Reactome | ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose

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((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose Show undefined attributes

catalystActivity	[CatalystActivity:71551] amylo-alpha-1,6-glucosidase activity of AGL [cytosol]
catalystActivityReference	[CatalystActivityReference:9644006] amylo-alpha-1,6-glucosidase activity of AGL [cytosol] Glycogen debranching enzyme: purification, antibody characterization, and immunoblot analyses of type III glycogen storage disease.
category	transition
compartment	[Compartment:70101] cytosol
dbId	71593
displayName	((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose
eventOf	[Pathway:R-HSA-70221] Glycogen breakdown (glycogenolysis) - Homo sapiens
followingEvent	[Reaction:R-HSA-453339] poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] - Homo sapiens [Reaction:R-HSA-453358] poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] - Homo sapiens
input	[DefinedSet:R-HSA-453350] ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)GYG dimer [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:71546] Glycogen debranching enzyme: purification, antibody characterization, and immunoblot analyses of type III glycogen storage disease. [LiteratureReference:199678] Mutations in the liver glycogen synthase gene in children with hypoglycemia due to glycogen storage disease type 0
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose
orthologousEvent	[Reaction:R-SCE-71593] ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose - Saccharomyces cerevisiae [Reaction:R-DDI-71593] ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose - Dictyostelium discoideum [Reaction:R-CEL-71593] ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose - Caenorhabditis elegans [Reaction:R-DME-71593] ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose - Drosophila melanogaster [Reaction:R-GGA-71593] ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose - Gallus gallus [Reaction:R-XTR-71593] ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose - Xenopus tropicalis [Reaction:R-SSC-71593] ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose - Sus scrofa [Reaction:R-BTA-71593] ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose - Bos taurus [Reaction:R-CFA-71593] ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose - Canis familiaris [Reaction:R-RNO-71593] ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose - Rattus norvegicus [Reaction:R-MMU-71593] ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose - Mus musculus
output	[SimpleEntity:R-ALL-70113] Glc [cytosol] [DefinedSet:R-HSA-453224] poly((1,4)-alpha-glucosyl)GYG dimer [cytosol]
precedingEvent	[Reaction:R-HSA-71552] limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:453329] D'Eustachio, P, 2010-01-21
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-71593
summation	[Summation:179340] At the beginning of this reaction, 1 molecule of '{(1,6)-alp...

Referrals

(hasEvent)	[Pathway:R-HSA-70221] Glycogen breakdown (glycogenolysis)
(precedingEvent)	[Reaction:R-HSA-453339] poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] [Reaction:R-HSA-453358] poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]

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