Reactome | Measles virus

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Measles virus Show undefined attributes

abbreviation	MVI
created	[InstanceEdit:9013949] Shamovsky, Veronica, 2017-07-26
crossReference	[DatabaseIdentifier:9013947] NCBI Taxonomy:11234
dbId	9013948
displayName	Measles virus
modified	[InstanceEdit:9034578] D'Eustachio, Peter, 2018-01-08
name	Measles virus rubeola virus rougeole virus
schemaClass	Species
superTaxon	[Taxon:9034572] Morbillivirus
taxId	11234

Referrals

(relatedSpecies)

[Pathway:R-HSA-168928] DDX58/IFIH1-mediated induction of interferon-alpha/beta
[Pathway:R-HSA-933541] TRAF6 mediated IRF7 activation
[Reaction:R-HSA-9705323] Phosphorylation of TBK1/IKBKE
[Reaction:R-HSA-9705145] TBK1, IKBKE form homodimers
[Reaction:R-HSA-933525] Phosphorylation and release of IRF7
[Reaction:R-HSA-933538] Recruitment of IRF7 to TRAF6
[Reaction:R-HSA-933527] Recruitment of TBK1/IKK epsilon complex to TANK:TRAF6
[Reaction:R-HSA-933537] Recruitment of TANK to TRAF6
[Complex:R-HSA-933479] dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK:TBK1/IKBKE [mitochondrial outer membrane]
[Complex:R-HSA-933470] dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK:TBK1/IKBKE:IRF7 [mitochondrial outer membrane]
[Complex:R-HSA-9705317] dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK:2xpS172-TBK1/IKBKE [mitochondrial outer membrane]
[Pathway:R-HSA-933543] NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
[Reaction:R-HSA-933539] Recruitment of IKK complex
[Complex:R-HSA-933478] dsRNA:RIG-I/MDA5:TRAF2/TRAF6:IPS-1:RIP-1/FADD:Casp-8/10 prodomain:IKK complex [mitochondrial outer membrane]
[Complex:R-HSA-933473] viral dsRNA:RIG-I/MDA5:TRAF2/TRAF6:IPS-1:RIP-1/FADD:Casp-8/10 prodomain [mitochondrial outer membrane]
[Reaction:R-HSA-933532] Processing of caspases
[Complex:R-HSA-913727] viral dsRNA:IFIH1 [cytosol]
[DefinedSet:R-HSA-918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol]
[Complex:R-HSA-937325] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP:NLRC5 [cytosol]
[Complex:R-HSA-918201] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS [mitochondrial outer membrane]
[Complex:R-HSA-918200] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3 [mitochondrial outer membrane]
[Complex:R-HSA-918196] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:TBK1/IKBKE [mitochondrial outer membrane]
[Reaction:R-HSA-913725] viral dsRNA binds IFIH1:TKFC
[Reaction:R-HSA-168909] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58 bind MAVS
[Reaction:R-HSA-918227] Recruitment of TRAF3 to MAVS
[Reaction:R-HSA-918225] TBK1/IKK epsilon complex interacts with MAVS bound TRAF3
[Complex:R-HSA-9705133] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2xIKK related kinases TBK1/IKK epsilon [mitochondrial outer membrane]
[Complex:R-HSA-933467] dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane]
[Complex:R-HSA-933472] dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK [mitochondrial outer membrane]
[Complex:R-HSA-9705147] dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK:2xTBK1/IKBKE [mitochondrial outer membrane]
[Complex:R-HSA-9710999] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2x(TBK1/IKBKE) [mitochondrial outer membrane]
[Reaction:R-HSA-9705137] TBK1 or IKBKE forms homodimers
[Reaction:R-HSA-9705320] TBK1, IKBKE are autophosphorylated at Ser172
[Complex:R-HSA-983462] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:PCBP2 [mitochondrial outer membrane]
[Reaction:R-HSA-990528] Interaction of PCBP2 with MAVS
[Reaction:R-HSA-937343] NLRC5 interacts with DDX58/IFIH1
[Complex:R-HSA-983461] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP:K48polyUb-MAVS [mitochondrial outer membrane]
[Complex:R-HSA-983459] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:PCBP2:ITCH [mitochondrial outer membrane]
[Reaction:R-HSA-990526] Recruitment of ITCH and K48 ubiquitination of MAVS
[Complex:R-HSA-936558] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:TRAF3 [mitochondrial outer membrane]
[Reaction:R-HSA-936381] OTUD5 deubiquitinates TRAF3
[Complex:R-HSA-936400] dsRNA:RIG-I/MDA5:IPS-1:ATG5-ATG12 [mitochondrial outer membrane]
[Reaction:R-HSA-936378] Inhibition of DDX58/IFIH1 signaling by ATG5:ATG12:MAVS
[BlackBoxEvent:R-HSA-936475] Negative regulation of DDX58/IFIH1 signaling by RNF216
[Pathway:R-HSA-936440] Negative regulators of DDX58/IFIH1 signaling
[Complex:R-HSA-918199] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2xTBK1,IKBKE:IRF3,IRF7 [mitochondrial outer membrane]
[Reaction:R-HSA-918232] Recruitment of IRF3,IRF7
[Reaction:R-HSA-918229] Phosphorylation and release of IRF3/IRF7
[Complex:R-HSA-933482] dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:MEKK1 [mitochondrial outer membrane]
[Reaction:R-HSA-918230] Recruitment of TRAF6/TRAF2 to IPS-1
[Reaction:R-HSA-933528] Interaction of MEKK1 with TRAF6
[Reaction:R-HSA-933530] Activation of IKK by MEKK1
[Complex:R-HSA-918291] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:RIPK1:FADD [mitochondrial outer membrane]
[Complex:R-HSA-933483] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:RIPK1:FADD:2xCASP8(1-479), CASP10(1-521) [mitochondrial outer membrane]
[Complex:R-HSA-8983917] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:RIPK1:FADD:CASP8(1-216), CASP10(1-219) [mitochondrial outer membrane]
[Complex:R-HSA-8983916] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:RIPK1:FADD:2xCASP8(1-216), CASP10(1-219) [mitochondrial outer membrane]
[Complex:R-HSA-933468] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:RIPK1:FADD:CASP8(1-479), CASP10(1-521) [mitochondrial outer membrane]
[Reaction:R-HSA-168934] MAVS interacts with RIPK1 and FADD
[Reaction:R-HSA-933526] Recruitment of caspase-8 and -10 to FADD complex
[Reaction:R-HSA-933523] Dimerzation of procaspase-8, procaspase-10

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