Reactome | AP-1 stimulates transcription of IGFBP7

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AP-1 stimulates transcription of IGFBP7 Show undefined attributes

authored	[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:984] extracellular region
created	[InstanceEdit:3797207] Orlic-Milacic, M, 2013-07-05
dbId	3797202
displayName	AP-1 stimulates transcription of IGFBP7
edited	[InstanceEdit:3901124] D'Eustachio, P, 2013-07-15 [InstanceEdit:4542306] Matthews, L, 2013-07-15
eventOf	[Pathway:R-HSA-2559582] Senescence-Associated Secretory Phenotype (SASP) - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-3797198] IGFBP7 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3797206] Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	AP-1 stimulates transcription of IGFBP7
output	[EntityWithAccessionedSequence:R-HSA-3214900] IGFBP7 [extracellular region]
precedingEvent	[Reaction:R-HSA-3797196] AP-1 transcription factor binds IGFBP7 promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-3797200] Positive gene expression regulation by 'p-2S-JUN:p-2S,2T-FOS:IGFBP7 Gene [nucleoplasm]'
regulationReference	[RegulationReference:9641439] Positive gene expression regulation by 'p-2S-JUN:p-2S,2T-FOS:IGFBP7 Gene [nucleoplasm]' Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7
releaseDate	2013-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-3797202
summation	[Summation:3797201] FOS:JUN (AP-1) transcription factor stimulates the transcrip...

Referrals

(hasEvent)

[Pathway:R-HSA-2559582] Senescence-Associated Secretory Phenotype (SASP)

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