Reactome | Acetylation

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Acetylation Show undefined attributes

authored	[InstanceEdit:156610] Jassal, B, 2004-11-30 16:21:24
created	[InstanceEdit:156583] Jassal, B, 2004-11-29 11:42:34
dbId	156582
displayName	Acetylation
edited	[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
eventOf	[Pathway:R-HSA-156580] Phase II - Conjugation of compounds - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:8764] xenobiotic metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-174959] The acetyl group from acetyl-CoA is transferred to the NAT1 - Homo sapiens [Reaction:R-HSA-158832] The acetyl group from acetyl-CoA is transferred to the NAT2 - Homo sapiens [Reaction:R-HSA-174963] NAT1 acetylation - Homo sapiens [Reaction:R-HSA-174967] NAT2 acetylation - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[Book:76380] 9780071470513 Parkinson, A Casarett and Doull's Toxicology 5th Edn [LiteratureReference:158679] Arylamine N-acetyltransferases and drug response [LiteratureReference:158684] Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression [LiteratureReference:158835] Site-directed mutagenesis of recombinant human arylamine N-acetyltransferase expressed in Escherichia coli. Evidence for direct involvement of Cys68 in the catalytic mechanism of polymorphic human NAT2.
modified	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
name	Acetylation
orthologousEvent	[Pathway:R-GGA-156582] Acetylation - Gallus gallus [Pathway:R-DRE-156582] Acetylation - Danio rerio [Pathway:R-SSC-156582] Acetylation - Sus scrofa [Pathway:R-BTA-156582] Acetylation - Bos taurus [Pathway:R-RNO-156582] Acetylation - Rattus norvegicus [Pathway:R-MMU-156582] Acetylation - Mus musculus
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-156582
summation	[Summation:156612] N-acetyltransferases (NATs; EC 2.3.1.5) utilize acetyl Co-A ...

Referrals

(hasEvent)

[Pathway:R-HSA-156580] Phase II - Conjugation of compounds