created | [InstanceEdit:143359] Matthews, L, 2004-11-09 14:12:28 |
dbId | 143360 |
displayName | The mechanism by which the conformationally altered inhibito... |
modified | [InstanceEdit:9667184] D'Eustachio, Peter, 2019-11-07 |
schemaClass | Summation |
text | The mechanism by which the conformationally altered inhibitory form of Mad2 is released from its association with Mad1 at the kinetochore is not known. Mad1 and Cdc20 have a common 10 residue Mad2 binding motif. Therefore, one possibility is that Mad2 is transferred competitively from Mad1 to Cdc20 (Luo et al., 2002; Sironi et al., 2002). |
(summation) |
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