curator: Steve Jupe
IL-6
IL-6
Description: Interleukin-6

Curator: Steve Jupe
IL-7
IL-7
Description: Interleukin-7

Curator: Steve Jupe
IL-10
IL-10
Description: Interleukin-10

Curator: Steve Jupe
IL-12
IL-12
Description: Interleukin-12

Curator: Steve Jupe
IL-13
IL-13
Description: Interleukin-13

Curator: Steve Jupe
IL-17
IL-17
Description: Interleukin-17

Curator: Steve Jupe
IL-20
IL-20
Description: Interleukin-20

Curator: Steve Jupe
IL1RAP
IL1RAP
Description: Interleukin-1 receptor accessory protein

Curator: Steve Jupe
IL1RAPL1
IL1RAPL1
Description: Interleukin-1 receptor accessory protein-like 1

Curator: Steve Jupe
IL generic
IL generic
Description: Interleukin family

Curator: Steve Jupe
INSIG
INSIG
Description: Insulin-induced gene 1 protein

insulin
insulin
Description: Insulin is a peptide hormone produced by beta cells of the pancreatic islets. It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of, especially, glucose from the blood into fat, liver and skeletal muscle cells

Curator: Bruce May
interferon
interferon
Description: Interferons

Curator: Steve Jupe
IRAK 1 2 4
IRAK 1 2 4
Description: Interleukin-1 receptor-associated kinases 1, 2 and 4

Curator: Steve Jupe
IRS
IRS
Description: Insulin receptor substrate 1

Curator: Steve Jupe
ISG15
ISG15
Description: Ubiquitin-like protein ISG15

Curator: Steve Jupe
JAK1
JAK1
Description: Tyrosine-protein kinase JAK1

Curator: Steve Jupe
JAK2
JAK2
Description: Tyrosine-protein kinase JAK2

Curator: Steve Jupe
JAK3
JAK3
Description: Tyrosine-protein kinase JAK3

Curator: Steve Jupe
JAK generic
JAK generic
Description: Janus kinase family

Curator: Steve Jupe
KALRN
KALRN
Description: Kalirin

Curator: Steve Jupe
KAT6A
KAT6A
Description: Histone acetyltransferase KAT6A

keratin monomer
keratin monomer
Description: Keratin monomer

Curator: Bruce May
L1CAM
L1CAM
Description: Neural cell adhesion molecule L1

Curator: Steve Jupe
LARG
LARG
Description: Rho guanine nucleotide exchange factor 12

Curator: Steve Jupe
LATS
LATS
Description: Serine/threonine-protein kinase LATS1

LCK
LCK
Description: Tyrosine-protein kinase Lck

Curator: Steve Jupe
LCP2
LCP2
Description: Lymphocyte cytosolic protein 2

Curator: Steve Jupe
LIMK
LIMK
Description: LIM domain kinase 1

Curator: Steve Jupe
LRP
LRP
Description: Prolow-density lipoprotein receptor-related protein 1

LRR
LRR
Description: Leucine-rich repeat

Curator: Steve Jupe
LRRTM
LRRTM
Description: Leucine-rich repeat transmembrane neuronal protein 1

Curator: Steve Jupe
LYN
LYN
Description: Tyrosine-protein kinase Lyn

Curator: Steve Jupe
MAC
MAC
Description: Membrane attack complex

Curator: Steve Jupe
MAFA
MAFA
Description: Transcription factor MafA

Curator: Bruce May
MAPK3K14
MAPK3K14
Description: Mitogen-activated protein kinase kinase kinase 14

Curator: Steve Jupe
MAPKAPK5
MAPKAPK5
Description: Cellular tumor antigen p53

MAPK 1 3
MAPK 1 3
Description: Mitogen-activated protein kinase 1 and 3

Curator: Steve Jupe
MAVS
MAVS
Description: Mitochondrial antiviral-signaling protein

Curator: Steve Jupe
Mb
Mb
Description: Myoglobin is an iron- and oxygen-binding protein

