Reactome | Phosphorylated AKT1S1:mTORC1 binds YWHAB

Schema > Reaction > Entries

category	binding
compartment	[Compartment:17938] lysosomal membrane [Compartment:70101] cytosol
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9940438
displayName	Phosphorylated AKT1S1:mTORC1 binds YWHAB
eventOf	[Pathway:R-MMU-165159] MTOR signalling - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5672824] Phosphorylated AKT1S1:mTORC1 binds YWHAB - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-1445100] 14-3-3 beta/alpha [cytosol] [Complex:R-MMU-377420] mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane]
isInDisease	false
isInferred	true
name	Phosphorylated AKT1S1:mTORC1 binds YWHAB
output	[Complex:R-MMU-5672861] mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5672824
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-165159] MTOR signalling
(inferredTo)	[Reaction:R-HSA-5672824] Phosphorylated AKT1S1:mTORC1 binds YWHAB