Reactome | A tetrasaccharide linker sequence is required for GAG synthesis

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A tetrasaccharide linker sequence is required for GAG synthesis Show undefined attributes

authored	[InstanceEdit:1971508] Jassal, B, 2011-11-04
created	[InstanceEdit:1971508] Jassal, B, 2011-11-04
crossReference	[DatabaseIdentifier:12325598] BioModels Database:BIOMD0000000930
dbId	1971475
displayName	A tetrasaccharide linker sequence is required for GAG synthesis
edited	[InstanceEdit:1971508] Jassal, B, 2011-11-04
eventOf	[Pathway:R-HSA-1793185] Chondroitin sulfate/dermatan sulfate metabolism - Homo sapiens [Pathway:R-HSA-1638091] Heparan sulfate/heparin (HS-GAG) metabolism - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:3777] glycosaminoglycan metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-1878002] XYLTs transfer Xyl to core protein - Homo sapiens [Reaction:R-HSA-1889981] B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker - Homo sapiens [Reaction:R-HSA-1889978] B3GALT6 transfers Gal to the tetrasaccharide linker - Homo sapiens [Reaction:R-HSA-1889955] B3GAT dimers transfer GlcA to tetrasaccharide linker - Homo sapiens [Reaction:R-HSA-9638064] B3GAT3 dimer transfers GlcA to tetrasaccharide linker - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1971426] Biosynthesis of chondroitin sulfate: from the early, precursor discoveries to nowadays, genetics approaches [LiteratureReference:1971518] Glycosaminoglycans. A biochemical and clinical review
modified	[InstanceEdit:12325341] Wright, Adam, 2024-02-14
name	A tetrasaccharide linker sequence is required for GAG synthesis
orthologousEvent	[Pathway:R-CEL-1971475] A tetrasaccharide linker sequence is required for GAG synthesis - Caenorhabditis elegans [Pathway:R-DME-1971475] A tetrasaccharide linker sequence is required for GAG synthesis - Drosophila melanogaster [Pathway:R-GGA-1971475] A tetrasaccharide linker sequence is required for GAG synthesis - Gallus gallus [Pathway:R-XTR-1971475] A tetrasaccharide linker sequence is required for GAG synthesis - Xenopus tropicalis [Pathway:R-DRE-1971475] A tetrasaccharide linker sequence is required for GAG synthesis - Danio rerio [Pathway:R-SSC-1971475] A tetrasaccharide linker sequence is required for GAG synthesis - Sus scrofa [Pathway:R-BTA-1971475] A tetrasaccharide linker sequence is required for GAG synthesis - Bos taurus [Pathway:R-CFA-1971475] A tetrasaccharide linker sequence is required for GAG synthesis - Canis familiaris [Pathway:R-RNO-1971475] A tetrasaccharide linker sequence is required for GAG synthesis - Rattus norvegicus [Pathway:R-MMU-1971475] A tetrasaccharide linker sequence is required for GAG synthesis - Mus musculus
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2172129] D'Eustachio, P, 2012-03-28
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-1971475
summation	[Summation:1971447] The biosynthesis of dermatan sulfate/chondroitin sulfate and...

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