Curator: Steve Jupe
MB21D1
MB21D1
Description: Cyclic GMP-AMP synthase

Curator: Steve Jupe
MDM2
MDM2
Description: E3 ubiquitin-protein ligase Mdm2

MEKs
MEKs
Description: Dual specificity mitogen-activated protein kinase kinase 1 and 2

Curator: Steve Jupe
MICA
MICA
Description: MHC class I polypeptide-related sequence A

Curator: Steve Jupe
MKK6
MKK6
Description: Dual specificity mitogen-activated protein kinase kinase 6

Curator: Steve Jupe
MLCP
MLCP
Description: Myosin light-chain phosphatase, or myosin phosphatase, is an enzyme (specifically a serine/threonine-specific protein phosphatase) that dephosphorylates the regulatory light chain of myosin II

Curator: Steve Jupe
MOB
MOB
Description: MOB kinase activator 1A

MT1 2
MT1 2
Description: Metallothionein 1 and 2

MTF1
MTF1
Description: Metal regulatory transcription factor 1

mTOR
mTOR
Description: Serine/threonine-protein kinase mTOR

MYD88
MYD88
Description: Myeloid differentiation primary response protein MyD88

Curator: Steve Jupe
MYLK
MYLK
Description: Myosin light chain kinase, smooth muscle

Curator: Steve Jupe
N-Ras
N-Ras
Description: GTPase NRas

Curator: Steve Jupe
N-WASP
N-WASP
Description: Neural Wiskott-Aldrich syndrome protein

Curator: Steve Jupe
NANOG
NANOG
Description: Homeobox protein NANOG

Curator: Bruce May
NBD
NBD
Description: Nucleotide-binding domain

Curator: Steve Jupe
NCAM cis
NCAM cis
Description: Neural cell adhesion molecules in cis-binding

Curator: Steve Jupe
NCAM trans
NCAM trans
Description: Neural cell adhesion molecules in trans-binding

Curator: Steve Jupe
NCK1
NCK1
Description: Cytoplasmic protein NCK1

Curator: Steve Jupe
NEPH1
NEPH1
Description: Kin of IRRE-like protein 1

Curator: Steve Jupe
NEPHS1
NEPHS1
Description: NEPHS1

Curator: Steve Jupe
NEUROD1
NEUROD1
Description: Neurogenic differentiation factor 1

Curator: Bruce May
NEUROG3
NEUROG3
Description: Neurogenin-3

Curator: Bruce May
NFkappaB
NFkappaB
Description: Nuclear factor NF-kappa-B

Curator: Steve Jupe
NGEF
NGEF
Description: Ephexin-1

Curator: Steve Jupe
NKX2-2
NKX2-2
Description: Homeobox protein Nkx-2.2

Curator: Bruce May
NKX6-1
NKX6-1
Description: Homeobox protein Nkx-6.1

Curator: Bruce May
NLGN
NLGN
Description: Neuroligins

Curator: Steve Jupe
NODAL
NODAL
Description: Nodal homolog

Curator: Bruce May
NOTCH1
NOTCH1
Description: Neurogenic locus notch homolog protein 1

NOTCH2
NOTCH2
Description: Neurogenic locus notch homolog protein 2

NOTCH3
NOTCH3
Description: Neurogenic locus notch homolog protein 3

NOTCH4
NOTCH4
Description: Neurogenic locus notch homolog protein 4

NRP1 PLEXIN-A
NRP1 PLEXIN-A
Description: Neuropilin-1 and Plexin-A family

Curator: Steve Jupe
NRXN
NRXN
Description: Neurexins

Curator: Steve Jupe
NTN1
NTN1
Description: Netrin-1

Curator: Steve Jupe
NTRK3
NTRK3
Description: NT-3 growth factor receptor

Curator: Steve Jupe
OCT4
OCT4
Description: Octamer-binding transcription factor 4 also known as Aggeliki (POU domain, class 5, transcription factor 1) is a protein that in humans is encoded by the POU5F1 gene

Curator: Bruce May
oncogenic RAS
oncogenic RAS
Description: Ras is a family of related proteins which is expressed in all animal cell lineages and organs. All Ras protein family members belong to a class of protein called small GTPase, and are involved in transmitting signals within cells

