UniProt:A2VDF0 FUOM

chain
  • chain:1-154
checksum 96F76613566F4A6E
comment
  • FUNCTION Involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes.CATALYTIC ACTIVITY alpha-L-fucose = beta-L-fucosePATHWAY Carbohydrate metabolism; L-fucose metabolism.SUBUNIT Mainly homodimer, but exists also as homotetramer, homooctamer, and homodecamer. The homodimeric form seems catalytically inactive (By similarity).ALTERNATIVE PRODUCTS Belongs to the RbsD / FucU family.
created [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
crossReference
databaseName UniProt
dbId 223895
description
  • recommendedName: Fucose mutarotase ecNumber evidence="2"5.1.3.29
displayName UniProt:A2VDF0 FUOM
geneName
  • FUOM
  • C10orf125
identifier A2VDF0
isSequenceChanged false
keyword
  • Alternative splicing
  • Isomerase
  • Reference proteome
modified [InstanceEdit:12187927] Wright, Adam, 2024-03-12
name
  • FUOM
otherIdentifier
  • 11740730_a_at
  • 11740731_x_at
  • 11741793_a_at
  • 16719882
  • 230259_PM_at
  • 230259_at
  • 282969
  • 3315219
  • 3315220
  • 3315221
  • 3315223
  • 3315224
  • 3315225
  • 3315226
  • 3315227
  • 3315230
  • 7937208
  • 83579_at
  • A_23_P97952
  • A_24_P186379
  • GE87234
  • GO:0003824
  • GO:0005829
  • GO:0005975
  • GO:0005996
  • GO:0006004
  • GO:0016853
  • GO:0016857
  • GO:0036065
  • GO:0036373
  • GO:0042806
  • GO:0048029
  • HMNXSV003020795
  • Hs.155823.0.A1_3p_at
  • Hs.155823.0.A1_3p_x_at
  • ILMN_1704785
  • PH_hs_0031890
  • TC10001789.hg
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • FUCM_HUMAN
  • A1L300
  • Q5VWY2
  • Q5VWY3
  • Q6ZPD2
sequenceLength 154
species [Species:48887] Homo sapiens
url https://purl.uniprot.org/uniprot/A2VDF0
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