There will be a maintenance on OICR IT systems starting Friday Dec 15 at 6PM EST until midnight Sunday Dec 17; Reactome will be affected by this downtime

Service under maintenance from Friday Dec 15 at 6PM EST until midnight Sunday Dec 17

Graph Database :: Data Schema

Graph Database :: Data Schema

×
Entries: EntityFunctionalStatus
Identifier Name
4839737 decreased_transcript_level and loss_of_function of truncation and missense AXIN mutants [cytosol]
5251549 decreased_transcript_level of defective AMER1 gene [nucleoplasm]
5251552 decreased_transcript_level of defective AXIN1 gene [nucleoplasm]
5683224 gain_of_function of ABCC8 mutants (PNDM, TNDM2) [plasma membrane]
2362350 gain_of_function of AKT1 E17K [cytosol]
3080617 gain_of_function of AKT1 E17K mutant:PIP2 [plasma membrane]
5655258 gain_of_function of Activated FGFR1 mutants [plasma membrane]
5654440 gain_of_function of Activated FGFR1 mutants and fusion:p-PLCG1 [cytosol]
5654444 gain_of_function of Activated FGFR1 mutants and fusions:PLCG1 [cytosol]
5655333 gain_of_function of Activated FGFR1 mutants:FRS2 [plasma membrane]
5655256 gain_of_function of Activated FGFR1 mutants:p-FRS2 [plasma membrane]
5655220 gain_of_function of Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]
5655349 gain_of_function of Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane]
5655334 gain_of_function of Activated FGFR2 mutants [plasma membrane]
5655264 gain_of_function of Activated FGFR2 mutants:FRS2 [plasma membrane]
5655246 gain_of_function of Activated FGFR2 mutants:PLCG1 [plasma membrane]
5654744 gain_of_function of Activated FGFR2 mutants:p-4Y-PLCG1 [plasma membrane]
5655327 gain_of_function of Activated FGFR2 mutants:p-FRS2 [plasma membrane]
5655283 gain_of_function of Activated FGFR2 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]
5655288 gain_of_function of Activated FGFR2 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane]
5655276 gain_of_function of Activated FGFR3 mutants [plasma membrane]
5655260 gain_of_function of Activated FGFR3 mutants: PLCG1 [plasma membrane]
5655239 gain_of_function of Activated FGFR3 mutants:FRS2 [plasma membrane]
5655338 gain_of_function of Activated FGFR3 mutants:p-4Y-PLCG1 [plasma membrane]
5655314 gain_of_function of Activated FGFR3 mutants:p-FRS2 [plasma membrane]
5655286 gain_of_function of Activated FGFR3 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]
5655306 gain_of_function of Activated FGFR3 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane]
5655335 gain_of_function of Activated FGFR4 mutants [plasma membrane]
5655322 gain_of_function of Activated FGFR4 mutants:FRS2 [plasma membrane]
5655281 gain_of_function of Activated FGFR4 mutants:PLCG1 [plasma membrane]
5655310 gain_of_function of Activated FGFR4 mutants:p-4Y-PLCG1 [plasma membrane]
5655325 gain_of_function of Activated FGFR4 mutants:p-FRS2 [plasma membrane]
5655300 gain_of_function of Activated FGFR4 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]
5655309 gain_of_function of Activated FGFR4 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane]
5637732 gain_of_function of Active dimers of ligand-responsive EGFR mutants [plasma membrane]
5654534 gain_of_function of BCR-p-FGFR1 fusion mutant dimer [cytosol]
6802860 gain_of_function of BRAF/RAF fusion dimers [cytosol]
2775817 gain_of_function of DLL/JAG:NOTCH1 PEST Domain Mutants [plasma membrane]
5637729 gain_of_function of EGF:Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane]
5638088 gain_of_function of EGFRvIII mutant dimer [plasma membrane]
5654445 gain_of_function of FGFR1 P252X mutant dimers bound to FGFs [plasma membrane]
5654502 gain_of_function of FGFR1 P252X mutants [plasma membrane]
5654448 gain_of_function of FGFR1 mutant dimers with enhanced kinase activity [plasma membrane]
5654486 gain_of_function of FGFR1 mutants with enhanced kinase activity [plasma membrane]
5655293 gain_of_function of FGFR1 mutants:p-FRS2:GRB2:SOS1 [plasma membrane]
5654512 gain_of_function of FGFR1OP-p-FGFR1 fusion mutant dimer [cytosol]
5654529 gain_of_function of FGFR1b [plasma membrane]
5654531 gain_of_function of FGFR1b homodimer [plasma membrane]
5654542 gain_of_function of FGFR1c [plasma membrane]
5654546 gain_of_function of FGFR1c homodimer [plasma membrane]
8853299 gain_of_function of FGFR2 IIIa TM [extracellular region]
8853297 gain_of_function of FGFR2 fusion dimers [plasma membrane]
8853294 gain_of_function of FGFR2 fusions [plasma membrane]
5654449 gain_of_function of FGFR2 ligand-independent mutant dimers [plasma membrane]
5654488 gain_of_function of FGFR2 ligand-independent mutants [plasma membrane]