Reactome | 2-LTR circle formation

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2-LTR circle formation Show undefined attributes

authored	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:164848] Gopinathrao, G, 2005-06-29 16:40:43
dbId	164843
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	2-LTR circle formation
edited	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
eventOf	[Pathway:R-HSA-162592] Integration of provirus - Homo sapiens
figure	[Figure:175998] /figures/2ltrx.jpg
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-175174] Association of Ku heterodimer with viral DNA ends - Homo sapiens [Reaction:R-HSA-175177] Association of XRCC4:DNA ligase IV complex with viral DNA ends - Homo sapiens [Reaction:R-HSA-175258] 2-LTR formation due to circularization of viral DNA - Homo sapiens
isInDisease	true
isInferred	false
literatureReference	[Book:175927] 9780879695712 Integration Retroviruses Coffin, JM [LiteratureReference:177403] Retroviral DNA integration--mechanism and consequences [LiteratureReference:177396] Genome-wide analysis of retroviral DNA integration
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	2-LTR circle formation
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2006-11-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:188934] Bushman, FD, 2006-10-30 22:19:13
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-164843
summation	[Summation:180109] The formation of 2-LTR circles requires the action of the ce...

Referrals

(hasEvent)

[Pathway:R-HSA-162592] Integration of provirus