The mechanism by which the conformationally altered inhibito...

created [InstanceEdit:143359] Matthews, L, 2004-11-09 14:12:28
dbId 143360
displayName The mechanism by which the conformationally altered inhibito...
modified [InstanceEdit:9667184] D'Eustachio, Peter, 2019-11-07
schemaClass Summation
text The mechanism by which the conformationally altered inhibitory form of Mad2 is released from its association with Mad1 at the kinetochore is not known. Mad1 and Cdc20 have a common 10 residue Mad2 binding motif. Therefore, one possibility is that Mad2 is transferred competitively from Mad1 to Cdc20 (Luo et al., 2002; Sironi et al., 2002).
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