UniProt:A1L4H1 SSC5D

chain
  • signal peptide:1-16
  • chain:17-1573
checksum 9151F14B58BD1A0D
comment
  • FUNCTION Binds to extracellular matrix proteins. Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces (By similarity).SUBUNIT Interacts with LGALS1 and laminin.INTERACTION Highly expressed in monocytes/macrophages and T-lymphocytes. Highly expressed in placenta and spleen, and also detected at lower levels in colon, and more weakly in lung, heart and kidney.SEQUENCE CAUTION Truncated N-terminus.SEQUENCE CAUTION Truncated N-terminus.
created [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12
crossReference
databaseName UniProt
dbId 356774
description
  • recommendedName: Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D alternativeName: Soluble scavenger protein with 5 SRCR domains shortName: SSc5D
displayName UniProt:A1L4H1 SSC5D
geneName
  • SSC5D
identifier A1L4H1
isSequenceChanged false
keyword
  • Alternative splicing
  • Cytoplasm
  • Developmental protein
  • Disulfide bond
  • Glycoprotein
  • Immunity
  • Innate immunity
  • Receptor
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
modified [InstanceEdit:12187927] Wright, Adam, 2024-03-12
name
  • SSC5D
otherIdentifier
  • 11725868_at
  • 16865699
  • 230228_PM_at
  • 230228_at
  • 284297
  • 3842195
  • 3842196
  • 3842197
  • 3842199
  • 3842201
  • 3842202
  • 3842204
  • 3842207
  • 3842208
  • 3842209
  • 3842210
  • 3842211
  • 3842212
  • 3842215
  • 3842216
  • 3842218
  • 3842219
  • 3842220
  • 3842221
  • 3842222
  • 3842223
  • 3842224
  • 3842225
  • 3842226
  • 3842227
  • 73819_at
  • 8031499
  • A_21_P0000127
  • A_33_P3303542
  • A_33_P3358898
  • GE852051
  • GE87604
  • GO:0001968
  • GO:0002376
  • GO:0005044
  • GO:0005515
  • GO:0005576
  • GO:0005615
  • GO:0005737
  • GO:0006897
  • GO:0006952
  • GO:0016020
  • GO:0016192
  • GO:0030312
  • GO:0031012
  • GO:0032677
  • GO:0032717
  • GO:0038024
  • GO:0042494
  • GO:0043236
  • GO:0045087
  • GO:0050829
  • GO:0050830
  • GO:0050840
  • GO:0062023
  • GO:0098542
  • HMNXSV003043086
  • Hs.124747.0.A1_3p_at
  • ILMN_1763891
  • ILMN_1820437
  • TC19000900.hg
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • SRCRL_HUMAN
  • B5MDQ5
  • C7S7T9
  • C7S7U0
  • K7EP70
sequenceLength 1573
species [Species:48887] Homo sapiens
url https://purl.uniprot.org/uniprot/A1L4H1
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