UniProt:A1L190 SYCE3

chain
  • chain:1-88
checksum 9A038411E08A2760
comment
  • FUNCTION Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes. Chromosome loading appears to require SYCP1. Required for fertility.SUBUNIT Homodimer. Interacts with SYCE1. Interacts with SYCE2. Interacts with proteasome subunit PSMA8; to participate in meiosis progression during spermatogenesis (By similarity). Interacts with SPO16 (By similarity).INTERACTION Colocalizes with SYCE1 in the central elements.
created [InstanceEdit:423310] Kanapin, AA
crossReference
databaseName UniProt
dbId 424514
description
  • recommendedName: Synaptonemal complex central element protein 3 alternativeName: Testis highly expressed gene 2 protein shortName: THEG-2
displayName UniProt:A1L190 SYCE3
geneName
  • SYCE3
  • C22orf41
  • THEG2
identifier A1L190
isSequenceChanged false
keyword
  • Cell cycle
  • Cell division
  • Chromosome
  • Coiled coil
  • Meiosis
  • Nucleus
  • Reference proteome
modified [InstanceEdit:12187927] Wright, Adam, 2024-03-12
name
  • SYCE3
otherIdentifier
  • 11732717_at
  • 16936643
  • 239854_PM_at
  • 239854_at
  • 3966049
  • 3966050
  • 3966051
  • 3966052
  • 3966053
  • 644186
  • A_33_P3250887
  • GE479566
  • GO:0000228
  • GO:0000801
  • GO:0005515
  • GO:0005634
  • GO:0005694
  • GO:0006310
  • GO:0006915
  • GO:0007049
  • GO:0007059
  • GO:0007130
  • GO:0007131
  • GO:0007283
  • GO:0012501
  • GO:0022414
  • GO:0030154
  • GO:0035234
  • GO:0043065
  • GO:0043226
  • GO:0048856
  • GO:0051094
  • GO:0051301
  • GO:0051321
  • GO:0140013
  • GO:2000243
  • HMNXSV003014313
  • Hs.98579.0.A1_3p_at
  • TC22000916.hg
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • SYCE3_HUMAN
sequenceLength 88
species [Species:48887] Homo sapiens
url https://purl.uniprot.org/uniprot/A1L190
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