Reactome | (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)

Schema > Reaction > Entries

(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) Show undefined attributes

authored	[InstanceEdit:504064] D'Eustachio, P, 2010-02-05
catalystActivity	[CatalystActivity:482613] nucleoside diphosphate kinase activity of NME1,2 hexamers [cytosol]
catalystActivityReference	[CatalystActivityReference:9643341] nucleoside diphosphate kinase activity of NME1,2 hexamers [cytosol] Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:482616] D'Eustachio, P, 2010-01-28
dbId	482621
displayName	(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)
edited	[InstanceEdit:504064] D'Eustachio, P, 2010-02-05
eventOf	[Pathway:R-HSA-499943] Interconversion of nucleotide di- and triphosphates - Homo sapiens
input	[DefinedSet:R-ALL-482625] (d)NTP [cytosol] [SimpleEntity:R-ALL-29370] ADP [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:110581] Enzymatic phosphorylation of nucleoside diphosphates [LiteratureReference:482617] Nucleotide binding to nucleoside diphosphate kinases: X-ray structure of human NDPK-A in complex with ADP and comparison to protein kinases [LiteratureReference:110625] Structural and catalytic properties and homology modelling of the human nucleoside diphosphate kinase C, product of the DRnm23 gene [LiteratureReference:110596] Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme [Book:110590] The Enzymes, 3rd ed Boyer, PD Nucleoside diphosphokinases 0121227022 [LiteratureReference:110592] Substrate specificity of human nucleoside-diphosphate kinase revealed by transient kinetic analysis
modified	[InstanceEdit:10931649] Wright, Adam, 2024-03-08
name	(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)
orthologousEvent	[Reaction:R-PFA-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Plasmodium falciparum [Reaction:R-SCE-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Saccharomyces cerevisiae [Reaction:R-SPO-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Schizosaccharomyces pombe [Reaction:R-DDI-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Dictyostelium discoideum [Reaction:R-CEL-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Caenorhabditis elegans [Reaction:R-DME-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Drosophila melanogaster [Reaction:R-GGA-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Gallus gallus [Reaction:R-XTR-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Xenopus tropicalis [Reaction:R-DRE-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Danio rerio [Reaction:R-SSC-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Sus scrofa [Reaction:R-BTA-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Bos taurus [Reaction:R-CFA-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Canis familiaris [Reaction:R-RNO-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Rattus norvegicus [Reaction:R-MMU-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Mus musculus
output	[DefinedSet:R-ALL-482627] (d)NDP [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol]
precedingEvent	[Reaction:R-HSA-73647] UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] - Homo sapiens
releaseDate	2010-03-16
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:165071] Graves, L, Rush, MG, 0000-00-00 00:00:00
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-482621
summation	[Summation:482624] Cytosolic nucleoside diphosphate kinases catalyze the revers...

Referrals

(hasEvent)	[Pathway:R-HSA-499943] Interconversion of nucleotide di- and triphosphates
(reverseReaction)	[Reaction:R-HSA-482619] (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3)

Cite Us!