ONECUT1
ONECUT1
Description: Hepatocyte nuclear factor 6

Curator: Bruce May
P16INK4A
P16INK4A
Description: p16Ink4a is a protein involved in regulation of the cell cycle. Currently, p16Ink4a is considered a tumor suppressor protein

P23
P23
Description: Prostaglandin E synthase 3

PAI1
PAI1
Description: Plasminogen activator inhibitor 1

Curator: Steve Jupe
PAK1
PAK1
Description: Serine/threonine-protein kinase PAK 1

Curator: Steve Jupe
PAX4
PAX4
Description: Paired box protein Pax-4

Curator: Bruce May
PAX6
PAX6
Description: Paired box protein Pax-6

Curator: Bruce May
PDX1
PDX1
Description: Pancreas/duodenum homeobox protein 1

Curator: Bruce May
peptides
peptides
Description: Peptides are biologically occurring short chains of amino acid monomers linked by peptide (amide) bonds

Curator: Steve Jupe
PERK
PERK
Description: Eukaryotic translation initiation factor 2-alpha kinase 3, dimer

Curator: Bruce May
PI3K
PI3K
Description: Phosphoinositide 3-kinase

Curator: Steve Jupe
PKC
PKC
Description: Protein kinase C

Curator: Steve Jupe
plasmin
plasmin
Description: Plasmin

Curator: Steve Jupe
plasminogen
plasminogen
Description: Plasminogen

Curator: Steve Jupe
PLCbeta1
PLCbeta1
Description: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

Curator: Steve Jupe
PLCepsilon1
PLCepsilon1
Description: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

Curator: Steve Jupe
PLCgamma1
PLCgamma1
Description: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Curator: Steve Jupe
podocin
podocin
Description: Podocin is a protein component of the filtration slits of podocytes. Glomerular capillary endothelial cells, the glomerular basement membrane and the filtration slits function as the filtration barrier of the kidney glomerulus

Curator: Steve Jupe
POFUT1
POFUT1
Description: GDP-fucose protein O-fucosyltransferase 1

POGLUT1
POGLUT1
Description: Protein O-glucosyltransferase 1

POLRMT
POLRMT
Description: DNA-directed RNA polymerase, mitochondrial

Curator: Bruce May
PPAR-gamma
PPAR-gamma
Description: Peroxisome proliferator-activated receptor gamma

Curator: Bruce May
PRC2
PRC2
Description: Histone-lysine N-methyltransferase EZH2

Curator: Bruce May
PRMT5
PRMT5
Description: Protein arginine N-methyltransferase 5

pro-CASPASE 8
pro-CASPASE 8
Description: Pro Caspase-8

procollagen
procollagen
Description: Pro-collagen

Curator: Steve Jupe
prolactin
prolactin
Description: Prolactin

Curator: Steve Jupe
protein generic
protein generic
Description: Representation of a generic protein

Curator: Bruce May
pro ISG15
pro ISG15
Description: pro-ubiquitin-like protein ISG15

Curator: Steve Jupe
PSD95
PSD95
Description: Postsynaptic density protein 95 also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (discs large homolog 4) gene

Curator: Bruce May
PTCH
PTCH
Description: Protein patched homolog 1

PTPN6
PTPN6
Description: Tyrosine-protein phosphatase non-receptor type 6

Curator: Steve Jupe
PTPN11
PTPN11
Description: Tyrosine-protein phosphatase non-receptor type 11

Curator: Steve Jupe
PTPRD
PTPRD
Description: Receptor-type tyrosine-protein phosphatase delta

Curator: Steve Jupe
PTPRS
PTPRS
Description: Receptor-type tyrosine-protein phosphatase S

Curator: Steve Jupe
R-RAS
R-RAS
Description: Ras-related protein R-Ras

Curator: Steve Jupe
RABs
RABs
Description: Ras-related protein Rab-11A

Curator: Steve Jupe
RAC1
RAC1
Description: Ras-related C3 botulinum toxin substrate 1

