Reactome | C7 binds C5b:C6

Schema > Reaction > Entries

C7 binds C5b:C6 Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9877742
displayName	C7 binds C5b:C6
eventOf	[Pathway:R-MMU-166665] Terminal pathway of complement - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-2530453] Vitronectin (VTN) binds to C5b:C6:C7 - Mus musculus [Reaction:R-MMU-173720] C5b:C6:C7 translocates to the plasma membrane - Mus musculus
inferredFrom	[Reaction:R-HSA-173709] C7 binds C5b:C6 - Homo sapiens
input	[Complex:R-MMU-173711] C5b:C6 [extracellular region] [EntityWithAccessionedSequence:R-MMU-173707] C7 [extracellular region]
isInDisease	false
isInferred	true
name	C7 binds C5b:C6
output	[Complex:R-MMU-173708] C5b:C6:C7 [extracellular region]
precedingEvent	[Reaction:R-MMU-173705] C5b binds C6 - Mus musculus
regulatedBy	[NegativeRegulation:9877743] Negative regulation by 'CLU:C5b:C6:C7, C8, C9 [extracellular region]'
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-173709
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-166665] Terminal pathway of complement
(precedingEvent)	[Reaction:R-MMU-2530453] Vitronectin (VTN) binds to C5b:C6:C7 [Reaction:R-MMU-173720] C5b:C6:C7 translocates to the plasma membrane
(inferredTo)	[Reaction:R-HSA-173709] C7 binds C5b:C6