Reactome | (d)GDP + ADP <=> (d)GMP + ATP (GUK1)

Schema > Reaction > Entries

(d)GDP + ADP <=> (d)GMP + ATP (GUK1) Show undefined attributes

catalystActivity	[CatalystActivity:74189] guanylate kinase activity of GUK1 [cytosol]
catalystActivityReference	[CatalystActivityReference:9643996] guanylate kinase activity of GUK1 [cytosol] Cloning, characterization, and modeling of mouse and human guanylate kinases
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:110076] D'Eustachio, P, 2004-01-28 17:55:00
crossReference	[DatabaseIdentifier:11880800] Rhea:20782 [DatabaseIdentifier:11881156] Rhea:12699
dbId	110133
displayName	(d)GDP + ADP <=> (d)GMP + ATP (GUK1)
eventOf	[Pathway:R-HSA-499943] Interconversion of nucleotide di- and triphosphates - Homo sapiens
input	[DefinedSet:R-ALL-500077] (d)GDP [cytosol] [SimpleEntity:R-ALL-29370] ADP [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:110117] Guanylate kinases from human erythrocytes, hog brain, and rat liver [LiteratureReference:500070] Cloning, characterization, and modeling of mouse and human guanylate kinases [LiteratureReference:110100] Studies on the properties and tissue distribution of the isozymes of guanylate kinase in man [LiteratureReference:110121] Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	(d)GDP + ADP <=> (d)GMP + ATP (GUK1)
orthologousEvent	[Reaction:R-PFA-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Plasmodium falciparum [Reaction:R-SCE-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Saccharomyces cerevisiae [Reaction:R-SPO-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Schizosaccharomyces pombe [Reaction:R-DDI-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Dictyostelium discoideum [Reaction:R-CEL-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Caenorhabditis elegans [Reaction:R-DME-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Drosophila melanogaster [Reaction:R-GGA-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Gallus gallus [Reaction:R-XTR-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Xenopus tropicalis [Reaction:R-DRE-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Danio rerio [Reaction:R-SSC-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Sus scrofa [Reaction:R-BTA-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Bos taurus [Reaction:R-CFA-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Canis familiaris [Reaction:R-RNO-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Rattus norvegicus [Reaction:R-MMU-110133] (d)GDP + ADP <=> (d)GMP + ATP (GUK1) - Mus musculus
output	[DefinedSet:R-ALL-500071] (d)GMP [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:504064] D'Eustachio, P, 2010-02-05
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-110133
summation	[Summation:500078] Cytosolic guanylate kinase 1 (GUK1) catalyzes the reversible...

Referrals

(hasEvent)	[Pathway:R-HSA-499943] Interconversion of nucleotide di- and triphosphates
(reverseReaction)	[Reaction:R-HSA-73788] (d)GMP + ATP <=> (d)GDP + ADP (GUK1)

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