Curator: Steve Jupe
RAP1
RAP1
Description: Ras-related protein Rap-1

Curator: Steve Jupe
RAR
RAR
Description: Retinoic acid receptor alpha

Curator: Bruce May
RAS
RAS
Description: Cellular tumor antigen p53

RET
RET
Description: Proto-oncogene tyrosine-protein kinase receptor Ret

Curator: Steve Jupe
RHO
RHO
Description: Rhodopsinw

RHOA
RHOA
Description: Transforming protein RhoA

Curator: Steve Jupe
RICK
RICK
Description: Receptor-interacting serine/threonine-protein kinase 2

Curator: Steve Jupe
RNA POL I
RNA POL I
Description: RNA polymerase I is protein-protein complex

Curator: Bruce May
RNA POL II
RNA POL II
Description: RNA polymerase II is protein-protein complex

Curator: Bruce May
RNA POL III
RNA POL III
Description: RNA polymerase III is protein-protein complex

Curator: Bruce May
RND1
RND1
Description: Rho-related GTP-binding protein Rho6

Curator: Steve Jupe
ROBO
ROBO
Description: Roundabout homolog 1

Curator: Steve Jupe
ROCK
ROCK
Description: Rho-associated protein kinase 1

Curator: Steve Jupe
RTK
RTK
Description: Epithelial discoidin domain-containing receptor 1

RXR-alpha
RXR-alpha
Description: Retinoic acid receptor RXR-alpha

Curator: Bruce May
RXR
RXR
Description: Retinoic acid receptor RXR

Curator: Bruce May
SALM1
SALM1
Description: Leucine-rich repeat and fibronectin type-III domain-containing protein 2

Curator: Steve Jupe
SALM3
SALM3
Description: Leucine-rich repeat and fibronectin type-III domain-containing protein 4

Curator: Steve Jupe
SCAP
SCAP
Description: Sterol regulatory element-binding protein cleavage-activating protein

SEMA3A
SEMA3A
Description: Semaphorin-3A

Curator: Steve Jupe
SEMA4D PLXNB1
SEMA4D PLXNB1
Description: Semaphorin-4D and Plexin-B1

Curator: Steve Jupe
SETD8
SETD8
Description: N-lysine methyltransferase KMT5A

SFTPA1
SFTPA1
Description: Pulmonary surfactant-associated protein A1

Curator: Bruce May
SHANK
SHANK
Description: SH3 and multiple ankyrin repeat domains protein 1

Curator: Steve Jupe
SHC1
SHC1
Description: SHC-transforming protein 1

Curator: Steve Jupe
sialyntransferase
sialyntransferase
Description: Sialyltransferases are enzymes that transfer sialic acid to nascent oligosaccharide

SIRPA
SIRPA
Description: Tyrosine-protein phosphatase non-receptor type substrate 1

Curator: Steve Jupe
SLIT2
SLIT2
Description: Slit homolog 2 protein

Curator: Steve Jupe
SLITRK
SLITRK
Description: SLIT and NTRK-like protein 1

Curator: Steve Jupe
SMAD
SMAD
Description: Generic Mothers against decapentaplegic homolog

SMAD2 3
SMAD2 3
Description: Mothers against decapentaplegic homolog 2 and 3

Curator: Bruce May
SMAD4
SMAD4
Description: Mothers against decapentaplegic homolog 4

Curator: Bruce May
SOCS3
SOCS3
Description: Suppressor of cytokine signaling 3

Curator: Steve Jupe
SOD1
SOD1
Description: Superoxide dismutase [Cu-Zn]

SOD2
SOD2
Description: Superoxide dismutase [Mn], mitochondrial

SOD3
SOD3
Description: Extracellular superoxide dismutase [Cu-Zn]

SOS1
SOS1
Description: Son of sevenless homolog 1

Curator: Steve Jupe
SOX2
SOX2
Description: Transcription factor SOX-2

Curator: Bruce May
SPAG9
SPAG9
Description: C-Jun-amino-terminal kinase-interacting protein 4

Curator: Bruce May
SRC1
SRC1
Description: Proto-oncogene tyrosine-protein kinase Src

Curator: Steve Jupe
SREBP
SREBP
Description: Sterol regulatory element-binding protein 1

