Reactome | Abbott, DW

Schema > Person > Entries

Abbott, DW Show undefined attributes

created	[InstanceEdit:5657672] Shamovsky, V, 2014-12-16
dbId	5657671
displayName	Abbott, DW
firstname	Derek W
initial	DW
publications	[LiteratureReference:741404] The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO [LiteratureReference:1247994] Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains [LiteratureReference:5657670] Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation [LiteratureReference:1248660] NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2 [LiteratureReference:9710231] Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition [LiteratureReference:9728824] Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage [LiteratureReference:1247988] ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways [LiteratureReference:9647617] Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization [LiteratureReference:5621041] Identification of RIP1 kinase as a specific cellular target of necrostatins [LiteratureReference:9710277] N-GSDMD trafficking to neutrophil organelles facilitates IL-1? release independently of plasma membrane pores and pyroptosis [LiteratureReference:5684243] I?B kinase 2 regulates TPL-2 activation of extracellular signal-regulated kinases 1 and 2 by direct phosphorylation of TPL-2 serine 400 [LiteratureReference:9647624] Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor [LiteratureReference:9710055] Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis
schemaClass	Person
surname	Abbott

Cite Us!