SRGAP
SRGAP
Description: SLIT-ROBO Rho GTPase-activating protein 2

Curator: Steve Jupe
STAT1
STAT1
Description: Signal transducer and activator of transcription 1

Curator: Steve Jupe
STAT2
STAT2
Description: Signal transducer and activator of transcription 2

Curator: Steve Jupe
STAT3
STAT3
Description: Signal transducer and activator of transcription 3

Curator: Steve Jupe
STAT4
STAT4
Description: Signal transducer and activator of transcription 4

Curator: Steve Jupe
STAT5
STAT5
Description: Signal transducer and activator of transcription 5

Curator: Steve Jupe
STAT6
STAT6
Description: Signal transducer and activator of transcription 6

Curator: Steve Jupe
STAT generic
STAT generic
Description: Signal transducer and activator of transcription family

Curator: Steve Jupe
STING
STING
Description: Stimulator of interferon genes protein

Curator: Steve Jupe
STXBP1
STXBP1
Description: {DESCRIPTION}

Curator: Steve Jupe
SYK
SYK
Description: Tyrosine-protein kinase SYK

Curator: Steve Jupe
TAK1
TAK1
Description: Mitogen-activated protein kinase kinase kinase 7

Curator: Steve Jupe
TFAM
TFAM
Description: Transcription factor A, mitochondrial

Curator: Bruce May
TFB2M
TFB2M
Description: Dimethyladenosine transferase 2, mitochondrial

Curator: Bruce May
THROMBIN
THROMBIN
Description: Thrombin (factor 2a)

Curator: Steve Jupe
TIRAP
TIRAP
Description: Toll/interleukin-1 receptor domain-containing adapter protein

Curator: Steve Jupe
tPA
tPA
Description: Tissue-type plasminogen activator

Curator: Steve Jupe
TRAF2
TRAF2
Description: TNF receptor-associated factor 2

Curator: Steve Jupe
TRAF3
TRAF3
Description: TNF receptor-associated factor 3

Curator: Steve Jupe
TRAF6
TRAF6
Description: TNF receptor-associated factor 6

Curator: Steve Jupe
TRAM
TRAM
Description: Translocating chain-associated membrane protein 1

Curator: Steve Jupe
TRIF
TRIF
Description: TIR domain-containing adapter molecule 2

Curator: Steve Jupe
tropocollagen
tropocollagen
Description: Tropocollagen

Curator: Steve Jupe
TXA2
TXA2
Description: Thromboxane A2 receptor

Curator: Steve Jupe
TYK2
TYK2
Description: Non-receptor tyrosine-protein kinase TYK2

Curator: Steve Jupe
UBA7
UBA7
Description: Ubiquitin-like modifier-activating enzyme 7

Curator: Steve Jupe
UBCH8
UBCH8
Description: Ubiquitin/ISG15-conjugating enzyme E2 L6

Curator: Steve Jupe
ubiquitin
ubiquitin
Description: Ubiquitin

Curator: Steve Jupe
USP18
USP18
Description: Ubl carboxyl-terminal hydrolase 18

Curator: Steve Jupe
viral protein
viral protein
Description: Viral protein

Curator: Steve Jupe
viral protein dissolved
viral protein dissolved
Description: Viral protein, dissolved

Curator: Steve Jupe
vWF
vWF
Description: von Willebrand factor

Curator: Steve Jupe
Wnt
Wnt
Description: Proto-oncogene Wnt-1

YAP
YAP
Description: Transcriptional coactivator YAP1

ZAP70
ZAP70
Description: Tyrosine-protein kinase ZAP-70

Curator: Steve Jupe
ZNF385A
ZNF385A
Description: Cellular tumor antigen p53


Please refer to the guidelines for more information about the process of creating and sharing icons.
We would like to develop the Icon Library further as a community resource. If you use library elements, and design similar elements which are still missing, we would be very happy to incorporate them into the library, naming you as the author. Contact us at help@reactome.org.
The software and information contents are distributed under the terms of the Creative Commons Attribution 4.0 International License, which grants parties the non-exclusive right to use, distribute and create derivative works based on Reactome, provided that the software and information is correctly attributed to CSHL, OICR and EBI. Find more information about the license here.